101303-98-4,MFCD20488057
Catalog No.:AA009RX4

101303-98-4 | Zacopride hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
97%
in stock  
$250.00   $175.00
- +
10mg
97%
in stock  
$375.00   $263.00
- +
25mg
97%
in stock  
$693.00   $485.00
- +
50mg
97%
in stock  
$1,082.00   $758.00
- +
100mg
97%
in stock  
$1,682.00   $1,178.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA009RX4
Chemical Name:
Zacopride hydrochloride
CAS Number:
101303-98-4
Molecular Formula:
C15H21Cl2N3O2
Molecular Weight:
346.2521
MDL Number:
MFCD20488057
SMILES:
COc1cc(N)c(cc1C(=O)N[C@@H]1CN2CC[C@H]1CC2)Cl.Cl
Properties
Computed Properties
 
Complexity:
387  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  

Literature

Title: A novel discovery of IK1 channel agonist: zacopride selectively enhances IK1 current and suppresses triggered arrhythmias in the rat.

Journal: Journal of cardiovascular pharmacology 20120101

Title: Reduced signal transduction by 5-HT4 receptors after long-term venlafaxine treatment in rats.

Journal: British journal of pharmacology 20101001

Title: Investigations into the binding affinities of different human 5-HT4 receptor splice variants.

Journal: Pharmacology 20100101

Title: Imipramine and citalopram reverse corticosterone-induced alterations in the effects of the activation of 5-HT(1A) and 5-HT(2) receptors in rat frontal cortex.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060901

Title: Imipramine treatment ameliorates corticosterone-induced alterations in the effects of 5-HT1A and 5-HT4 receptor activation in the CA1 area of rat hippocampus.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701

Title: Inhibitory effect of zacopride on Cisplatin-induced delayed emesis in ferrets.

Journal: Journal of pharmacological sciences 20060501

Title: Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060201

Title: Antinociception: mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component.

Journal: European journal of pharmacology 20051228

Title: Effect of ginseng saponins on a rat visceral hypersensitivity model.

Journal: Biological & pharmaceutical bulletin 20051101

Title: 5-HT(3) receptors, alcohol and aggressive behavior in mice.

Journal: Behavioural pharmacology 20050501

Title: MD-354 potentiates the antinociceptive effect of clonidine in the mouse tail-flick but not hot-plate assay.

Journal: European journal of pharmacology 20040714

Title: Adaptive changes in the reactivity of 5-HT1A and 5-HT2 receptors induced in rat frontal cortex by repeated imipramine and citalopram.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030501

Title: Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats.

Journal: Psychopharmacology 20030101

Title: Comparison of the effects of 5-HT1A and 5-HT4 receptor activation on field potentials and epileptiform activity in rat hippocampus.

Journal: Experimental brain research 20021201

Title: Imipramine but not 5-HT(1A) receptor agonists or neuroleptics induces adaptive changes in hippocampal 5-HT(1A) and 5-HT(4) receptors.

Journal: European journal of pharmacology 20020517

Title: Opposite effects of antidepressants and corticosterone on the sensitivity of hippocampal CA1 neurons to 5-HT1A and 5-HT4 receptor activation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010501

Title: R-zacopride, a 5-HT3 antagonist/5-HT4 agonist, reduces sleep apneas in rats.

Journal: Pharmacology, biochemistry, and behavior 20010101

Title: Anxiolytic-like effects of DAIZAC, a selective high-affinity 5-HT(3) receptor antagonist, in the mouse elevated plus-maze.

Journal: Pharmacology, biochemistry, and behavior 20010101

Title: Autoradiographic distribution of [3H]-(S)-zacopride-labelled 5-HT3 receptors in human brain.

Journal: Journal of the neurological sciences 19961201

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SDS
Historical Records
Tags:101303-98-4 Molecular Formula|101303-98-4 MDL|101303-98-4 SMILES|101303-98-4 Zacopride hydrochloride
Catalog No.: AA009RX4
101303-98-4,MFCD20488057
101303-98-4 | Zacopride hydrochloride
Pack Size: 5mg
Purity: 97%
in stock
$250.00 $175.00
Pack Size: 10mg
Purity: 97%
in stock
$375.00 $263.00
Pack Size: 25mg
Purity: 97%
in stock
$693.00 $485.00
Pack Size: 50mg
Purity: 97%
in stock
$1,082.00 $758.00
Pack Size: 100mg
Purity: 97%
in stock
$1,682.00 $1,178.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA009RX4
Chemical Name: Zacopride hydrochloride
CAS Number: 101303-98-4
Molecular Formula: C15H21Cl2N3O2
Molecular Weight: 346.2521
MDL Number: MFCD20488057
SMILES: COc1cc(N)c(cc1C(=O)N[C@@H]1CN2CC[C@H]1CC2)Cl.Cl
Properties
Complexity: 387  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 22  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: A novel discovery of IK1 channel agonist: zacopride selectively enhances IK1 current and suppresses triggered arrhythmias in the rat.

Journal: Journal of cardiovascular pharmacology20120101

Title: Reduced signal transduction by 5-HT4 receptors after long-term venlafaxine treatment in rats.

Journal: British journal of pharmacology20101001

Title: Investigations into the binding affinities of different human 5-HT4 receptor splice variants.

Journal: Pharmacology20100101

Title: Imipramine and citalopram reverse corticosterone-induced alterations in the effects of the activation of 5-HT(1A) and 5-HT(2) receptors in rat frontal cortex.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20060901

Title: Imipramine treatment ameliorates corticosterone-induced alterations in the effects of 5-HT1A and 5-HT4 receptor activation in the CA1 area of rat hippocampus.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20060701

Title: Inhibitory effect of zacopride on Cisplatin-induced delayed emesis in ferrets.

Journal: Journal of pharmacological sciences20060501

Title: Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20060201

Title: Antinociception: mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component.

Journal: European journal of pharmacology20051228

Title: Effect of ginseng saponins on a rat visceral hypersensitivity model.

Journal: Biological & pharmaceutical bulletin20051101

Title: 5-HT(3) receptors, alcohol and aggressive behavior in mice.

Journal: Behavioural pharmacology20050501

Title: MD-354 potentiates the antinociceptive effect of clonidine in the mouse tail-flick but not hot-plate assay.

Journal: European journal of pharmacology20040714

Title: Adaptive changes in the reactivity of 5-HT1A and 5-HT2 receptors induced in rat frontal cortex by repeated imipramine and citalopram.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20030501

Title: Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats.

Journal: Psychopharmacology20030101

Title: Comparison of the effects of 5-HT1A and 5-HT4 receptor activation on field potentials and epileptiform activity in rat hippocampus.

Journal: Experimental brain research20021201

Title: Imipramine but not 5-HT(1A) receptor agonists or neuroleptics induces adaptive changes in hippocampal 5-HT(1A) and 5-HT(4) receptors.

Journal: European journal of pharmacology20020517

Title: Opposite effects of antidepressants and corticosterone on the sensitivity of hippocampal CA1 neurons to 5-HT1A and 5-HT4 receptor activation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20010501

Title: R-zacopride, a 5-HT3 antagonist/5-HT4 agonist, reduces sleep apneas in rats.

Journal: Pharmacology, biochemistry, and behavior20010101

Title: Anxiolytic-like effects of DAIZAC, a selective high-affinity 5-HT(3) receptor antagonist, in the mouse elevated plus-maze.

Journal: Pharmacology, biochemistry, and behavior20010101

Title: Autoradiographic distribution of [3H]-(S)-zacopride-labelled 5-HT3 receptors in human brain.

Journal: Journal of the neurological sciences19961201

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