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154566-12-8,MFCD28127018
Catalog No.:AA01ENKI

154566-12-8 | (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanaceticacid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$63.00   $44.00
- +
5mg
≥95%
in stock  
$159.00   $111.00
- +
10mg
≥95%
in stock  
$283.00   $198.00
- +
50mg
≥98%(HPLC)
in stock  
$1,320.00   $924.00
- +
100mg
≥98%(HPLC)
in stock  
$2,249.00   $1,574.00
- +
500mg
98% by HPLC
in stock  
$8,111.00   $5,678.00
- +
1000mg
98% by HPLC
in stock  
$12,941.00   $9,059.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01ENKI
Chemical Name:
(3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanaceticacid
CAS Number:
154566-12-8
Molecular Formula:
C18H22Cl2O5
Molecular Weight:
389.2703
MDL Number:
MFCD28127018
SMILES:
OC(=O)C[C@@]1(O)C[C@H](OC1=O)CCCCCCc1ccc(cc1Cl)Cl
Properties
Computed Properties
 
Complexity:
472  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  
XLogP3:
5.1  

Literature

Title: Highly efficient and concise synthesis of both antipodes of SB204900, clausenamide, neoclausenamide, homoclausenamide and zeta-clausenamide. Implication of biosynthetic pathways of Clausena alkaloids.

Journal: Organic & biomolecular chemistry 20090621

Title: The biology and chemistry of hyperlipidemia.

Journal: Bioorganic & medicinal chemistry 20070715

Title: ATP citrate lyase inhibition can suppress tumor cell growth.

Journal: Cancer cell 20051001

Title: The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus.

Journal: Metabolism: clinical and experimental 20040101

Title: Shares BH, et al. Active mitochondria support osteogenic differentiation by stimulating β-catenin acetylation. J Biol Chem. 2018 Oct 12;293(41):16019-16027.

Title: Pearce NJ, et al. The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076. Biochem J. 1998 Aug 15;334 ( Pt 1):113-9.

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SDS
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Tags:154566-12-8 Molecular Formula|154566-12-8 MDL|154566-12-8 SMILES|154566-12-8 (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanaceticacid