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408303-43-5
Catalog No.:AA01FPC0

408303-43-5 | GW 766994

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$262.00   $183.00
- +
5mg
≥98%
in stock  
$1,165.00   $815.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01FPC0
Chemical Name:
GW 766994
CAS Number:
408303-43-5
Molecular Formula:
C21H24Cl2N4O3
Molecular Weight:
451.3463
SMILES:
O=C(NCc1ccc(cc1)C(=O)N)NC[C@@H]1OCCN(C1)Cc1ccc(c(c1)Cl)Cl
Properties
Computed Properties
 
Complexity:
575  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.2  

Literature

Title: Neighbour H, et al. Safety and efficacy of an oral CCR3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo-controlled clinical trial. Clin Exp Allergy. 2014 Apr;44(4):508-16.

Title: Zhu C, et al. Targeting CCR3 to Reduce Amyloid-β Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2017 Dec;54(10):7964-7978.

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Tags:408303-43-5 Molecular Formula|408303-43-5 MDL|408303-43-5 SMILES|408303-43-5 GW 766994
Catalog No.: AA01FPC0
408303-43-5
408303-43-5 | GW 766994
Pack Size： 1mg
Purity： ≥98%
in stock
$262.00 $183.00
Pack Size： 5mg
Purity： ≥98%
in stock
$1,165.00 $815.00
Quantity
- +
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bulk Quotation Request
Technical Information
Catalog Number: AA01FPC0
Chemical Name: GW 766994
CAS Number: 408303-43-5
Molecular Formula: C21H24Cl2N4O3
Molecular Weight: 451.3463
SMILES: O=C(NCc1ccc(cc1)C(=O)N)NC[C@@H]1OCCN(C1)Cc1ccc(c(c1)Cl)Cl
Properties
Complexity: 575  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 30  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 1  
XLogP3: 2.2  
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