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55486-00-5,MFCD00083306
Catalog No.:AA01E4NL

55486-00-5 | 2-Decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

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5mg
≥98%
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$50.00   $35.00
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10mg
≥98%
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$76.00   $53.00
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25mg
≥98%
in stock  
$176.00   $123.00
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50mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01E4NL
Chemical Name:
2-Decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
CAS Number:
55486-00-5
Molecular Formula:
C19H30O4
Molecular Weight:
322.4391
MDL Number:
MFCD00083306
SMILES:
CCCCCCCCCCC1=C(C)C(=O)C(=C(C1=O)OC)OC
Properties
Properties
 
BP:
452.9°C at 760 mmHg  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
486  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
11  
XLogP3:
6  

Literature

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Expression of Saccharomyces cerevisiae Sdh3p and Sdh4p paralogs results in catalytically active succinate dehydrogenase isoenzymes.

Journal: The Journal of biological chemistry 20120629

Title: Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function.

Journal: Eukaryotic cell 20110801

Title: New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): the significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals.

Journal: Biochimica et biophysica acta 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Decylubiquinone increases mitochondrial function in synaptosomes.

Journal: The Journal of biological chemistry 20100319

Title: Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death.

Journal: PloS one 20100101

Title: Modeling of human pathogenic mutations in Escherichia coli complex I reveals a sensitive region in the fourth inside loop of NuoH.

Journal: Mitochondrion 20091101

Title: Mitochondrial calcium transport and mitochondrial dysfunction after global brain ischemia in rat hippocampus.

Journal: Neurochemical research 20090801

Title: Decylubiquinol impedes mitochondrial respiratory chain complex I activity.

Journal: Molecular and cellular biochemistry 20080701

Title: Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.

Journal: Nature chemical biology 20080701

Title: Activity of 1,4-benzoquinones against formosan subterranean termites (Coptotermes formosanus).

Journal: Journal of agricultural and food chemistry 20080611

Title: Is cytochrome b glutamic acid 272 a quinol binding residue in the bc1 complex of Saccharomyces cerevisiae?

Journal: Biochemistry 20080226

Title: Functional role of coenzyme Q in the energy coupling of NADH-CoQ oxidoreductase (Complex I): stabilization of the semiquinone state with the application of inside-positive membrane potential to proteoliposomes.

Journal: BioFactors (Oxford, England) 20080101

Title: Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues.

Journal: BioFactors (Oxford, England) 20080101

Title: Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase.

Journal: Journal of medicinal chemistry 20070125

Title: Effects of decylubiquinone (coenzyme Q10 analog) supplementation on SHRSP.

Journal: BioFactors (Oxford, England) 20070101

Title: Steady-state kinetics and inhibitory action of antitubercular phenothiazines on mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2).

Journal: The Journal of biological chemistry 20060428

Title: Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.

Journal: Anti-cancer drugs 20051001

Title: Interaction of FXYD10 (PLMS) with Na,K-ATPase from shark rectal glands. Close proximity of Cys74 of FXYD10 to Cys254 in the a domain of the alpha-subunit revealed by intermolecular thiol cross-linking.

Journal: The Journal of biological chemistry 20050729

Title: Quinone analogues regulate mitochondrial substrate competitive oxidation.

Journal: Biochemical and biophysical research communications 20040416

Title: Anti-cooperative oxidation of ubiquinol by the yeast cytochrome bc1 complex.

Journal: The Journal of biological chemistry 20040409

Title: Human disease-related mutations in cytochrome b studied in yeast.

Journal: The Journal of biological chemistry 20040326

Title: Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers.

Journal: Biochemistry 20040316

Title: The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: role of mitcohondrial [correction mitochondrial] complex III.

Journal: The Journal of biological chemistry 20031205

Title: Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001

Title: Effect of pH on the steady state kinetics of bovine heart NADH: coenzyme Q oxidoreductase.

Journal: Journal of bioenergetics and biomembranes 20031001

Title: Mutagenesis of subunit N of the Escherichia coli complex I. Identification of the initiation codon and the sensitivity of mutants to decylubiquinone.

Journal: Biochemistry 20030506

Title: Diclofenac induces apoptosis in hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030101

Title: Activation of caspases and cleavage of Bid are required for tyrosine and phenylalanine deficiency-induced apoptosis of human A375 melanoma cells.

Journal: Archives of biochemistry and biophysics 20020701

Title: The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c.

Journal: The Journal of biological chemistry 20020510

Title: Interaction of purified NDH-1 from Escherichia coli with ubiquinone analogues.

Journal: Biochimica et biophysica acta 20020215

Title: Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling.

Journal: Biochimica et biophysica acta 20010702

Title: Functional characterization of novel mutations in the human cytochrome b gene.

Journal: European journal of human genetics : EJHG 20010701

Title: Electrogenic proton transfer in Rhodobacter sphaeroides reaction centers: effect of coenzyme Q(10) substitution by decylubiquinone in the Q(B) binding site.

Journal: FEBS letters 20010615

Title: Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives.

Journal: Biochemical pharmacology 19981101

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Tags:55486-00-5 Molecular Formula|55486-00-5 MDL|55486-00-5 SMILES|55486-00-5 2-Decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione