169332-61-0,MFCD00671411
Catalog No.:AA01E6SR

169332-61-0 | Ac-Asp-Glu-Val-Asp-AMC ammonium salt

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Purity
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1mg
≥95%
in stock  
$88.00   $61.00
- +
5mg
≥95%
in stock  
$232.00   $162.00
- +
10mg
≥95%
in stock  
$393.00   $275.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01E6SR
Chemical Name:
Ac-Asp-Glu-Val-Asp-AMC ammonium salt
CAS Number:
169332-61-0
Molecular Formula:
C30H37N5O13
Molecular Weight:
675.6405
MDL Number:
MFCD00671411
SMILES:
OC(=O)C[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(=O)O)CCC(=O)O
Properties
Computed Properties
 
Complexity:
1330  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
48  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
17  
XLogP3:
-1.3  

Literature

Title: Isolation and prevention of calcium oxalate-induced apoptotic death and oxidative stress in MDCK cells by diosgenin.

Journal: Chemico-biological interactions 20141205

Title: A secreted caspase-3-substrate-cleaving activity at low pH belongs to cathepsin B: a study on primary brain cell cultures.

Journal: Biochemistry. Biokhimiia 20090301

Title: Brain cathepsin B cleaves a caspase substrate.

Journal: Biochemistry. Biokhimiia 20080301

Title: Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway.

Journal: Cancer letters 20070108

Title: PepBank--a database of peptides based on sequence text mining and public peptide data sources.

Journal: BMC bioinformatics 20070101

Title: Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay.

Journal: Analytical biochemistry 20060301

Title: Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

Journal: Journal of neurochemistry 20050301

Title: Region of caspase-3 activation and programmed cell death in the early development of the mouse forebrain.

Journal: Brain research. Developmental brain research 20031112

Title: Biochemical analysis of the molecular mechanism of action of natural integrin inhibitors.

Journal: Veterinary research communications 20030901

Title: Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis.

Journal: Acta neuropathologica 20030501

Title: Caspase-mediated apoptosis in sponges: cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa.

Journal: Biochimica et biophysica acta 20030217

Title: Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin.

Journal: Cell biology international 20030101

Title: Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion.

Journal: FEBS letters 20020911

Title: Huperzine A attenuates amyloid beta-peptide fragment 25-35-induced apoptosis in rat cortical neurons via inhibiting reactive oxygen species formation and caspase-3 activation.

Journal: Journal of neuroscience research 20020101

Title: Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo.

Journal: The Biochemical journal 20011115

Title: Caspase activity is involved in, but is dispensable for, early motoneuron death in the chick embryo cervical spinal cord.

Journal: Molecular and cellular neurosciences 20010801

Title: Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis.

Journal: Journal of neuroscience research 20010701

Title: Detection of caspase-activation in intact lymphoid cells using standard caspase substrates and inhibitors.

Journal: Journal of immunological methods 20000731

Title: Caspase-dependent activation of calpain during drug-induced apoptosis.

Journal: The Journal of biological chemistry 19990319

Title: Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells.

Journal: Journal of neurochemistry 19990101

Title: Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19981015

Title: Caspase activation and specific cleavage of substrates after coxsackievirus B3-induced cytopathic effect in HeLa cells.

Journal: Journal of virology 19980901

Title: Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells.

Journal: Journal of neurochemistry 19980601

Title: Chae HJ, et al. Je-chun-jun induced apoptosis of human cervical carcinoma HeLa cells. Acta Pharmacol Sin. 2004 Oct;25(10):1372-9.

Title: Ahmed R Alsuwaidi, et al. Bioenergetics of murine lungs infected with respiratory syncytial virus. Virol J. 2013; 10: 22.

Title: Ahmed R Alsuwaidi, et al. Lung tissue bioenergetics and caspase activity in rodents. BMC Res Notes. 2013; 6: 12.

