107-91-5,MFCD00008024
Catalog No.:AA003376

107-91-5 | 2-Cyanoacetamide

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Purity
Availability
Price(USD)
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25g
97%
in stock  
$12.00   $8.00
- +
100g
98%
in stock  
$36.00   $25.00
- +
250g
≥ 99% (GC)
in stock  
$74.00   $52.00
- +
500g
>98%(GC)
in stock  
$86.00   $60.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003376
Chemical Name:
2-Cyanoacetamide
CAS Number:
107-91-5
Molecular Formula:
C3H4N2O
Molecular Weight:
84.0767
MDL Number:
MFCD00008024
SMILES:
NC(=O)CC#N
Properties
Properties
 
BP:
351.2 °C at 760 mmHg  
Form:
Solid  
MP:
119-121 °C  
Refractive Index:
1.5110 (estimate)  
Solubility:
cold water: soluble1gm in 6.5ml  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
98.6  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1  

Literature

Title: Regiochemistry of the condensation of 2-aroyl-cyclohexanones and 2-cyanoacetamide: 13C-labeling studies and semiempirical MO calculations.

Journal: The Journal of organic chemistry 20120907

Title: Simultaneous determination of uronates found in polysaccharides from natural products by HPLC with fluorometric detection.

Journal: Carbohydrate research 20120901

Title: 2-(4-Chloro-3,3,7-trimethyl-2,3-dihydro-1H-indol-2-yl-idene)-2-cyano-acetamide.

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: Determination of idebenone in plasma by HPLC with post-column fluorescence derivatization using 2-cyanoacetamide.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: Isolation and characterization of Kluyvera georgiana strain with the potential for acrylamide biodegradation.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

Title: Determination of ubiquinone in blood by high-performance liquid chromatography with post-column fluorescence derivatization using 2-cyanoacetamide.

Journal: Journal of fluorescence 20111101

Title: A convenient synthesis of novel pyranosyl homo-C-nucleosides and their antidiabetic activities.

Journal: Carbohydrate research 20110715

Title: Synthesis of functionalized 2-aminohydropyridines and 2-pyridinones via domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and substituted acetonitriles.

Journal: ACS combinatorial science 20110711

Title: Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.

Journal: Molecules (Basel, Switzerland) 20110504

Title: Microdetermination of hyaluronan in human plasma by high-performance liquid chromatography with a graphitized carbon column and postcolumn fluorometric detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415

Title: High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase.

Journal: PLoS neglected tropical diseases 20110401

Title: A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates.

Journal: Organic & biomolecular chemistry 20110307

Title: Spectrofluorimetric method for determination and validation of cefixime in pharmaceutical preparations through derivatization with 2-cyanoacetamide.

Journal: Journal of fluorescence 20110301

Title: Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.

Journal: Molecular diversity 20110201

Title: Diversity-oriented synthesis of spiro-substituted 1,3-thiazine library via a one-pot, two-step, three-component reaction.

Journal: ACS combinatorial science 20110110

Title: Biodegradation of acrylamide by Enterobacter aerogenes isolated from wastewater in Thailand.

Journal: Journal of environmental sciences (China) 20110101

Title: Infrared assisted production of 3,4-dihydro-2(1H)-pyridones in solvent-free conditions.

Journal: International journal of molecular sciences 20110101

Title: Synthesis of new pyrimidine derivatives with evaluation of their anti-inflammatory and analgesic activities.

Journal: Acta poloniae pharmaceutica 20110101

Title: Novel synthesis and antitumor evaluation of polyfunctionally substituted heterocyclic compounds derived from 2-cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide.

Journal: Molecules (Basel, Switzerland) 20101227

Title: Recovery of heat shock-triggered released apoplastic Ca2+ accompanied by pectin methylesterase activity is required for thermotolerance in soybean seedlings.

Journal: Journal of experimental botany 20100601

Title: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes.

Journal: Organic letters 20100521

Title: Cyanoacetamide MCR (III): three-component Gewald reactions revisited.

Journal: Journal of combinatorial chemistry 20100101

Title: Automated saccharification assay for determination of digestibility in plant materials.

Journal: Biotechnology for biofuels 20100101

Title: Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines.

Journal: European journal of medicinal chemistry 20090901

Title: A simplified green chemistry approaches to synthesis of 2-substituted 1,2,3-triazoles and 4-amino-5-cyanopyrazole derivatives conventional heating versus microwave and ultrasound as ecofriendly energy sources.

