123690-79-9,MFCD00882736
Catalog No.:AA000KVM

123690-79-9 | Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥95%
in stock  
$238.00   $166.00
- +
50mg
≥95%
in stock  
$1,056.00   $739.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000KVM
Chemical Name:
Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
CAS Number:
123690-79-9
Molecular Formula:
C8H20NO4P
Molecular Weight:
225.2225
MDL Number:
MFCD00882736
SMILES:
NCCCP(=O)(C(OCC)OCC)O
Properties
Computed Properties
 
Complexity:
182  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-3.3  

Literature

Title: Reversal of inhibition of putative dopaminergic neurons of the ventral tegmental area: interaction of GABA(B) and D2 receptors.

Journal: Neuroscience 20121213

Title: The role of GABAergic signalling in stress-induced suppression of gonadotrophin-releasing hormone pulse generator frequency in female rats.

Journal: Journal of neuroendocrinology 20120301

Title: Effects of the GABAB receptor agonist baclofen on primary drinking in rats.

Journal: European journal of pharmacology 20120115

Title: GABAB receptor-positive modulators: brain region-dependent effects.

Journal: The Journal of pharmacology and experimental therapeutics 20120101

Title: Activation of presynaptic GABAB receptors modulates GABAergic and glutamatergic inputs to the medial geniculate body.

Journal: Hearing research 20111001

Title: Pyramidal neurons are 'neurogenic hubs' in the neurovascular coupling response to whisker stimulation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110706

Title: GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 20101001

Title: Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit.

Journal: Brain research 20100716

Title: Both GABAA and GABAB receptors mediate vagal inhibition in nucleus tractus solitarii neurones in anaesthetized rats.

Journal: Autonomic neuroscience : basic & clinical 20100115

Title: Pain relief by spinal cord stimulation involves serotonergic mechanisms: an experimental study in a rat model of mononeuropathy.

Journal: Pain 20091215

Title: Short-term synaptic plasticity at the main and vomeronasal olfactory receptor to mitral cell synapse in frog.

Journal: The European journal of neuroscience 20091203

Title: Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348).

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: Pharmacological and autoradiographic studies on the pathophysiological role of GABA(B) receptors in the dystonic hamster: pronounced antidystonic effects of baclofen after striatal injections.

Journal: Neuroscience 20090818

Title: Infantile spasms and Down syndrome: a new animal model.

Journal: Pediatric research 20090501

Title: The physiological role of pre- and postsynaptic GABA(B) receptors in membrane excitability and synaptic transmission of neurons in the rat's dorsal cortex of the inferior colliculus.

Journal: Neuroscience 20090421

Title: Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus.

Journal: Epilepsy research 20090401

Title: GABA(B) presynaptic receptors modulate glycine exocytosis from mouse spinal cord and hippocampus glycinergic nerve endings.

Journal: Pharmacological research 20090301

Title: GABA transporter GAT1 prevents spillover at proximal and distal GABA synapses onto primate prefrontal cortex neurons.

Journal: Journal of neurophysiology 20090201

Title: Interaction between GABA and norepinephrine in interleukin-1beta-induced suppression of the luteinizing hormone surge.

Journal: Brain research 20090112

Title: Attenuation of morphine withdrawal signs by a GABAB receptor agonist in the locus coeruleus of rats.

Journal: Behavioural brain research 20090103

Title: GABAB receptors within the ventral tegmental area are involved in the expression and acquisition of morphine-induced place preference in morphine-sensitized rats.

Journal: Pharmacology, biochemistry, and behavior 20090101

Title: SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons.

Journal: The European journal of neuroscience 20080901

Title: Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem.

Journal: Neuron 20080710

Title: Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080701

Title: Differentiating the discriminative stimulus effects of gamma-hydroxybutyrate and ethanol in a three-choice drug discrimination procedure in rats.

Journal: Pharmacology, biochemistry, and behavior 20080601

Title: Regulation of cardiac sympathetic afferent reflex by GABA(A) and GABA(B) receptors in paraventricular nucleus in rats.

Journal: The European journal of neuroscience 20080601

Title: Attenuation of morphine withdrawal signs by muscimol in the locus coeruleus of rats.

Journal: Behavioural pharmacology 20080501

Title: Comparative pharmacological activity of optical isomers of phenibut.

Journal: European journal of pharmacology 20080331

Title: Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone.

