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1050500-29-2,MFCD17215204
Catalog No.:AA008TAS

1050500-29-2 | AST-1306

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$82.00   $57.00
- +
5mg
>98% (or refer to the Certificate of Analysis)
in stock  
$325.00   $228.00
- +
10mg
>98% (or refer to the Certificate of Analysis)
in stock  
$504.00   $353.00
- +
25mg
>98% (or refer to the Certificate of Analysis)
in stock  
$861.00   $603.00
- +
50mg
>98% (or refer to the Certificate of Analysis)
in stock  
$1,397.00   $978.00
- +
100mg
>98% (or refer to the Certificate of Analysis)
in stock  
$2,290.00   $1,603.00
- +
200mg
>98% (or refer to the Certificate of Analysis)
in stock  
$4,075.00   $2,853.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TAS
Chemical Name:
AST-1306
CAS Number:
1050500-29-2
Molecular Formula:
C31H26ClFN4O5S
Molecular Weight:
621.0783
MDL Number:
MFCD17215204
SMILES:
Cc1ccc(cc1)S(=O)(=O)O.C=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc1ccc(c(c1)Cl)OCc1cccc(c1)F
Properties
Computed Properties
 
Complexity:
848  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: A phase I study of AST1306, a novel irreversible EGFR and HER2 kinase inhibitor, in patients with advanced solid tumors.

Journal: Journal of hematology & oncology 20140101

Title: AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo.

Journal: PloS one 20110101

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SDS
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2171313-64-5

2171313-64-5
Tags:1050500-29-2 Molecular Formula|1050500-29-2 MDL|1050500-29-2 SMILES|1050500-29-2 AST-1306
Catalog No.: AA008TAS
1050500-29-2,MFCD17215204
1050500-29-2 | AST-1306
Pack Size： 1mg
Purity： ≥98%
in stock
$82.00 $57.00
Pack Size： 5mg
Purity： >98% (or refer to the Certificate of Analysis)
in stock
$325.00 $228.00
Pack Size： 10mg
Purity： >98% (or refer to the Certificate of Analysis)
in stock
$504.00 $353.00
Pack Size： 25mg
Purity： >98% (or refer to the Certificate of Analysis)
in stock
$861.00 $603.00
Pack Size： 50mg
Purity： >98% (or refer to the Certificate of Analysis)
in stock
$1,397.00 $978.00
Pack Size： 100mg
Purity： >98% (or refer to the Certificate of Analysis)
in stock
$2,290.00 $1,603.00
Pack Size： 200mg
Purity： >98% (or refer to the Certificate of Analysis)
in stock
$4,075.00 $2,853.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008TAS
Chemical Name: AST-1306
CAS Number: 1050500-29-2
Molecular Formula: C31H26ClFN4O5S
Molecular Weight: 621.0783
MDL Number: MFCD17215204
SMILES: Cc1ccc(cc1)S(=O)(=O)O.C=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc1ccc(c(c1)Cl)OCc1cccc(c1)F
Properties
Complexity: 848  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 43  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: A phase I study of AST1306, a novel irreversible EGFR and HER2 kinase inhibitor, in patients with advanced solid tumors.

Journal: Journal of hematology & oncology20140101

Title: AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo.

Journal: PloS one20110101

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