Title: LYG-202 augments tumor necrosis factor-α-induced apoptosis via attenuating casein kinase 2-dependent nuclear factor-κB pathway in HepG2 cells.
Journal: Molecular pharmacology 20121101
Title: LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601
Title: Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.
Journal: Cancer letters 20101001
Title: LYG-202, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo.
Journal: Journal of pharmacological sciences 20100101
Title: LYG-202, a new flavonoid with a piperazine substitution, shows antitumor effects in vivo and in vitro.
Journal: Biochemical and biophysical research communications 20090807