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566203-88-1,MFCD31382158
Catalog No.:AA01EA8F

566203-88-1 | AZD 2098 - Bio-X

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$11.00   $8.00
- +
5mg
98+%
in stock  
$25.00   $18.00
- +
10mg
98+%
in stock  
$37.00   $26.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EA8F
Chemical Name:
AZD 2098 - Bio-X
CAS Number:
566203-88-1
Molecular Formula:
C11H9Cl2N3O3S
Molecular Weight:
334.1785
MDL Number:
MFCD31382158
SMILES:
COc1nccnc1NS(=O)(=O)c1cccc(c1Cl)Cl
Properties
Computed Properties
 
Complexity:
418  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.6  

Downstream Synthesis Route

[1]Kindon,Nicholas;Andrews,Glen;Baxter,Andrew;Cheshire,David;Hemsley,Paul;Johnson,Timothy;Liu,Yu-Zhen;McGinnity,Dermot;McHale,Mark;Mete,Antonio;Reuberson,James;Roberts,Bryan;Steele,John;Teobald,Barry;Unitt,John;Vaughan,Deborah;Walters,Iain;Stocks,MichaelJ.[ACSMedicinalChemistryLetters,2017,vol.8,#9,p.981-986]

[2]CurrentPatentAssignee:ASTRAZENECAPLC-WO2007/69978,2007,A1Locationinpatent:Page/Pagecolumn28

[1]Kindon,Nicholas;Andrews,Glen;Baxter,Andrew;Cheshire,David;Hemsley,Paul;Johnson,Timothy;Liu,Yu-Zhen;McGinnity,Dermot;McHale,Mark;Mete,Antonio;Reuberson,James;Roberts,Bryan;Steele,John;Teobald,Barry;Unitt,John;Vaughan,Deborah;Walters,Iain;Stocks,MichaelJ.[ACSMedicinalChemistryLetters,2017,vol.8,#9,p.981-986]

[1]Kindon,Nicholas;Andrews,Glen;Baxter,Andrew;Cheshire,David;Hemsley,Paul;Johnson,Timothy;Liu,Yu-Zhen;McGinnity,Dermot;McHale,Mark;Mete,Antonio;Reuberson,James;Roberts,Bryan;Steele,John;Teobald,Barry;Unitt,John;Vaughan,Deborah;Walters,Iain;Stocks,MichaelJ.[ACSMedicinalChemistryLetters,2017,vol.8,#9,p.981-986]

5900-13-0   
2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide 

[1]ACSMedicinalChemistryLetters,2017,vol.8,p.981-986

4774-10-1    82417-45-6   
2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide 

[1]ACSMedicinalChemistryLetters,2017,vol.8,p.981-986

Literature

Title: Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.

Journal: ACS medicinal chemistry letters 20170914

Title: Kindon N, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986.

Title: Asher Mullard. Cancer charity sees success re-prioritizing industry's shelved compounds. Nat Rev Drug Discov. 2014 May;13(5):319-21.

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