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69-25-0,MFCD00076373
Catalog No.:AA01DQ4X

69-25-0 | Eledoisin

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1mg
≥98%
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$123.00   $86.00
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5mg
≥98%
in stock  
$480.00   $336.00
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10mg
≥98%
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$840.00   $588.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DQ4X
Chemical Name:
Eledoisin
CAS Number:
69-25-0
Molecular Formula:
C54H85N13O15S
Molecular Weight:
1188.3958
MDL Number:
MFCD00076373
SMILES:
NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N)CCSC)CC(C)C)C(CC)C)Cc1ccccc1)C)CC(=O)O)NC(=O)C(NC(=O)C1CCCN1C(=O)C1CCC(=O)N1)CO
Properties
Computed Properties
 
Complexity:
2270  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
83  
Hydrogen Bond Acceptor Count:
17  
Hydrogen Bond Donor Count:
14  
Rotatable Bond Count:
36  
XLogP3:
-3.6  

Literature

Title: Chromatographic behaviour of peptides on a mixed-mode stationary phase with an embedded charged group by capillary electrochromatography and high-performance liquid chromatography.

Journal: Journal of chromatography. A 20061215

Title: N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II.

Journal: Bioorganic & medicinal chemistry letters 20061115

Title: N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20061115

Title: Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin.

Journal: Peptides 20041101

Title: Solution structure of the tachykinin peptide eledoisin.

Journal: Biophysical journal 20030101

Title: The roles of the N-terminal portions of various tachykinins in promoting salivation.

Journal: Oral diseases 20010701

Title: The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity.

Journal: The Journal of biological chemistry 19960823

Title: Cyclic hexapeptide NK-2 antagonists.

Journal: International journal of peptide and protein research 19940801

Title: Molecular characterisation, expression and localisation of human neurokinin-3 receptor.

Journal: FEBS letters 19920324

Title: [Synthesis of cyclic and cyclically branched tachykinin partial sequences. 1. Synthesis of the homodet-cyclic eledoisin(6-11)-hexapeptide].

Journal: Die Pharmazie 19850701

Title: Synthesis and hypotensive activity of some analogs of the C-terminal hexapeptideamide of eledoisin.

Journal: Arzneimittel-Forschung 19800101

Title: Lippe C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5.

Title: Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322.

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