Journal: Journal of pharmacological sciences 20080201

Title: Effect of GABAergic substances on firing rate and thermal coefficient of hypothalamic neurons in the juvenile chicken.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071001

Title: Understanding your inhibitions: modulation of brain cortical metabolism by GABA(B) receptors.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070801

Title: GABAergic mechanisms of the lateral parabrachial nucleus on sodium appetite.

Journal: Brain research bulletin 20070712

Title: Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.

Journal: Psychopharmacology 20070601

Title: Effect of GABAergic ligands on the anxiolytic-like activity of DOI (a 5-HT(2A/2C) agonist) in the four-plate test in mice.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070101

Title: GABAB receptor blockade enhances theta and gamma rhythms in the hippocampus of behaving rats.

Journal: Hippocampus 20070101

Title: RVLM glycine receptors mediate GABAA and GABAB)independent sympathoinhibition from CVLM in rats.

Journal: Brain research 20061213

Title: Nucleus-specific abnormalities of GABAergic synaptic transmission in a genetic model of absence seizures.

Journal: Journal of neurophysiology 20061201

Title: GABA-mediated neurotransmission in the nucleus of the solitary tract alters resting ventilation following exposure to chronic hypoxia in conscious rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20061101

Title: Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.

Journal: Brain research 20061018

Title: A spatially structured network of inhibitory and excitatory connections directs impulse traffic within the lateral amygdala.

Journal: Neuroscience 20060901

Title: On the mechanism of carbamazepine-induced antinociception in the formalin test.

Journal: The International journal of neuroscience 20060901

Title: Effect of GABA receptor agonists or antagonists on morphine-induced Straub tail in mice.

Journal: The International journal of neuroscience 20060801

Title: GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures.

Journal: European journal of pharmacology 20060710

Title: Detection of gamma-aminobutyric acid-induced glutamate release in acute mouse hippocampal slices with a patch sensor.

Journal: Analytical biochemistry 20060601

Title: Discriminative stimulus effects of GHB and GABA(B) agonists are differentially attenuated by CGP35348.

Journal: European journal of pharmacology 20060524

Title: Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone.

Journal: Behavioural pharmacology 20060501

Title: Discriminative stimulus effects of gamma-hydroxybutyrate: role of training dose.

Journal: The Journal of pharmacology and experimental therapeutics 20060401

Title: Disinhibition of spinal responses to primary afferent input by antagonism at GABA receptors in urethane-anaesthetised rats is dependent on NMDA and metabotropic glutamate receptors.

Journal: Neuropharmacology 20060401

Title: Dopamine-mediated actions of ephedrine in the rat substantia nigra.

Journal: Brain research 20060119

Title: Effect of a selective GABA(B) receptor agonist baclofen on the mu-opioid receptor agonist-induced antinociceptive, emetic and rewarding effects.

Journal: Neuropharmacology 20051201

Title: Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome.

Journal: Epilepsia 20051201

Title: Different effects of GABAergic receptors located in the ventral tegmental area on the expression of morphine-induced conditioned place preference in rat.

Journal: European journal of pharmacology 20051107

Title: Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro.

Journal: Brain research bulletin 20051030

Title: Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) in rats discriminating GHB from baclofen and diazepam.

Journal: The Journal of pharmacology and experimental therapeutics 20050701

Title: Gamma aminobutyric acid regulates glucosensitive neuropeptide Y neurons in arcuate nucleus via A/B receptors.

Journal: Neuroreport 20050621

Title: Novel gamma-hydroxybutyric acid (GHB) analogs share some, but not all, of the behavioral effects of GHB and GABAB receptor agonists.

Journal: The Journal of pharmacology and experimental therapeutics 20050601

Title: Evidence for a selective prefrontal cortical GABA(B) receptor-mediated inhibition of glutamate release in the ventral tegmental area: a dual probe microdialysis study in the awake rat.

Journal: Neuroscience 20050101

Title: Mechanisms underlying the sympathomimetic cardiovascular responses elicited by gamma-hydroxybutyrate.

Journal: Journal of cardiovascular pharmacology 20041201

Title: Pentobarbital induces thalamic oscillations in brain slices, modulated by GABA and glycine receptors.

Journal: Neuropharmacology 20041201

Title: The effects of intraperitoneal and intracerebroventricular administration of the GABAB receptor antagonist CGP 35348 on food intake in rats.