Journal: Ultrasonics sonochemistry 20090801

Title: Cyanoacetamide multicomponent reaction (I): Parallel synthesis of cyanoacetamides.

Journal: Journal of combinatorial chemistry 20090101

Title: A concise approach to a gelsemine core structure using an oxygen to carbon bridge swapping strategy.

Journal: Organic letters 20081106

Title: Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety.

Journal: European journal of medicinal chemistry 20081001

Title: Synthesis and antimicrobial activity of some new pyrazole, fused pyrazolo[3,4-d]-pyrimidine and pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine derivatives.

Journal: Molecules (Basel, Switzerland) 20080729

Title: Spectrofluorimetric determination of oxamniquine in dosage forms and spiked human plasma through derivatization with 1-dimethylaminonaphthalene-5-sulphonyl chloride.

Journal: Journal of fluorescence 20080301

Title: Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection.

Journal: Arthritis research & therapy 20080101

Title: A one-step fusion of 1,3-thiazine and pyrimidine cycles.

Journal: Organic letters 20071011

Title: Chiral salen-aluminum complex as a catalyst for enantioselective alpha-addition of isocyanides to aldehydes: asymmetric synthesis of 2-(1-hydroxyalkyl)-5-aminooxazoles.

Journal: Organic letters 20070830

Title: HPLC determination of chondrosine in mouse blood plasma after intravenous or oral dose.

Journal: Biological & pharmaceutical bulletin 20070801

Title: Total synthesis of anibamine, a novel natural product as a chemokine receptor CCR5 antagonist.

Journal: Organic letters 20070510

Title: The tert-amino effect in heterocyclic chemistry: synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives.

Journal: Beilstein journal of organic chemistry 20070101

Title: Substituted 2-methylene-1,3-oxazolidines, -1,3-thiazolidines, -1,3-benzothiazines, -1,3-oxazines, and substituted imidazopyrimidinediones from Cl(CH2)nNCO and Cl(CH2)nNCS and active methylene compounds.

Journal: The Journal of organic chemistry 20061222

Title: Synthesis and evaluation of 2,6-piperidinedione derivatives as potentially novel compounds with analgesic and other CNS activities.

Journal: Inflammopharmacology 20060301

Title: Improved quality control of [18F]FDG by HPLC with UV detection.

Journal: Nuclear medicine and biology 20051101

Title: Separation of keratan-sulfate-derived disaccharides by high-performance liquid chromatography and postcolumn derivatization with 2-cyanoacetamide and fluorimetric detection.

Journal: Analytical biochemistry 20050715

Title: Microdetermination of chondroitin sulfate in normal human plasma by fluorophore-assisted carbohydrate electrophoresis (FACE).

Journal: Clinica chimica acta; international journal of clinical chemistry 20050601

Title: Synthesis of new iso-C-nucleoside analogues from 2-(methyl 2-O-benzyl-4,6-O-benzylidene-3-deoxy-alpha-D-altropyranosid-3-yl)ethanal.

Journal: Carbohydrate research 20050321

Title: Characterization of heparan sulfate from the unossified antler of Cervus elaphus.

Journal: Carbohydrate research 20050227

Title: Structural variations of piritrexim, a lipophilic inhibitor of human dihydrofolate reductase: synthesis, antitumor activity and molecular modeling investigations.

Journal: European journal of medicinal chemistry 20041201

Title: Separation of capsular polysaccharide-K4- and defructosylated-K4-derived disaccharides by high-performance liquid chromatography and postcolumn derivatization with 2-cyanoacetamide and fluorimetric detection.

Journal: Analytical biochemistry 20040715

Title: Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.

Journal: Microbiology (Reading, England) 20040401

Title: 2-pyridones from cyanoacetamides and enecarbonyl compounds: application to the synthesis of nothapodytine B.

Journal: The Journal of organic chemistry 20020614

Title: Conductivity detection for molecular mass estimation of per-O-sulfonated glycosaminoglycans separated by high-performance size-exclusion chromatography.

Journal: Journal of chromatography. A 20020614

Title: In vitro and in vivo anti-Trypanosoma cruzi activity of a novel nitro-derivative.

Journal: Memorias do Instituto Oswaldo Cruz 20020601

Title: Pretreatment procedure for the microdetermination of chondroitin sulfate in plasma and urine.

