319425-66-6,MFCD30146048
Catalog No.:AA01CCGF

319425-66-6 | Furo[2,3-d]pyrimidin-2(3H)-one,3-(2-deoxy-b-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)-

Pack Size
Purity
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Price(USD)
Quantity
  
1mg
100%
1 week  
$190.00   $133.00
- +
5mg
100%
1 week  
$365.00   $256.00
- +
10mg
100%
1 week  
$512.00   $359.00
- +
25mg
100%
1 week  
$730.00   $511.00
- +
50mg
100%
1 week  
$1,015.00   $711.00
- +
100mg
100%
1 week  
$1,383.00   $968.00
- +
500mg
100%
1 week  
$2,709.00   $1,896.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01CCGF
Chemical Name:
Furo[2,3-d]pyrimidin-2(3H)-one,3-(2-deoxy-b-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)-
CAS Number:
319425-66-6
Molecular Formula:
C22H26N2O5
Molecular Weight:
398.4522
MDL Number:
MFCD30146048
SMILES:
CCCCCc1ccc(cc1)c1cc2c(o1)nc(=O)n(c2)[C@H]1C[C@@H]([C@H](O1)CO)O
Properties
Computed Properties
 
Complexity:
708  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.5  

Literature

Title: Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues.

Journal: Journal of medicinal chemistry 20110324

Title: Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.

Journal: Antiviral chemistry & chemotherapy 20101028

Title: 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.

Journal: Bioorganic & medicinal chemistry letters 20091115

Title: FV100 as a new approach for the possible treatment of varicella-zoster virus infection.

Journal: The Journal of antimicrobial chemotherapy 20091001

Title: Synthesis and antiviral activity of the carbocyclic analogue of the highly potent and selective anti-VZV bicyclo furano pyrimidines.

Journal: Journal of medicinal chemistry 20071227

Title: Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.

Journal: The Journal of antimicrobial chemotherapy 20071201

Title: Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.

Journal: Journal of medicinal chemistry 20070809

Title: Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives.

Journal: Journal of medicinal chemistry 20060112

Title: In vitro delivery of novel, highly potent anti-varicella zoster virus nucleoside analogues to their target site in the skin.

Journal: Pharmaceutical research 20040601

Title: Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity.

Journal: Bioorganic & medicinal chemistry letters 20040517

Title: Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.

Journal: Biochemical and biophysical research communications 20040319

Title: Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids 20040101

Title: Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues.

Journal: Medicinal research reviews 20030501

Title: Bicyclic nucleoside inhibitors of varicella-zoster virus: effect of terminal aryl substitution in the side-chain.

Journal: Antiviral chemistry & chemotherapy 20020901

Title: Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.

Journal: Biochimica et biophysica acta 20020718

Title: Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.

Journal: Molecular pharmacology 20020501

Title: Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubility.

Journal: Antiviral chemistry & chemotherapy 20020301

Title: Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents.

Journal: Nucleosides, nucleotides & nucleic acids 20010101

Title: Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain.

Journal: Journal of medicinal chemistry 20001228

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Related Products of 319425-66-6
Tags:319425-66-6 Molecular Formula|319425-66-6 MDL|319425-66-6 SMILES|319425-66-6 Furo[2,3-d]pyrimidin-2(3H)-one,3-(2-deoxy-b-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)-
Catalog No.: AA01CCGF
319425-66-6,MFCD30146048
319425-66-6 | Furo[2,3-d]pyrimidin-2(3H)-one,3-(2-deoxy-b-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)-
Pack Size: 1mg
Purity: 100%
1 week
$190.00 $133.00
Pack Size: 5mg
Purity: 100%
1 week
$365.00 $256.00
Pack Size: 10mg
Purity: 100%
1 week
$512.00 $359.00
Pack Size: 25mg
Purity: 100%
1 week
$730.00 $511.00
Pack Size: 50mg
Purity: 100%
1 week
$1,015.00 $711.00
Pack Size: 100mg
Purity: 100%
1 week
$1,383.00 $968.00
Pack Size: 500mg
Purity: 100%
1 week
$2,709.00 $1,896.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01CCGF
Chemical Name: Furo[2,3-d]pyrimidin-2(3H)-one,3-(2-deoxy-b-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)-
CAS Number: 319425-66-6
Molecular Formula: C22H26N2O5
Molecular Weight: 398.4522
MDL Number: MFCD30146048
SMILES: CCCCCc1ccc(cc1)c1cc2c(o1)nc(=O)n(c2)[C@H]1C[C@@H]([C@H](O1)CO)O
Properties
Complexity: 708  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 3  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 29  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.5  
Literature fold

Title: Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues.

Journal: Journal of medicinal chemistry20110324

Title: Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.

Journal: Antiviral chemistry & chemotherapy20101028

Title: 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.

Journal: Bioorganic & medicinal chemistry letters20091115

Title: FV100 as a new approach for the possible treatment of varicella-zoster virus infection.

Journal: The Journal of antimicrobial chemotherapy20091001

Title: Synthesis and antiviral activity of the carbocyclic analogue of the highly potent and selective anti-VZV bicyclo furano pyrimidines.

Journal: Journal of medicinal chemistry20071227

Title: Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.

Journal: The Journal of antimicrobial chemotherapy20071201

Title: Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.

Journal: Journal of medicinal chemistry20070809

Title: Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives.

Journal: Journal of medicinal chemistry20060112

Title: In vitro delivery of novel, highly potent anti-varicella zoster virus nucleoside analogues to their target site in the skin.

Journal: Pharmaceutical research20040601

Title: Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity.

Journal: Bioorganic & medicinal chemistry letters20040517

Title: Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.

Journal: Biochemical and biophysical research communications20040319

Title: Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids20040101

Title: Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues.

Journal: Medicinal research reviews20030501

Title: Bicyclic nucleoside inhibitors of varicella-zoster virus: effect of terminal aryl substitution in the side-chain.

Journal: Antiviral chemistry & chemotherapy20020901

Title: Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.

Journal: Biochimica et biophysica acta20020718

Title: Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.

Journal: Molecular pharmacology20020501

Title: Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubility.

Journal: Antiviral chemistry & chemotherapy20020301

Title: Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents.

Journal: Nucleosides, nucleotides & nucleic acids20010101

Title: Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain.

Journal: Journal of medicinal chemistry20001228

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