Home Other Building Blocks 1175077-25-4
1175077-25-4,MFCD26793880
Catalog No.:AA01DZQF

1175077-25-4 | LYG-202

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$166.00   $116.00
- +
10mg
≥98%
in stock  
$306.00   $214.00
- +
25mg
≥98%
in stock  
$706.00   $494.00
- +
50mg
in stock  
$1,225.00   $858.00
- +
100mg
in stock  
$2,074.00   $1,452.00
- +
500mg
in stock  
$6,554.00   $4,588.00
- +
1000mg
in stock  
$10,449.00   $7,314.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DZQF
Chemical Name:
LYG-202
CAS Number:
1175077-25-4
Molecular Formula:
C25H30N2O5
Molecular Weight:
438.5161
MDL Number:
MFCD26793880
SMILES:
COc1c(OCCCCN2CCN(CC2)C)cc(c2c1oc(cc2=O)c1ccccc1)O
Properties
Computed Properties
 
Complexity:
642  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  
XLogP3:
3.9  

Literature

Title: LYG-202 augments tumor necrosis factor-α-induced apoptosis via attenuating casein kinase 2-dependent nuclear factor-κB pathway in HepG2 cells.

Journal: Molecular pharmacology 20121101

Title: LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601

Title: Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.

Journal: Cancer letters 20101001

Title: LYG-202, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo.

Journal: Journal of pharmacological sciences 20100101

Title: LYG-202, a new flavonoid with a piperazine substitution, shows antitumor effects in vivo and in vitro.

Journal: Biochemical and biophysical research communications 20090807

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Tags:1175077-25-4 Molecular Formula|1175077-25-4 MDL|1175077-25-4 SMILES|1175077-25-4 LYG-202