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1201438-56-3,MFCD15144635
Catalog No.:AA000QBA

1201438-56-3 | Duvelisib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$22.00   $16.00
- +
25mg
98%
in stock  
$243.00   $170.00
- +
50mg
≥98%
in stock  
$425.00   $298.00
- +
100mg
95%
in stock  
$470.00   $329.00
- +
250mg
95%
in stock  
$887.00   $621.00
- +
1g
98%
in stock  
$2,013.00   $1,409.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000QBA
Chemical Name:
Duvelisib
CAS Number:
1201438-56-3
Molecular Formula:
C22H17ClN6O
Molecular Weight:
416.8630
MDL Number:
MFCD15144635
SMILES:
Clc1cccc2c1c(=O)n(c(c2)[C@@H](Nc1ncnc2c1nc[nH]2)C)c1ccccc1
Properties
Computed Properties
 
Complexity:
668  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.1  

Literature

Title: Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance.

Journal: Journal of molecular biology 20170217

Title: PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.

Journal: Chemistry & biology 20131121

Title: Pillinger G, et al. Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection. Oncotarget. 2016 Jun 28;7(26):39784-39795.

Title: G?ckeritz E, et al. Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells. Int J Cancer. 2015 Nov 1;137(9):2234-42.

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SDS
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Tags:1201438-56-3 Molecular Formula|1201438-56-3 MDL|1201438-56-3 SMILES|1201438-56-3 Duvelisib
Catalog No.: AA000QBA
1201438-56-3,MFCD15144635
1201438-56-3 | Duvelisib
Pack Size： 1mg
Purity： 98%
in stock
$22.00 $16.00
Pack Size： 25mg
Purity： 98%
in stock
$243.00 $170.00
Pack Size： 50mg
Purity： ≥98%
in stock
$425.00 $298.00
Pack Size： 100mg
Purity： 95%
in stock
$470.00 $329.00
Pack Size： 250mg
Purity： 95%
in stock
$887.00 $621.00
Pack Size： 1g
Purity： 98%
in stock
$2,013.00 $1,409.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA000QBA
Chemical Name: Duvelisib
CAS Number: 1201438-56-3
Molecular Formula: C22H17ClN6O
Molecular Weight: 416.8630
MDL Number: MFCD15144635
SMILES: Clc1cccc2c1c(=O)n(c(c2)[C@@H](Nc1ncnc2c1nc[nH]2)C)c1ccccc1
Properties
Complexity: 668  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 30  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.1  
Literature fold

Title: Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance.

Journal: Journal of molecular biology20170217

Title: PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.

Journal: Chemistry & biology20131121

Title: Pillinger G, et al. Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection. Oncotarget. 2016 Jun 28;7(26):39784-39795.

Title: G?ckeritz E, et al. Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells. Int J Cancer. 2015 Nov 1;137(9):2234-42.

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