Journal: Analytical biochemistry 20020315

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SDS
Tags:107-91-5 Molecular Formula|107-91-5 MDL|107-91-5 SMILES|107-91-5 2-Cyanoacetamide
Catalog No.: AA003376
107-91-5,MFCD00008024
107-91-5 | 2-Cyanoacetamide
Pack Size: 25g
Purity: 97%
in stock
$12.00 $8.00
Pack Size: 100g
Purity: 98%
in stock
$36.00 $25.00
Pack Size: 250g
Purity: ≥ 99% (GC)
in stock
$74.00 $52.00
Pack Size: 500g
Purity: >98%(GC)
in stock
$86.00 $60.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA003376
Chemical Name: 2-Cyanoacetamide
CAS Number: 107-91-5
Molecular Formula: C3H4N2O
Molecular Weight: 84.0767
MDL Number: MFCD00008024
SMILES: NC(=O)CC#N
Properties
BP: 351.2 °C at 760 mmHg  
Form: Solid  
MP: 119-121 °C  
Refractive Index: 1.5110 (estimate)  
Solubility: cold water: soluble1gm in 6.5ml  
Storage: Keep in dry area;Room Temperature;  
Complexity: 98.6  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 6  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1  
Literature fold

Title: Regiochemistry of the condensation of 2-aroyl-cyclohexanones and 2-cyanoacetamide: 13C-labeling studies and semiempirical MO calculations.

Journal: The Journal of organic chemistry20120907

Title: Simultaneous determination of uronates found in polysaccharides from natural products by HPLC with fluorometric detection.

Journal: Carbohydrate research20120901

Title: 2-(4-Chloro-3,3,7-trimethyl-2,3-dihydro-1H-indol-2-yl-idene)-2-cyano-acetamide.

Journal: Acta crystallographica. Section E, Structure reports online20120101

Title: Determination of idebenone in plasma by HPLC with post-column fluorescence derivatization using 2-cyanoacetamide.

Journal: Chemical & pharmaceutical bulletin20120101

Title: Isolation and characterization of Kluyvera georgiana strain with the potential for acrylamide biodegradation.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering20120101

Title: Determination of ubiquinone in blood by high-performance liquid chromatography with post-column fluorescence derivatization using 2-cyanoacetamide.

Journal: Journal of fluorescence20111101

Title: A convenient synthesis of novel pyranosyl homo-C-nucleosides and their antidiabetic activities.

Journal: Carbohydrate research20110715

Title: Synthesis of functionalized 2-aminohydropyridines and 2-pyridinones via domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and substituted acetonitriles.

Journal: ACS combinatorial science20110711

Title: Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.

Journal: Molecules (Basel, Switzerland)20110504

Title: Microdetermination of hyaluronan in human plasma by high-performance liquid chromatography with a graphitized carbon column and postcolumn fluorometric detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20110415

Title: High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase.

Journal: PLoS neglected tropical diseases20110401

Title: A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates.

Journal: Organic & biomolecular chemistry20110307

Title: Spectrofluorimetric method for determination and validation of cefixime in pharmaceutical preparations through derivatization with 2-cyanoacetamide.

Journal: Journal of fluorescence20110301

Title: Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.

Journal: Molecular diversity20110201

Title: Diversity-oriented synthesis of spiro-substituted 1,3-thiazine library via a one-pot, two-step, three-component reaction.

Journal: ACS combinatorial science20110110

Title: Biodegradation of acrylamide by Enterobacter aerogenes isolated from wastewater in Thailand.

Journal: Journal of environmental sciences (China)20110101

Title: Infrared assisted production of 3,4-dihydro-2(1H)-pyridones in solvent-free conditions.

Journal: International journal of molecular sciences20110101

Title: Synthesis of new pyrimidine derivatives with evaluation of their anti-inflammatory and analgesic activities.

Journal: Acta poloniae pharmaceutica20110101

Title: Novel synthesis and antitumor evaluation of polyfunctionally substituted heterocyclic compounds derived from 2-cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide.

Journal: Molecules (Basel, Switzerland)20101227

Title: Recovery of heat shock-triggered released apoplastic Ca2+ accompanied by pectin methylesterase activity is required for thermotolerance in soybean seedlings.

Journal: Journal of experimental botany20100601

Title: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes.

Journal: Organic letters20100521

Title: Cyanoacetamide MCR (III): three-component Gewald reactions revisited.

Journal: Journal of combinatorial chemistry20100101

Title: Automated saccharification assay for determination of digestibility in plant materials.

Journal: Biotechnology for biofuels20100101

Title: Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines.

