Home Other Building Blocks 1245626-05-4
1245626-05-4,MFCD19053178
Catalog No.:AA01E0DK

1245626-05-4 | AM6545

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
98% by HPLC
in stock  
$224.00   $157.00
- +
10mg
98% by HPLC
in stock  
$335.00   $234.00
- +
25mg
98% by HPLC
in stock  
$637.00   $446.00
- +
50mg
98% by HPLC
in stock  
$1,040.00   $728.00
- +
100mg
98% by HPLC
in stock  
$1,752.00   $1,227.00
- +
500mg
98% by HPLC
in stock  
$5,515.00   $3,861.00
- +
1000mg
98% by HPLC
in stock  
$8,787.00   $6,151.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01E0DK
Chemical Name:
AM6545
CAS Number:
1245626-05-4
Molecular Formula:
C26H23Cl2N5O3S
Molecular Weight:
556.4635
MDL Number:
MFCD19053178
SMILES:
N#CCCC#Cc1ccc(cc1)c1c(C)c(nn1c1ccc(cc1Cl)Cl)C(=O)NN1CCS(=O)(=O)CC1
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
4.5  

Literature

Title: Crystal Structure of the Human Cannabinoid Receptor CB(1).

Journal: Cell 20161020

Title: A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20150106

Title: Central mediation and differential blockade by cannabinergics of the discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats.

Journal: Psychopharmacology 20110801

Title: The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior.

Journal: Pharmacology, biochemistry, and behavior 20101101

Title: Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats.

Journal: British journal of pharmacology 20100901

Title: Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.

Journal: The Journal of clinical investigation 20100802

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SDS
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