Title: IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.
Journal: International immunology20140701
Title: Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.
Journal: Amino acids20131201
Title: Addition of an indoleamine 2,3,-dioxygenase inhibitor to B cell-depletion therapy blocks autoreactive B cell activation and recurrence of arthritis in K/BxN mice.
Journal: Arthritis and rheumatism20120701
Title: Effects of indoleamine 2,3-dioxygenases in carbon tetrachloride-induced hepatitis model of rats.
Journal: Cell biochemistry and function20120601
Title: Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase.
Journal: Cancer science20120501
Title: The role of indoleamine 2, 3 dioxygenase in regulating host immunity to leishmania infection.
Journal: Journal of biomedical science20120101
Title: Modulation of tumor tolerance in primary central nervous system malignancies.
Journal: Clinical & developmental immunology20120101
Title: Targeting multiple-myeloma-induced immune dysfunction to improve immunotherapy outcomes.
Journal: Clinical & developmental immunology20120101
Title: Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases.
Journal: Frontiers in immunology20120101
Title: Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.
Journal: Biochimica et biophysica acta20111201
Title: Novel action of 3,4-DAA ameliorating acute liver allograft injury.
Journal: Cell biochemistry and function20111201
Title: Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.
Journal: Nature medicine20110901
Title: The role of indoleamine 2, 3-dioxygenase in lepromatous leprosy immunosuppression.
Journal: Clinical and experimental immunology20110801
Title: Contribution of dehydroepiandrosterone sulfate and progesterone to in vitro regulation of tolerogenic activity of IFN-α-induced dendritic cells.
Journal: Bulletin of experimental biology and medicine20110601
Title: Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20110501
Title: Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells.
Journal: Medical oncology (Northwood, London, England)20110301
Title: Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).
Journal: PloS one20110101
Title: The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells.
Journal: PloS one20110101
Title: Vascular endothelial expression of indoleamine 2,3-dioxygenase 1 forms a positive gradient towards the feto-maternal interface.
Journal: PloS one20110101
Title: Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences20110101
Title: Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells.
Journal: Haematologica20101201
Title: Mesenchymal stem cells inhibit complement activation by secreting factor H.
Journal: Stem cells and development20101101
Title: Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Journal: Journal of immunology (Baltimore, Md. : 1950)20101015
Title: Inhibitor of indoleamine-2,3-dioxygenase 1-methyl-D-tryptophan can stimulate the growth of immunogenic tumors.
Journal: Bulletin of experimental biology and medicine20101001
Title: Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.
Journal: Amino acids20100701
Title: A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity.
Journal: Experimental biology and medicine (Maywood, N.J.)20100701
Title: Rational design of indoleamine 2,3-dioxygenase inhibitors.
Journal: Journal of medicinal chemistry20100211
Title: The role of indoleamine 2,3-dioxygenase in retinal pigment epithelial cell-mediated immune modulation.
Journal: Ocular immunology and inflammation20100101
Title: Melanoma: a model for testing new agents in combination therapies.
Journal: Journal of translational medicine20100101
Title: Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma.
Journal: Immunobiology20100101
Title: Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans.
Journal: PloS one20100101
Title: Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma.
Journal: Gynecologic oncology20091101
Title: IDO and outcomes in ovarian cancer.
Journal: Gynecologic oncology20091101
Title: Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer.
Journal: Cancer research20090701
Title: Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.
Journal: Molecular psychiatry20090501
Title: Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression.
Journal: Human immunology20090501
Title: Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques.
Journal: Journal of immunology (Baltimore, Md. : 1950)20090401
Title: Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.
Journal: The international journal of biochemistry & cell biology20090301
Title: Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes.
Journal: BMC cancer20090101
Title: Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20081115
Title: The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation.
Journal: Journal of immunology (Baltimore, Md. : 1950)20081015
Title: Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy.
Journal: The Biochemical journal20080915
Title: Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury.
Journal: American journal of physiology. Renal physiology20080701
Title: Antimicrobial and immunoregulatory effects mediated by human lung cells: role of IFN-gamma-induced tryptophan degradation.
Journal: FEMS immunology and medical microbiology20080301
Title: Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells.
Journal: Blood20080215
Title: Increased striatal serotonin synthesis following cortical resection in children with intractable epilepsy.
Journal: Epilepsy research20080201
Title: Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20080101
Title: Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction.
Journal: Clinical immunology (Orlando, Fla.)20080101
Title: HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation.
Journal: PloS one20080101
Title: Effect of Kidney-replenishing herb on the indoleamine 2,3-dioxygenase of human syncytiotrophoblasts cultured in vitro and the balance of helper T-cell cytokines.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology20071101
Title: Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats.
Journal: Transplantation20071027
Title: Proapoptotic activity of indoleamine 2,3-dioxygenase expressed in renal tubular epithelial cells.
Journal: American journal of physiology. Renal physiology20070901
Title: Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.
Journal: Cancer research20070801
Title: Indoleamine 2, 3-dioxygenase expression in cells of human acute monocyte leukemia (M(5)) and acute lymphocyte leukemia and therapeutic effect of its inhibitor 1-methyl tryptophan.
Journal: Zhongguo shi yan xue ye xue za zhi20070601
Title: Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition.
Journal: Journal of immunology (Baltimore, Md. : 1950)20061201
Title: Indoleamine 2,3-dioxygenase participates in the interferon-gamma-induced cell death process in cultured bovine luteal cells.
Journal: Biology of reproduction20060301
Title: Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
Journal: Blood20051001
Title: Temperature-sensitive polymer-conjugated IFN-gamma induces the expression of IDO mRNA and activity by fibroblasts populated in collagen gel (FPCG).
Journal: Journal of cellular physiology20041001
Title: Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.
Journal: The Journal of clinical investigation20040715
Title: Hou DY, et al. Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophancorrelates with antitumor responses. Cancer Res. 2007 Jan 15;67(2):792-801.
Title: Metz R, et al. IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan. Oncoimmunology. 2012;1(9):1460-1468.
