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224624-80-0,MFCD09970762
Catalog No.:AA01E3R5

224624-80-0 | Miridesap

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$6.00   $4.00
- +
5mg
97%
in stock  
$9.00   $7.00
- +
10mg
97%
in stock  
$13.00   $9.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01E3R5
Chemical Name:
Miridesap
CAS Number:
224624-80-0
Molecular Formula:
C16H24N2O6
Molecular Weight:
340.3716
MDL Number:
MFCD09970762
SMILES:
OC(=O)[C@H]1CCCN1C(=O)CCCCC(=O)N1CCC[C@@H]1C(=O)O
Properties
Computed Properties
 
Complexity:
475  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  

Downstream Synthesis Route

[1]Patent:US2003/134891,2003,A1

224624-80-0    2675-89-0   
(R)-1-{6-(R)-2-(dimethylcarbamoyl-methoxycarbonyl)-pyrrolidin-1-yl-6-oxo-hexanoyl}-pyrrolidine-2-carboxylicaciddimethylcarbamoyl-methylester 

[1]Patent:US2003/134891,2003,A1

[1]Patent:US2003/134891,2003,A1

[1]Patent:US2003/134891,2003,A1

224624-80-0    158890-31-4   
(R)-1-{6-(R)-2-(tert-butylmethylcarbamoyl-methoxycarbonyl)-pyrrolidin-1-yl-6-oxo-hexanoyl}-pyrrolidine-2-carboxylicacidtert-butylmethylcarbamoyl-methylester 

[1]Patent:US2003/134891,2003,A1

Literature

Title: [New trends in the treatment of amyloidosis].

Journal: Medicina clinica 20120526

Title: Immunoradiometric assay for human serum amyloid P component.

Journal: Journal of immunological methods 20110831

Title: Light chain (AL) amyloidosis: update on diagnosis and management.

Journal: Journal of hematology & oncology 20110101

Title: Antibodies to human serum amyloid P component eliminate visceral amyloid deposits.

Journal: Nature 20101104

Title: Drug targets for amyloidosis.

Journal: Biochemical Society transactions 20100401

Title: Sustained pharmacological depletion of serum amyloid P component in patients with systemic amyloidosis.

Journal: British journal of haematology 20100301

Title: Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090505

Title: Drug Insight: emerging therapies for amyloidosis.

Journal: Nature clinical practice. Nephrology 20060501

Title: Selective optimization of side activities: another way for drug discovery.

Journal: Journal of medicinal chemistry 20040311

Title: Amyloidosis: a clinico-pathophysiological synopsis.

Journal: Seminars in cell & developmental biology 20040201

Title: [Novel therapeutic approach to amyloidosis: no implications as yet for patients with Alzheimer's disease].

Journal: Nederlands tijdschrift voor geneeskunde 20020914

Title: Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis.

Journal: Nature 20020516

Title: Influenza virus infection is not affected by serum amyloid P component.

Journal: Molecular medicine (Cambridge, Mass.) 20020101

Title: Kolstoe SE, et al. Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7619-23.

Title: Sahota T,et al. Target Mediated Drug Disposition Model of CPHPC in Patients with Systemic Amyloidosis. CPT Pharmacometrics Syst Pharmacol. 2015 Feb;4(2):e15.

Quotation Request
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SDS
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Tags:224624-80-0 Molecular Formula|224624-80-0 MDL|224624-80-0 SMILES|224624-80-0 Miridesap
Catalog No.: AA01E3R5
224624-80-0,MFCD09970762
224624-80-0 | Miridesap
Pack Size： 1mg
Purity： 97%
in stock
$6.00 $4.00
Pack Size： 5mg
Purity： 97%
in stock
$9.00 $7.00
Pack Size： 10mg
Purity： 97%
in stock
$13.00 $9.00
Quantity
- +
Add to Card
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Technical Information
Catalog Number: AA01E3R5
Chemical Name: Miridesap
CAS Number: 224624-80-0
Molecular Formula: C16H24N2O6
Molecular Weight: 340.3716
MDL Number: MFCD09970762
SMILES: OC(=O)[C@H]1CCCN1C(=O)CCCCC(=O)N1CCC[C@@H]1C(=O)O
Properties
Complexity: 475  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 24  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 7  
Downstream Synthesis Route
186581-53-3    224624-80-0    548487-27-0 

[1]Patent:US2003/134891,2003,A1

224624-80-0    2675-89-0   
(R)-1-{6-(R)-2-(dimethylcarbamoyl-methoxycarbonyl)-pyrrolidin-1-yl-6-oxo-hexanoyl}-pyrrolidine-2-carboxylicaciddimethylcarbamoyl-methylester 

[1]Patent:US2003/134891,2003,A1

224624-80-0    79-07-2    548487-18-9 

[1]Patent:US2003/134891,2003,A1

224624-80-0    13269-97-1    548487-19-0 

[1]Patent:US2003/134891,2003,A1

224624-80-0    158890-31-4   
(R)-1-{6-(R)-2-(tert-butylmethylcarbamoyl-methoxycarbonyl)-pyrrolidin-1-yl-6-oxo-hexanoyl}-pyrrolidine-2-carboxylicacidtert-butylmethylcarbamoyl-methylester 

[1]Patent:US2003/134891,2003,A1

Literature fold

Title: [New trends in the treatment of amyloidosis].

Journal: Medicina clinica20120526

Title: Immunoradiometric assay for human serum amyloid P component.

Journal: Journal of immunological methods20110831

Title: Light chain (AL) amyloidosis: update on diagnosis and management.

Journal: Journal of hematology & oncology20110101

Title: Antibodies to human serum amyloid P component eliminate visceral amyloid deposits.

Journal: Nature20101104

Title: Drug targets for amyloidosis.

Journal: Biochemical Society transactions20100401

Title: Sustained pharmacological depletion of serum amyloid P component in patients with systemic amyloidosis.

Journal: British journal of haematology20100301

Title: Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.

Journal: Proceedings of the National Academy of Sciences of the United States of America20090505

Title: Drug Insight: emerging therapies for amyloidosis.

Journal: Nature clinical practice. Nephrology20060501

Title: Selective optimization of side activities: another way for drug discovery.

Journal: Journal of medicinal chemistry20040311

Title: Amyloidosis: a clinico-pathophysiological synopsis.

Journal: Seminars in cell & developmental biology20040201

Title: [Novel therapeutic approach to amyloidosis: no implications as yet for patients with Alzheimer's disease].

Journal: Nederlands tijdschrift voor geneeskunde20020914

Title: Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis.

Journal: Nature20020516

Title: Influenza virus infection is not affected by serum amyloid P component.

Journal: Molecular medicine (Cambridge, Mass.)20020101

Title: Kolstoe SE, et al. Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7619-23.

Title: Sahota T,et al. Target Mediated Drug Disposition Model of CPHPC in Patients with Systemic Amyloidosis. CPT Pharmacometrics Syst Pharmacol. 2015 Feb;4(2):e15.

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