Title: Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose.
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Title: Transferable potentials for phase equilibria-united atom description of five- and six-membered cyclic alkanes and ethers.
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Title: 1,2-Bis[(3,6,9-trimethyl-3,12-ep-oxy-3,4,5,5a,6,7,8,8a,9,10,12,12a-dodeca-hydro-pyrano[4,3-j][1,2]benzodioxepin-4-yl)-oxy]ethane.
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Title: Anti-inflammatory and immunomodulatory mechanisms of artemisinin on contact hypersensitivity.
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Title: Profiling of volatile impurities in tetramethylenedisulfotetramine (TETS) for synthetic-route determination.
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Title: Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors.
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Title: Pharmacokinetic study of the novel, synthetic trioxane antimalarial compound 97-78 in rats using an LC-MS/MS method for quantification.
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Title: Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.
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Title: Medicinal chemistry perspectives of trioxanes and tetraoxanes.
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Title: Liquid chromatographic tandem mass spectrometric assay for simultaneous quantification of compound 97/78 and its in vivo metabolite 97/63, a novel trioxane antimalarial, in human plasma and its application to a protein binding study.
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Title: An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities.
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Title: A greatly under-appreciated fundamental principle of physical organic chemistry.
Journal: International journal of molecular sciences20110101
Title: Trioxaquines: hybrid molecules for the treatment of malaria.
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Title: Synthesis and antimalarial assessment of a new series of orally active amino-functionalized spiro 1,2,4-trioxanes.
Journal: Journal of medicinal chemistry20101111
Title: A suitable preparation of N-sulfonyl-1,2,3,4-tetrahydroisoquinolines and their ring homologs with a reusable Preyssler heteropolyacid as catalyst.
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Title: Interspecies comparison of the pharmacokinetics and oral bioavailability of 99-357, a potent synthetic trioxane antimalarial compound.
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Title: Purified E255L mutant SERCA1a and purified PfATP6 are sensitive to SERCA-type inhibitors but insensitive to artemisinins.
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Title: Chain branching and termination in the low-temperature combustion of n-alkanes: 2-pentyl radical + O2, isomerization and association of the second O2.
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Title: Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii.
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Title: Formaldehyde in the indoor environment.
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Title: The pharmaceutical death-ride of dihydroartemisinin.
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Title: Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose.
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Title: Different behavior of artemisinin and tetraoxane in the oxidative degradation of phospholipid.
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Title: Liquid chromatographic tandem mass spectrometric assay for quantification of 97/78 and its metabolite 97/63: a promising trioxane antimalarial in monkey plasma.
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Title: Antimalarial peroxide dyads from natural artemisinin and hydroxyalkylated 1,2,4-trioxanes.
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Title: Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.
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Title: Diastereoselective preparation of substituted delta-valerolactones. synthesis of (3R,4S)- and (3R,4R)-simplactones.
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Title: New strategy for the construction of epoxy-bridged tetrahydropyran frameworks from trioxane precursors: application to a concise synthesis of a Riesling acetal.
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Title: Piperidine dispiro-1,2,4-trioxane analogues.
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Title: Accretion reactions of octanal catalyzed by sulfuric acid: product identification, reaction pathways, and atmospheric implications.
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Title: Elucidation of the natural artemisinin decomposition route upon iron interaction: a fine electronic redistribution promotes reactivity.
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Title: 1,2,5,10,11,14-hexaoxadispiro[5.2.5.2]hexadecanes: novel spirofused bis-trioxane peroxides.
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Title: Redetermination of 2,4,6-tricyclo-hexyl-1,3,5-trioxane.
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Title: Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
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Title: Photoinduced oxygen capture on immobilized dienone systems. First solid-phase synthesis of trioxane scaffolds.
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Title: Evaluation of some adamantane-based synthetic trioxanes against Plasmodium knowlesi in rhesus monkeys.
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Title: Conversion of antimalarial drug artemisinin to a new series of tricyclic 1,2,4-trioxanes1.
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Title: Malaria-infected mice are cured by a single dose of novel artemisinin derivatives.
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Title: New adamantane-based spiro 1,2,4-trioxanes orally effective against rodent and simian malaria.
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Title: Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate.
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Title: Quantitative NMR spectroscopy of complex technical mixtures using a virtual reference: chemical equilibria and reaction kinetics of formaldehyde-water-1,3,5-trioxane.
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Title: 8-(1-Naphthalen-2-yl-vinyl)-6,7,10-trioxaspiro (4.5) decane, a new 1,2,4-trioxane effective against rodent and simian malaria.
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Title: Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.
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Title: Conformational pathways of saturated six-membered rings. A static and dynamical density functional study.
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Title: HPLC-UV method for assaying 99/357, a synthetic trioxane antimalarial derivative in rat and rabbit serum.
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Title: Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl)deoxoartemisinin.
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Title: Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds.
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Title: Orally active, water-soluble antimalarial 3-aryltrioxanes: short synthesis and preclinical efficacy testing in rodents.
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Title: Biodegradation of formaldehyde and its derivatives in industrial wastewater with methylotrophic yeast Hansenula polymorpha and with the yeast-bioaugmented activated sludge.
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Title: Quantitative (13)C NMR analysis of lignins with internal standards.
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