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1695533-89-1,MFCD31657422
Catalog No.:AA01EO4K

1695533-89-1 | KO-947

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$199.00   $139.00
- +
10mg
≥98%
in stock  
$348.00   $243.00
- +
25mg
≥98%
in stock  
$762.00   $533.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EO4K
Chemical Name:
KO-947
CAS Number:
1695533-89-1
Molecular Formula:
C21H17N5O
Molecular Weight:
355.3926
MDL Number:
MFCD31657422
SMILES:
O=C1Nc2cc3[nH]nc(c3cc2CN1Cc1ccccc1)c1ccncc1
Properties
Computed Properties
 
Complexity:
531  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1Locationinpatent:Paragraph1237;1244

72521-00-7   
6-benzyl-3-(pyridin-4-yl)-1,5,6,8-tetrahydro-7H-pyrazolo4,3-gquinazolin-7-one 

[1]Patent:WO2015/51341,2015,A1

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1

Literature

Title: Burrows F, et al. KO-947, a potent ERK inhibitor with robust preclinical single agent activity in MAPK pathway dysregulated tumors [abstract In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5168. doi:10.1158/1538-7445.AM2017-5168.

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SDS
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Tags:1695533-89-1 Molecular Formula|1695533-89-1 MDL|1695533-89-1 SMILES|1695533-89-1 KO-947
Catalog No.: AA01EO4K
1695533-89-1,MFCD31657422
1695533-89-1 | KO-947
Pack Size： 1mg
Purity： ≥98%
in stock
$46.00 $32.00
Pack Size： 5mg
Purity： ≥98%
in stock
$199.00 $139.00
Pack Size： 10mg
Purity： ≥98%
in stock
$348.00 $243.00
Pack Size： 25mg
Purity： ≥98%
in stock
$762.00 $533.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EO4K
Chemical Name: KO-947
CAS Number: 1695533-89-1
Molecular Formula: C21H17N5O
Molecular Weight: 355.3926
MDL Number: MFCD31657422
SMILES: O=C1Nc2cc3[nH]nc(c3cc2CN1Cc1ccccc1)c1ccncc1
Properties
Complexity: 531  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 27  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.4  
Downstream Synthesis Route
1695537-68-8    1695533-89-1 

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1Locationinpatent:Paragraph1237;1244

72521-00-7   
6-benzyl-3-(pyridin-4-yl)-1,5,6,8-tetrahydro-7H-pyrazolo4,3-gquinazolin-7-one 

[1]Patent:WO2015/51341,2015,A1

1082040-69-4    1695533-89-1 

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1

1695537-77-9    1695533-89-1 

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1

1695537-64-4    1695533-89-1 

[1]CurrentPatentAssignee:KURAONCOLOGY,INC.-WO2015/51341,2015,A1

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