+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
1883423-59-3,MFCD31382190
Catalog No.:AA01EOND

1883423-59-3 | MSC2530818

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$13.00   $9.00
- +
10mg
98+%
in stock  
$43.00   $31.00
- +
250mg
97%
in stock  
$805.00   $564.00
- +
1g
97%
in stock  
$1,997.00 $1,398.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EOND
Chemical Name:
MSC2530818
CAS Number:
1883423-59-3
Molecular Formula:
C18H17ClN4O
Molecular Weight:
340.8068
MDL Number:
MFCD31382190
SMILES:
Clc1ccc(cc1)[C@@H]1CCCN1C(=O)c1cnc2c(c1)c(C)n[nH]2
Properties
Computed Properties
 
Complexity:
468  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:CANCERRESEARCHUK;MERCKKGAA-WO2016/26549,2016,A1

[1]CurrentPatentAssignee:CANCERRESEARCHUK;MERCKKGAA-WO2016/26549,2016,A1

[1]CurrentPatentAssignee:CANCERRESEARCHUK;MERCKKGAA-WO2016/26549,2016,A1Locationinpatent:Page/Pagecolumn30

1118787-14-6    1228560-89-1   
(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl-(3-methyl-1H-pyrazolo-3,4-bpyridin-5-yl)methanone 

[1]JournalofMedicinalChemistry,2016,vol.59,p.9337-9349

1118787-14-6    1217651-75-6   
(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl-(3-methyl-1H-pyrazolo-3,4-bpyridin-5-yl)methanone 

[1],2020,vol.6,p.781-791

Literature

Title: Czodrowski P, et al. Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening. J Med Chem. 2016 Oct 27;59(20):9337-9349.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 1883423-59-3
Building Blocks
More >
Tags:1883423-59-3 Molecular Formula|1883423-59-3 MDL|1883423-59-3 SMILES|1883423-59-3 MSC2530818
Catalog No.: AA01EOND
1883423-59-3,MFCD31382190
1883423-59-3 | MSC2530818
Pack Size： 1mg
Purity： 98+%
in stock
$13.00 $9.00
Pack Size： 10mg
Purity： 98+%
in stock
$43.00 $31.00
Pack Size： 250mg
Purity： 97%
in stock
$805.00 $564.00
Pack Size： 1g
Purity： 97%
in stock
$1,997.00 $1,398.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EOND
Chemical Name: MSC2530818
CAS Number: 1883423-59-3
Molecular Formula: C18H17ClN4O
Molecular Weight: 340.8068
MDL Number: MFCD31382190
SMILES: Clc1ccc(cc1)[C@@H]1CCCN1C(=O)c1cnc2c(c1)c(C)n[nH]2
Properties
Complexity: 468  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 24  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.3  
Downstream Synthesis Route
1150618-05-5    1883423-59-3    1883423-60-6 

[1]CurrentPatentAssignee:CANCERRESEARCHUK;MERCKKGAA-WO2016/26549,2016,A1

1118787-14-6    1883423-59-3    1883423-60-6 

[1]CurrentPatentAssignee:CANCERRESEARCHUK;MERCKKGAA-WO2016/26549,2016,A1

1883423-56-0    1883423-59-3    1883423-60-6 

[1]CurrentPatentAssignee:CANCERRESEARCHUK;MERCKKGAA-WO2016/26549,2016,A1Locationinpatent:Page/Pagecolumn30

1118787-14-6    1228560-89-1   
(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl-(3-methyl-1H-pyrazolo-3,4-bpyridin-5-yl)methanone 

[1]JournalofMedicinalChemistry,2016,vol.59,p.9337-9349

1118787-14-6    1217651-75-6   
(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl-(3-methyl-1H-pyrazolo-3,4-bpyridin-5-yl)methanone 

[1],2020,vol.6,p.781-791

Related Products of of 1883423-59-3
Building Blocks More >
1427521-36-5
1427521-36-5
3-[(4-ethyl-1-naphthalenyl)carbonyl]-1H-indole-1-pentanoicacid
AA01EOUO
1859218-30-6
1859218-30-6
1-(5-fluoropentyl)-1H-indole
AA01EP3E
41232-97-7
41232-97-7
2-methyl-3-phenyl-2-oxiranecarboxylicacid,ethylester
AA01EPDB | MFCD00455318
1188890-32-5
1188890-32-5
3-[4-(4-morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol,dihydrochloride
AA01EPJP | MFCD24368998
1638677-49-2
1638677-49-2
1-(1-methyl-1H-indol-3-yl)-2-(1-naphthalenyl)-ethanone
AA01EPPG
2011762-82-4
2011762-82-4
N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl-d3]-octadecanamide
AA01EPWE
1000672-89-8
1000672-89-8
2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl-pyrazine
AA01EQ5V
870998-13-3
870998-13-3
CXCR3Antagonist6c-Compound6c
AA01EQC8 | MFCD22123246
111198-06-2
111198-06-2
1-(1H-1,2,3-Benzotriazol-1-ylmethyl)pyridin-1-ium chloride
AA01EQOG | MFCD00957735
127856-69-3
127856-69-3
1,3-Diethyl 2-(pyren-1-ylmethyl)propanedioate
AA01ERJS | MFCD00963771
Submit
© 2017 AA BLOCKS, INC. All rights reserved.