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Home Other Building Blocks 2095704-43-9
2095704-43-9,MFCD31728203
Catalog No.:AA01EOFZ

2095704-43-9 | SLV-2436

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$12.00   $8.00
- +
5mg
97%
in stock  
$27.00   $19.00
- +
10mg
97%
in stock  
$39.00   $28.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EOFZ
Chemical Name:
SLV-2436
CAS Number:
2095704-43-9
Molecular Formula:
C19H15ClN4O
Molecular Weight:
350.8016
MDL Number:
MFCD31728203
SMILES:
Clc1cccc(c1)Cn1cc(ccc1=O)c1ccc2c(c1)[nH]nc2N
Properties
Computed Properties
 
Complexity:
578  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
3  

Downstream Synthesis Route

[1]Dreas,Agnieszka;Kucwaj-Brysz,Katarzyna;Pyziak,Karolina;Kulesza,Urszula;Wincza,Ewelina;Fabritius,Charles-Henry;Michalik,Kinga;Gabor-Worwa,Ewelina;Gołas,Aniela;Milik,Mariusz;Masiejczyk,Magdalena;Majewska,Eliza;Pyśniak,Kazimiera;Wójcik-Trechcińska,Urszula;Sandowska-Markiewicz,Zuzanna;Brzózka,Krzysztof;Ostrowski,Jerzy;Rzymski,Tomasz;Mikula,Michal[EuropeanJournalofMedicinalChemistry,2021,vol.213]

[1]Dreas,Agnieszka;Kucwaj-Brysz,Katarzyna;Pyziak,Karolina;Kulesza,Urszula;Wincza,Ewelina;Fabritius,Charles-Henry;Michalik,Kinga;Gabor-Worwa,Ewelina;Gołas,Aniela;Milik,Mariusz;Masiejczyk,Magdalena;Majewska,Eliza;Pyśniak,Kazimiera;Wójcik-Trechcińska,Urszula;Sandowska-Markiewicz,Zuzanna;Brzózka,Krzysztof;Ostrowski,Jerzy;Rzymski,Tomasz;Mikula,Michal[EuropeanJournalofMedicinalChemistry,2021,vol.213]

[1]Dreas,Agnieszka;Kucwaj-Brysz,Katarzyna;Pyziak,Karolina;Kulesza,Urszula;Wincza,Ewelina;Fabritius,Charles-Henry;Michalik,Kinga;Gabor-Worwa,Ewelina;Gołas,Aniela;Milik,Mariusz;Masiejczyk,Magdalena;Majewska,Eliza;Pyśniak,Kazimiera;Wójcik-Trechcińska,Urszula;Sandowska-Markiewicz,Zuzanna;Brzózka,Krzysztof;Ostrowski,Jerzy;Rzymski,Tomasz;Mikula,Michal[EuropeanJournalofMedicinalChemistry,2021,vol.213]

Literature

Title: Zhan Y, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma. J Clin Invest. 2017 Nov 1;127(11):4179-4192.

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