Title: Antiseptic effects of dabrafenib on TGFBIp-induced septic responses.
Journal: Chemico-biological interactions 20171225
Title: Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption.
Journal: Chemico-biological interactions 20160825
Title: Optimising the combination dosing strategy of abemaciclib and vemurafenib in BRAF-mutated melanoma xenograft tumours.
Journal: British journal of cancer 20160315
Title: Paradoxical activation of MEK/ERK signaling induced by B-Raf inhibition enhances DR5 expression and DR5 activation-induced apoptosis in Ras-mutant cancer cells.
Journal: Scientific reports 20160101
Title: Clinical development of dabrafenib in BRAF mutant melanoma and other malignancies.
Journal: Expert opinion on drug metabolism & toxicology 20130701
Title: BRAF inhibitor activity in V600R metastatic melanoma.
Journal: European journal of cancer (Oxford, England : 1990) 20130301
Title: BRAF inhibition and beyond in advanced melanoma.
Journal: Lancet (London, England) 20120728
Title: Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial.
Journal: Lancet (London, England) 20120728
Title: Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management.
Journal: Archives of dermatology 20120301
Title: Small molecule inhibitors of BRAF in clinical trials.
Journal: Bioorganic & medicinal chemistry letters 20120115
Title: Overcoming metastatic melanoma with BRAF inhibitors.
Journal: Archives of pharmacal research 20110501
Title: Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Journal: Nature 20100930
Title: Greger JG, et al. Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations. Mol Cancer Ther, 2012, 11(4), 909-920.
Title: Lee S, et al. Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption. Chem Biol Interact. 2016 Jul 22.
Title: Jung B, et al. Anti-septic effects of dabrafenib on HMGB1-mediated inflammatory responses. BMB Rep. 2016 Apr;49(4):214-9.
Title: Alexander M Menzies, et al. Dabrafenib and its potential for the treatment of metastatic melanoma. Drug Des Devel Ther. 2012; 6: 391–405.
Title: Posobiec LM, et al. Early Vaginal Opening in Juvenile Female Rats Given BRAF-Inhibitor Dabrafenib Is Not Associated with Early Physiologic Sexual Maturation. Birth Defects Res B Dev Reprod Toxicol. 2015 Dec;104(6):244-52.