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1800340-40-2,MFCD31544327
Catalog No.:AA01EO2L

1800340-40-2 | BMS-986158

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$139.00   $97.00
- +
5mg
≥98%
in stock  
$550.00   $385.00
- +
10mg
≥98%
in stock  
$960.00   $672.00
- +
25mg
≥98%
in stock  
$2,056.00   $1,439.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EO2L
Chemical Name:
BMS-986158
CAS Number:
1800340-40-2
Molecular Formula:
C30H33N5O2
Molecular Weight:
495.6153
MDL Number:
MFCD31544327
SMILES:
Cc1nnn(c1c1cnc2c(c1)n([C@H](c1ccccc1)C1CCOCC1)c1c2ccc(c1)C(O)(C)C)C
Properties
Computed Properties
 
Complexity:
769  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1

[2]Gavai,AshvinikumarV.;Norris,Derek;Delucca,George;Tortolani,David;Tokarski,JohnS.;Dodd,Dharmpal;O'Malley,Daniel;Zhao,Yufen;Quesnelle,Claude;Gill,Patrice;Vaccaro,Wayne;Huynh,Tram;Ahuja,Vijay;Han,Wen-Ching;Mussari,Christopher;Harikrishnan,Lalgudi;Kamau,Muthoni;Poss,Michael;Sheriff,Steven;Yan,Chunhong;Marsilio,Frank;Menard,Krista;Wen,Mei-Li;Rampulla,Richard;Wu,Dauh-Rurng;Li,Jianqing;Zhang,Huiping;Li,Peng;Sun,Dawn;Yip,Henry;Traeger,SarahC.;Zhang,Yingru;Mathur,Arvind;Zhang,Haiying;Huang,Christine;Yang,Zheng;Ranasinghe,Asoka;Everlof,Gerry;Raghavan,Nirmala;Tye,ChingKim;Wee,Susan;Hunt,JohnT.;Vite,Gregory;Westhouse,Richard;Lee,FrancisY.[JournalofMedicinalChemistry,2021,vol.64,#19,p.14247-14265]

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1

1800340-40-2   
CASUnavailable 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1Locationinpatent:Page/Pagecolumn342;343

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1

1800340-40-2   
CASUnavailable 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1Locationinpatent:Page/Pagecolumn421

Literature

Title: Yin M, et al. Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction. Nat Commun. 2020 Apr 14;11(1):1833.

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Tags:1800340-40-2 Molecular Formula|1800340-40-2 MDL|1800340-40-2 SMILES|1800340-40-2 BMS-986158
Catalog No.: AA01EO2L
1800340-40-2,MFCD31544327
1800340-40-2 | BMS-986158
Pack Size： 1mg
Purity： ≥98%
in stock
$139.00 $97.00
Pack Size： 5mg
Purity： ≥98%
in stock
$550.00 $385.00
Pack Size： 10mg
Purity： ≥98%
in stock
$960.00 $672.00
Pack Size： 25mg
Purity： ≥98%
in stock
$2,056.00 $1,439.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EO2L
Chemical Name: BMS-986158
CAS Number: 1800340-40-2
Molecular Formula: C30H33N5O2
Molecular Weight: 495.6153
MDL Number: MFCD31544327
SMILES: Cc1nnn(c1c1cnc2c(c1)n([C@H](c1ccccc1)C1CCOCC1)c1c2ccc(c1)C(O)(C)C)C
Properties
Complexity: 769  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 37  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.1  
Downstream Synthesis Route
1800345-33-8    1800340-40-2 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1

[2]Gavai,AshvinikumarV.;Norris,Derek;Delucca,George;Tortolani,David;Tokarski,JohnS.;Dodd,Dharmpal;O'Malley,Daniel;Zhao,Yufen;Quesnelle,Claude;Gill,Patrice;Vaccaro,Wayne;Huynh,Tram;Ahuja,Vijay;Han,Wen-Ching;Mussari,Christopher;Harikrishnan,Lalgudi;Kamau,Muthoni;Poss,Michael;Sheriff,Steven;Yan,Chunhong;Marsilio,Frank;Menard,Krista;Wen,Mei-Li;Rampulla,Richard;Wu,Dauh-Rurng;Li,Jianqing;Zhang,Huiping;Li,Peng;Sun,Dawn;Yip,Henry;Traeger,SarahC.;Zhang,Yingru;Mathur,Arvind;Zhang,Haiying;Huang,Christine;Yang,Zheng;Ranasinghe,Asoka;Everlof,Gerry;Raghavan,Nirmala;Tye,ChingKim;Wee,Susan;Hunt,JohnT.;Vite,Gregory;Westhouse,Richard;Lee,FrancisY.[JournalofMedicinalChemistry,2021,vol.64,#19,p.14247-14265]

1800340-40-2    1800341-94-9 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1

1800340-40-2   
CASUnavailable 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1Locationinpatent:Page/Pagecolumn342;343

1800340-40-2    1800344-40-4 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1

1800340-40-2   
CASUnavailable 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;UNIVERSITYOFHANNOVER-WO2015/100282,2015,A1Locationinpatent:Page/Pagecolumn421

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