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1094067-13-6,MFCD18251447
Catalog No.:AA008TKC

1094067-13-6 | SCH-1473759 hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
99%
1 week  
$279.00   $195.00
- +
5mg
99%
1 week  
$470.00   $329.00
- +
10mg
99%
1 week  
$660.00   $462.00
- +
50mg
99%
1 week  
$1,479.00   $1,035.00
- +
100mg
99%
1 week  
$2,241.00   $1,569.00
- +
200mg
99%
1 week  
$3,822.00   $2,675.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TKC
Chemical Name:
SCH-1473759 hydrochloride
CAS Number:
1094067-13-6
Molecular Formula:
C20H27ClN8OS
Molecular Weight:
462.9994
MDL Number:
MFCD18251447
SMILES:
CCN(C(CO)(C)C)Cc1nsc(c1)Nc1nc(C)cn2c1ncc2c1c[nH]nc1.Cl
Properties
Computed Properties
 
Complexity:
569  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Aurora kinase inhibitors based on the imidazo[1,2-a]pyrazine core: fluorine and deuterium incorporation improve oral absorption and exposure.

Journal: Journal of medicinal chemistry 20110113

Title: Yu T, et al. Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-,2-a-Pyrazine Core. ACS Med Chem Lett. 2010 Jun 7;1(5):214-8.

Title: Basso AD, et al. SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors. Cancer Chemother Pharmacol. 2011 Oct;68(4):923-33.

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SDS
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Tags:1094067-13-6 Molecular Formula|1094067-13-6 MDL|1094067-13-6 SMILES|1094067-13-6 SCH-1473759 hydrochloride
Catalog No.: AA008TKC
1094067-13-6,MFCD18251447
1094067-13-6 | SCH-1473759 hydrochloride
Pack Size： 2mg
Purity： 99%
1 week
$279.00 $195.00
Pack Size： 5mg
Purity： 99%
1 week
$470.00 $329.00
Pack Size： 10mg
Purity： 99%
1 week
$660.00 $462.00
Pack Size： 50mg
Purity： 99%
1 week
$1,479.00 $1,035.00
Pack Size： 100mg
Purity： 99%
1 week
$2,241.00 $1,569.00
Pack Size： 200mg
Purity： 99%
1 week
$3,822.00 $2,675.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008TKC
Chemical Name: SCH-1473759 hydrochloride
CAS Number: 1094067-13-6
Molecular Formula: C20H27ClN8OS
Molecular Weight: 462.9994
MDL Number: MFCD18251447
SMILES: CCN(C(CO)(C)C)Cc1nsc(c1)Nc1nc(C)cn2c1ncc2c1c[nH]nc1.Cl
Properties
Complexity: 569  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 31  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Aurora kinase inhibitors based on the imidazo[1,2-a]pyrazine core: fluorine and deuterium incorporation improve oral absorption and exposure.

Journal: Journal of medicinal chemistry20110113

Title: Yu T, et al. Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-,2-a-Pyrazine Core. ACS Med Chem Lett. 2010 Jun 7;1(5):214-8.

Title: Basso AD, et al. SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors. Cancer Chemother Pharmacol. 2011 Oct;68(4):923-33.

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