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SDS
Tags:169332-61-0 Molecular Formula|169332-61-0 MDL|169332-61-0 SMILES|169332-61-0 Ac-Asp-Glu-Val-Asp-AMC ammonium salt
Catalog No.: AA01E6SR
169332-61-0,MFCD00671411
169332-61-0 | Ac-Asp-Glu-Val-Asp-AMC ammonium salt
Pack Size: 1mg
Purity: ≥95%
in stock
$88.00 $61.00
Pack Size: 5mg
Purity: ≥95%
in stock
$232.00 $162.00
Pack Size: 10mg
Purity: ≥95%
in stock
$393.00 $275.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01E6SR
Chemical Name: Ac-Asp-Glu-Val-Asp-AMC ammonium salt
CAS Number: 169332-61-0
Molecular Formula: C30H37N5O13
Molecular Weight: 675.6405
MDL Number: MFCD00671411
SMILES: OC(=O)C[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(=O)O)CCC(=O)O
Properties
Complexity: 1330  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 4  
Heavy Atom Count: 48  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 8  
Rotatable Bond Count: 17  
XLogP3: -1.3  
Literature fold

Title: Isolation and prevention of calcium oxalate-induced apoptotic death and oxidative stress in MDCK cells by diosgenin.

Journal: Chemico-biological interactions20141205

Title: A secreted caspase-3-substrate-cleaving activity at low pH belongs to cathepsin B: a study on primary brain cell cultures.

Journal: Biochemistry. Biokhimiia20090301

Title: Brain cathepsin B cleaves a caspase substrate.

Journal: Biochemistry. Biokhimiia20080301

Title: Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway.

Journal: Cancer letters20070108

Title: PepBank--a database of peptides based on sequence text mining and public peptide data sources.

Journal: BMC bioinformatics20070101

Title: Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay.

Journal: Analytical biochemistry20060301

Title: Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

Journal: Journal of neurochemistry20050301

Title: Region of caspase-3 activation and programmed cell death in the early development of the mouse forebrain.

Journal: Brain research. Developmental brain research20031112

Title: Biochemical analysis of the molecular mechanism of action of natural integrin inhibitors.

Journal: Veterinary research communications20030901

Title: Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis.

Journal: Acta neuropathologica20030501

Title: Caspase-mediated apoptosis in sponges: cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa.

Journal: Biochimica et biophysica acta20030217

Title: Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin.

Journal: Cell biology international20030101

Title: Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion.

Journal: FEBS letters20020911

Title: Huperzine A attenuates amyloid beta-peptide fragment 25-35-induced apoptosis in rat cortical neurons via inhibiting reactive oxygen species formation and caspase-3 activation.

Journal: Journal of neuroscience research20020101

Title: Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo.

Journal: The Biochemical journal20011115

Title: Caspase activity is involved in, but is dispensable for, early motoneuron death in the chick embryo cervical spinal cord.

Journal: Molecular and cellular neurosciences20010801

Title: Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis.

Journal: Journal of neuroscience research20010701

Title: Detection of caspase-activation in intact lymphoid cells using standard caspase substrates and inhibitors.

Journal: Journal of immunological methods20000731

Title: Caspase-dependent activation of calpain during drug-induced apoptosis.

Journal: The Journal of biological chemistry19990319

Title: Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells.

Journal: Journal of neurochemistry19990101

Title: Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience19981015

Title: Caspase activation and specific cleavage of substrates after coxsackievirus B3-induced cytopathic effect in HeLa cells.

Journal: Journal of virology19980901

Title: Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells.

Journal: Journal of neurochemistry19980601

Title: Chae HJ, et al. Je-chun-jun induced apoptosis of human cervical carcinoma HeLa cells. Acta Pharmacol Sin. 2004 Oct;25(10):1372-9.

Title: Ahmed R Alsuwaidi, et al. Bioenergetics of murine lungs infected with respiratory syncytial virus. Virol J. 2013; 10: 22.

Title: Ahmed R Alsuwaidi, et al. Lung tissue bioenergetics and caspase activity in rodents. BMC Res Notes. 2013; 6: 12.

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