+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
204067-52-7,MFCD22572763
Catalog No.:AA01EO0G

204067-52-7 | FR194738

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$503.00   $352.00
- +
5mg
98%
1 week  
$1,003.00   $702.00
- +
10mg
98%
1 week  
$1,717.00   $1,202.00
- +
25mg
98%
1 week  
$3,146.00   $2,202.00
- +
50mg
98%
1 week  
$4,654.00   $3,258.00
- +
100mg
98%
1 week  
$6,876.00   $4,813.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EO0G
Chemical Name:
FR194738
CAS Number:
204067-52-7
Molecular Formula:
C27H38ClNO2S
Molecular Weight:
476.1141
MDL Number:
MFCD22572763
SMILES:
CCN(Cc1cccc(c1)OCC(OCc1cscc1)(C)C)C/C=C/C#CC(C)(C)C.Cl
Properties
Computed Properties
 
Complexity:
610  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
12  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters.

Journal: Biological & pharmaceutical bulletin 20021201

Title: Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells.

Journal: European journal of pharmacology 20011109

Title: Sawada M, et al. Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells. Eur J Pharmacol. 2001 Nov 9;431(1):11-6.

Title: Sawada M, et al. Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738. Bioorg Med Chem Lett. 2004 Feb 9;14(3):633-7.

Title: Sawada M, et al. Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters. Biol Pharm Bull. 2002 Dec;25(12):1577-82.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 204067-52-7
204067-45-8

204067-45-8

 204067-52-7

204067-52-7

 204067-45-8

204067-45-8

 204067-45-8

204067-45-8

 204067-45-8

204067-45-8
Building Blocks
More >
Tags:204067-52-7 Molecular Formula|204067-52-7 MDL|204067-52-7 SMILES|204067-52-7 FR194738
Catalog No.: AA01EO0G
204067-52-7,MFCD22572763
204067-52-7 | FR194738
Pack Size： 1mg
Purity： 98%
1 week
$503.00 $352.00
Pack Size： 5mg
Purity： 98%
1 week
$1,003.00 $702.00
Pack Size： 10mg
Purity： 98%
1 week
$1,717.00 $1,202.00
Pack Size： 25mg
Purity： 98%
1 week
$3,146.00 $2,202.00
Pack Size： 50mg
Purity： 98%
1 week
$4,654.00 $3,258.00
Pack Size： 100mg
Purity： 98%
1 week
$6,876.00 $4,813.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EO0G
Chemical Name: FR194738
CAS Number: 204067-52-7
Molecular Formula: C27H38ClNO2S
Molecular Weight: 476.1141
MDL Number: MFCD22572763
SMILES: CCN(Cc1cccc(c1)OCC(OCc1cscc1)(C)C)C/C=C/C#CC(C)(C)C.Cl
Properties
Complexity: 610  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 32  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 12  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738.

Journal: Bioorganic & medicinal chemistry letters20040209

Title: Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters.

Journal: Biological & pharmaceutical bulletin20021201

Title: Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells.

Journal: European journal of pharmacology20011109

Title: Sawada M, et al. Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells. Eur J Pharmacol. 2001 Nov 9;431(1):11-6.

Title: Sawada M, et al. Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738. Bioorg Med Chem Lett. 2004 Feb 9;14(3):633-7.

Title: Sawada M, et al. Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters. Biol Pharm Bull. 2002 Dec;25(12):1577-82.

Related Products of of 204067-52-7
204067-45-8
204067-45-8
204067-52-7
204067-52-7
204067-45-8
204067-45-8
204067-45-8
204067-45-8
204067-45-8
204067-45-8
Building Blocks More >
2036044-77-4
2036044-77-4
Porcupine-IN-1
AA01EO3O | MFCD31630804
333745-53-2
333745-53-2
LX2343
AA01EO7B | MFCD02578482
1808094-07-6
1808094-07-6
PF-06471553
AA01EOEL | MFCD31657365
1088543-62-7
1088543-62-7
AZP-531
AA01EOK0 | MFCD31544369
1597402-27-1
1597402-27-1
JPH203 Dihydrochloride
AA01EOO3 | MFCD31619323
133438-58-1
133438-58-1
(4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-methanone
AA01EOXI
911378-38-6
911378-38-6
N-[1-[(4-iodophenyl)methyl]-4-piperidinyl]-N-methyl-3-(1-methylethoxy)-2-pyridinamine(2Z)-2-butenedioate
AA01EP7R | MFCD01321055
1636134-73-0
1636134-73-0
10-[(1-oxohexadecyl)oxy]-octadecanoicacid
AA01EPG1
73167-03-0
73167-03-0
Sodium (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
AA01EPLJ | MFCD00079184
2070009-41-3
2070009-41-3
(3R,5S,E)-7-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)-6-(propan-2-yl-1,1,1,3,3,3-d6)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate,monosodiumsalt
AA01EPS1
Submit
© 2017 AA BLOCKS, INC. All rights reserved.