Home Other Building Blocks 2093386-22-0
2093386-22-0,MFCD31692340
Catalog No.:AA01ENUB

2093386-22-0 | PROTAC BET Degrader-1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$924.00   $647.00
- +
10mg
98%
1 week  
$1,400.00   $980.00
- +
25mg
98%
1 week  
$2,987.00   $2,091.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01ENUB
Chemical Name:
PROTAC BET Degrader-1
CAS Number:
2093386-22-0
Molecular Formula:
C44H45N11O9
Molecular Weight:
871.8964
MDL Number:
MFCD31692340
SMILES:
CCn1nc(cc1Nc1nc(nc2c1c1cc(OC)c(cc1[nH]2)c1c(C)noc1C)C(=O)NCCCCNC(=O)COc1cccc2c1C(=O)N(C2=O)C1CCC(=O)NC1=O)C1CC1
Properties
Computed Properties
 
Complexity:
1770  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
64  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
16  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.8  

Literature

Title: Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 2093386-22-0
Tags:2093386-22-0 Molecular Formula|2093386-22-0 MDL|2093386-22-0 SMILES|2093386-22-0 PROTAC BET Degrader-1