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1629063-81-5,MFCD31721018
Catalog No.:AA01EOFK

1629063-81-5 | GNE-131

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$227.00   $159.00
- +
5mg
95%
1 week  
$483.00   $338.00
- +
10mg
95%
1 week  
$671.00   $470.00
- +
25mg
95%
1 week  
$1,051.00   $736.00
- +
50mg
95%
1 week  
$1,418.00   $992.00
- +
100mg
95%
1 week  
$1,875.00   $1,312.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EOFK
Chemical Name:
GNE-131
CAS Number:
1629063-81-5
Molecular Formula:
C23H30N4O3S
Molecular Weight:
442.5743
MDL Number:
MFCD31721018
SMILES:
O=S(=O)(C1CC1)Nc1nnc2n1cc(C1CC1)c(c2)OCC12C[C@@H]3C[C@H](C2)C[C@H](C1)C3
Properties
Computed Properties
 
Complexity:
780  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
4.8  

Literature

Title: Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa(V)1.7 Inhibitors for the Treatment of Pain.

Journal: Journal of medicinal chemistry 20180614

Title: Focken T, et al. Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-(,2,4Triazolo,3- apyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. J Med Chem. 2018 Jun 14;61(11):4810-4831.

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Tags:1629063-81-5 Molecular Formula|1629063-81-5 MDL|1629063-81-5 SMILES|1629063-81-5 GNE-131
Catalog No.: AA01EOFK
1629063-81-5,MFCD31721018
1629063-81-5 | GNE-131
Pack Size： 1mg
Purity： 95%
1 week
$227.00 $159.00
Pack Size： 5mg
Purity： 95%
1 week
$483.00 $338.00
Pack Size： 10mg
Purity： 95%
1 week
$671.00 $470.00
Pack Size： 25mg
Purity： 95%
1 week
$1,051.00 $736.00
Pack Size： 50mg
Purity： 95%
1 week
$1,418.00 $992.00
Pack Size： 100mg
Purity： 95%
1 week
$1,875.00 $1,312.00
Quantity
- +
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bulk Quotation Request
Technical Information
Catalog Number: AA01EOFK
Chemical Name: GNE-131
CAS Number: 1629063-81-5
Molecular Formula: C23H30N4O3S
Molecular Weight: 442.5743
MDL Number: MFCD31721018
SMILES: O=S(=O)(C1CC1)Nc1nnc2n1cc(C1CC1)c(c2)OCC12C[C@@H]3C[C@H](C2)C[C@H](C1)C3
Properties
Complexity: 780  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 31  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 7  
XLogP3: 4.8  
Literature fold

Title: Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa(V)1.7 Inhibitors for the Treatment of Pain.

Journal: Journal of medicinal chemistry20180614

Title: Focken T, et al. Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-(,2,4Triazolo,3- apyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. J Med Chem. 2018 Jun 14;61(11):4810-4831.

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