+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 2060571-02-8
2060571-02-8,MFCD31382124
Catalog No.:AA01EO7S

2060571-02-8 | GDC-0077

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$290.00   $203.00
- +
5mg
95%
1 week  
$530.00   $371.00
- +
10mg
95%
1 week  
$829.00   $580.00
- +
25mg
95%
1 week  
$1,170.00   $819.00
- +
50mg
95%
1 week  
$1,692.00   $1,184.00
- +
100mg
95%
1 week  
$2,263.00   $1,584.00
- +
200mg
95%
1 week  
$3,018.00   $2,112.00
- +
500mg
95%
1 week  
$4,480.00   $3,136.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO7S
Chemical Name:
GDC-0077
CAS Number:
2060571-02-8
Molecular Formula:
C18H19F2N5O4
Molecular Weight:
407.3714
MDL Number:
MFCD31382124
SMILES:
NC(=O)[C@@H](Nc1ccc2c(c1)OCCn1c2nc(c1)N1C(=O)OC[C@H]1C(F)F)C
Properties
Computed Properties
 
Complexity:
641  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
1.5  

Literature

Title: R Hong, Abstract PD4-14: GDC-0077 is a selective PI3Kalpha inhibitor that demonstrates robust efficacy in PIK3CA mutant breast cancer models as a single agent and in combination with standard of care therapies. 2017 San Antonio Breast Cancer Symposium.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 2060571-02-8
Building Blocks
More >
Tags:2060571-02-8 Molecular Formula|2060571-02-8 MDL|2060571-02-8 SMILES|2060571-02-8 GDC-0077