Journal: European journal of medicinal chemistry20090901

Title: A simplified green chemistry approaches to synthesis of 2-substituted 1,2,3-triazoles and 4-amino-5-cyanopyrazole derivatives conventional heating versus microwave and ultrasound as ecofriendly energy sources.

Journal: Ultrasonics sonochemistry20090801

Title: Cyanoacetamide multicomponent reaction (I): Parallel synthesis of cyanoacetamides.

Journal: Journal of combinatorial chemistry20090101

Title: A concise approach to a gelsemine core structure using an oxygen to carbon bridge swapping strategy.

Journal: Organic letters20081106

Title: Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety.

Journal: European journal of medicinal chemistry20081001

Title: Synthesis and antimicrobial activity of some new pyrazole, fused pyrazolo[3,4-d]-pyrimidine and pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine derivatives.

Journal: Molecules (Basel, Switzerland)20080729

Title: Spectrofluorimetric determination of oxamniquine in dosage forms and spiked human plasma through derivatization with 1-dimethylaminonaphthalene-5-sulphonyl chloride.

Journal: Journal of fluorescence20080301

Title: Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection.

Journal: Arthritis research & therapy20080101

Title: A one-step fusion of 1,3-thiazine and pyrimidine cycles.

Journal: Organic letters20071011

Title: Chiral salen-aluminum complex as a catalyst for enantioselective alpha-addition of isocyanides to aldehydes: asymmetric synthesis of 2-(1-hydroxyalkyl)-5-aminooxazoles.

Journal: Organic letters20070830

Title: HPLC determination of chondrosine in mouse blood plasma after intravenous or oral dose.

Journal: Biological & pharmaceutical bulletin20070801

Title: Total synthesis of anibamine, a novel natural product as a chemokine receptor CCR5 antagonist.

Journal: Organic letters20070510

Title: The tert-amino effect in heterocyclic chemistry: synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives.

Journal: Beilstein journal of organic chemistry20070101

Title: Substituted 2-methylene-1,3-oxazolidines, -1,3-thiazolidines, -1,3-benzothiazines, -1,3-oxazines, and substituted imidazopyrimidinediones from Cl(CH2)nNCO and Cl(CH2)nNCS and active methylene compounds.

Journal: The Journal of organic chemistry20061222

Title: Synthesis and evaluation of 2,6-piperidinedione derivatives as potentially novel compounds with analgesic and other CNS activities.

Journal: Inflammopharmacology20060301

Title: Improved quality control of [18F]FDG by HPLC with UV detection.

Journal: Nuclear medicine and biology20051101

Title: Separation of keratan-sulfate-derived disaccharides by high-performance liquid chromatography and postcolumn derivatization with 2-cyanoacetamide and fluorimetric detection.

Journal: Analytical biochemistry20050715

Title: Microdetermination of chondroitin sulfate in normal human plasma by fluorophore-assisted carbohydrate electrophoresis (FACE).

Journal: Clinica chimica acta; international journal of clinical chemistry20050601

Title: Synthesis of new iso-C-nucleoside analogues from 2-(methyl 2-O-benzyl-4,6-O-benzylidene-3-deoxy-alpha-D-altropyranosid-3-yl)ethanal.

Journal: Carbohydrate research20050321

Title: Characterization of heparan sulfate from the unossified antler of Cervus elaphus.

Journal: Carbohydrate research20050227

Title: Structural variations of piritrexim, a lipophilic inhibitor of human dihydrofolate reductase: synthesis, antitumor activity and molecular modeling investigations.

Journal: European journal of medicinal chemistry20041201

Title: Separation of capsular polysaccharide-K4- and defructosylated-K4-derived disaccharides by high-performance liquid chromatography and postcolumn derivatization with 2-cyanoacetamide and fluorimetric detection.

Journal: Analytical biochemistry20040715

Title: Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.

Journal: Microbiology (Reading, England)20040401

Title: 2-pyridones from cyanoacetamides and enecarbonyl compounds: application to the synthesis of nothapodytine B.

Journal: The Journal of organic chemistry20020614

Title: Conductivity detection for molecular mass estimation of per-O-sulfonated glycosaminoglycans separated by high-performance size-exclusion chromatography.

Journal: Journal of chromatography. A20020614

Title: In vitro and in vivo anti-Trypanosoma cruzi activity of a novel nitro-derivative.

Journal: Memorias do Instituto Oswaldo Cruz20020601

Title: Pretreatment procedure for the microdetermination of chondroitin sulfate in plasma and urine.

Journal: Analytical biochemistry20020315

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