119477-85-9,MFCD00270915
Catalog No.:AA000ISD

119477-85-9 | 1,5-Hexanediol, 6-[6-[(1E,3R,5Z)-3-hydroxy-1,5-undecadien-1-yl]-2-pyridinyl]-, (5S)-

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Purity
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1mg
≥95%
in stock  
$1,363.00   $954.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000ISD
Chemical Name:
1,5-Hexanediol, 6-[6-[(1E,3R,5Z)-3-hydroxy-1,5-undecadien-1-yl]-2-pyridinyl]-, (5S)-
CAS Number:
119477-85-9
Molecular Formula:
C22H35NO3
Molecular Weight:
361.5182
MDL Number:
MFCD00270915
SMILES:
CCCCC/C=C\C[C@H](/C=C/c1cccc(n1)C[C@H](CCCCO)O)O
Properties
Computed Properties
 
Complexity:
384  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
2  
Formal Charge:
0  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
14  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.1  

Literature

Title: Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120201

Title: Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain.

Journal: Glia 20100401

Title: 4-Hydroxynonenal enhances MMP-9 production in murine macrophages via 5-lipoxygenase-mediated activation of ERK and p38 MAPK.

Journal: Toxicology and applied pharmacology 20100115

Title: Leukotriene B4, administered via intracerebroventricular injection, attenuates the antigen-induced asthmatic response in sensitized guinea pigs.

Journal: Journal of neuroinflammation 20100101

Title: Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats.

Journal: Respiratory research 20100101

Title: Relationship between calcium release and NADPH oxidase inhibition in human neutrophils.

Journal: Biochemical and biophysical research communications 20090619

Title: 15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090601

Title: Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice.

Journal: British journal of pharmacology 20080701

Title: Endothelium-dependent vascular responses induced by leukotriene B4.

Journal: Prostaglandins & other lipid mediators 20070501

Title: Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070315

Title: Homologous desensitisation of the mouse leukotriene B4 receptor involves protein kinase C-mediated phosphorylation of serine 127.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

Title: Leukotrienes modulate cytokine release from dendritic cells.

Journal: Immunology 20051201

Title: Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention.

Journal: Carcinogenesis 20050401

Title: Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2.

Journal: European journal of pharmacology 20040919

Title: Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.

Journal: British journal of pharmacology 20030801

Title: Modulation of leukotriene B4 receptor-1 expression by dexamethasone: potential mechanism for enhanced neutrophil survival.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020401

Title: A novel hepatointestinal leukotriene B4 receptor. Cloning and functional characterization.

Journal: The Journal of biological chemistry 20001229

Title: Characterization of the cloned guinea pig leukotriene B4 receptor: comparison to its human orthologue.

Journal: European journal of pharmacology 19990910

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Related Products of 119477-85-9
Tags:119477-85-9 Molecular Formula|119477-85-9 MDL|119477-85-9 SMILES|119477-85-9 1,5-Hexanediol, 6-[6-[(1E,3R,5Z)-3-hydroxy-1,5-undecadien-1-yl]-2-pyridinyl]-, (5S)-
Catalog No.: AA000ISD
119477-85-9,MFCD00270915
119477-85-9 | 1,5-Hexanediol, 6-[6-[(1E,3R,5Z)-3-hydroxy-1,5-undecadien-1-yl]-2-pyridinyl]-, (5S)-
Pack Size: 1mg
Purity: ≥95%
in stock
$1,363.00 $954.00
Quantity
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bulk Quotation Request
Technical Information
Catalog Number: AA000ISD
Chemical Name: 1,5-Hexanediol, 6-[6-[(1E,3R,5Z)-3-hydroxy-1,5-undecadien-1-yl]-2-pyridinyl]-, (5S)-
CAS Number: 119477-85-9
Molecular Formula: C22H35NO3
Molecular Weight: 361.5182
MDL Number: MFCD00270915
SMILES: CCCCC/C=C\C[C@H](/C=C/c1cccc(n1)C[C@H](CCCCO)O)O
Properties
Complexity: 384  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 2  
Formal Charge: 0  
Heavy Atom Count: 26  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 14  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.1  
Literature fold

Title: Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20120201

Title: Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain.

Journal: Glia20100401

Title: 4-Hydroxynonenal enhances MMP-9 production in murine macrophages via 5-lipoxygenase-mediated activation of ERK and p38 MAPK.

Journal: Toxicology and applied pharmacology20100115

Title: Leukotriene B4, administered via intracerebroventricular injection, attenuates the antigen-induced asthmatic response in sensitized guinea pigs.

Journal: Journal of neuroinflammation20100101

Title: Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats.

Journal: Respiratory research20100101

Title: Relationship between calcium release and NADPH oxidase inhibition in human neutrophils.

Journal: Biochemical and biophysical research communications20090619

Title: 15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20090601

Title: Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice.

Journal: British journal of pharmacology20080701

Title: Endothelium-dependent vascular responses induced by leukotriene B4.

Journal: Prostaglandins & other lipid mediators20070501

Title: Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20070315

Title: Homologous desensitisation of the mouse leukotriene B4 receptor involves protein kinase C-mediated phosphorylation of serine 127.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20070101

Title: Leukotrienes modulate cytokine release from dendritic cells.

Journal: Immunology20051201

Title: Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention.

Journal: Carcinogenesis20050401

Title: Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2.

Journal: European journal of pharmacology20040919

Title: Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.

Journal: British journal of pharmacology20030801

Title: Modulation of leukotriene B4 receptor-1 expression by dexamethasone: potential mechanism for enhanced neutrophil survival.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020401

Title: A novel hepatointestinal leukotriene B4 receptor. Cloning and functional characterization.

Journal: The Journal of biological chemistry20001229

Title: Characterization of the cloned guinea pig leukotriene B4 receptor: comparison to its human orthologue.

Journal: European journal of pharmacology19990910

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