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Home Other Building Blocks 2089288-03-7
2089288-03-7,MFCD31619275
Catalog No.:AA01EO6J

2089288-03-7 | AZD1390

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$26.00   $18.00
- +
10mg
98%
in stock  
$135.00   $95.00
- +
25mg
98%
in stock  
$270.00   $189.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA01EO6J
Chemical Name:
AZD1390
CAS Number:
2089288-03-7
Molecular Formula:
C27H32FN5O2
Molecular Weight:
477.5737
MDL Number:
MFCD31619275
SMILES:
Fc1cc2ncc3c(c2cc1c1ccc(nc1)OCCCN1CCCCC1)n(C(C)C)c(=O)n3C
Properties
Computed Properties
 
Complexity:
720  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
7  
XLogP3:
4.2  

Literature

Title: Durant ST, et al. The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models. Sci Adv. 2018 Jun 20;4(6):eaat1719.

Title: J. Kahn, et al. Next-Generation ATM Kinase Inhibitors Under Development Radiosensitize Glioblastoma With Conformal Radiation in a Mouse Orthotopic Model. IJROBP. 2017. 99, 600-601.

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SDS
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Tags:2089288-03-7 Molecular Formula|2089288-03-7 MDL|2089288-03-7 SMILES|2089288-03-7 AZD1390