Journal: European journal of pharmacology 20041025

Title: Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats.

Journal: Brain research bulletin 20040930

Title: Evidence for a differential medial prefrontal dopamine D1 and D2 receptor regulation of local and ventral tegmental glutamate and GABA release: a dual probe microdialysis study in the awake rat.

Journal: Brain research 20040813

Title: Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons.

Journal: Neuron 20040624

Title: Nigral GABAergic inhibition upon mesencephalic dopaminergic cell groups in rats.

Journal: The European journal of neuroscience 20040501

Title: Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Mechanisms and significance of reduced activity and responsiveness in resting frog tadpoles.

Journal: The Journal of experimental biology 20040301

Title: Isoflurane facilitates hiccup-like reflex through gamma aminobutyric acid (GABA)A- and suppresses through GABAB-receptors in pentobarbital-anesthetized cats.

Journal: Anesthesia and analgesia 20040201

Title: Effects of gamma-hydroxybutyrate (GHB) on schedule-controlled responding in rats: role of GHB and GABAB receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20040101

Title: GABA(B) receptor activation and limbic network ictogenesis.

Journal: Neuropharmacology 20040101

Title: Does gabapentin act as an agonist at native GABA(B) receptors?

Journal: Journal of biomedical science 20040101

Title: Contribution of GABA(B) receptor-mediated inhibition to the expression and termination of group I mGluR-induced ictaform bursts.

Journal: Epilepsy research 20040101

Title: Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation.

Journal: The European journal of neuroscience 20031201

Title: Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.

Journal: Journal of neurochemistry 20031101

Title: Inhibitory effects of spinal baclofen on spinal dorsal horn neurones in inflamed and neuropathic rats in vivo.

Journal: Brain research 20031010

Title: Baclofen inhibits guinea pig magnocellular neurones via activation of an inwardly rectifying K+ conductance.

Journal: The Journal of physiology 20030815

Title: Treatment of spontaneous and chemically induced EEG paroxysms in the Fischer-344 rat with traditional antiepileptic drugs or AED+CGP 35348 polytherapy.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20030801

Title: Hindquarters vasoconstriction through central GABA(B) receptors in conscious rats.

Journal: Experimental physiology 20030701

Title: The anaesthetic agent propofol interacts with GABA(B)-receptors: an electrophysiological study in rat.

Journal: Life sciences 20030502

Title: Identified sources and targets of slow inhibition in the neocortex.

Journal: Science (New York, N.Y.) 20030321

Title: The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic system.

Journal: Neuroscience 20030101

Title: Action of GABA-B antagonist on cortical epileptic afterdischarges in rats is similar to that of GABA-A antagonist.

Journal: Physiological research 20030101

Title: Modulation of the components of the rat dark-adapted electroretinogram by the three subtypes of GABA receptors.

Journal: Visual neuroscience 20030101

Title: Epileptiform synchronization and GABA(B) receptor antagonism in the juvenile rat hippocampus.

Journal: The Journal of pharmacology and experimental therapeutics 20021201

Title: Effects of intrahippocampal injection of GABAergic drugs on memory retention of passive avoidance learning in rats.

Journal: Journal of psychopharmacology (Oxford, England) 20021201

Title: Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists.

Journal: Neuropharmacology 20020901

Title: Gamma-aminobutyric acid circuits shape response properties of auditory cortex neurons.

Journal: Brain research 20020719

Title: Synchronized oscillations caused by disinhibition in rodent neocortex are generated by recurrent synaptic activity mediated by AMPA receptors.

Journal: The Journal of physiology 20020715

Title: Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria).

Journal: The Journal of pharmacology and experimental therapeutics 20020701

Title: International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function.

Journal: Pharmacological reviews 20020601

Title: Long-term potentiation alters the modulator pharmacology of AMPA-type glutamate receptors.

Journal: Journal of neurophysiology 20020601

Title: GABA-B-related activity in processing of transcallosal response in cat motor cortex.

Journal: Journal of neuroscience research 20020515

Title: The effects of fruit essential oil of the Pimpinella anisum on acquisition and expression of morphine induced conditioned place preference in mice.

Journal: Journal of ethnopharmacology 20020401

Title: GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020301

Title: Effect of intracerebroventricular injection of GABA receptor agents on morphine-induced antinociception in the formalin test.

Journal: Journal of psychopharmacology (Oxford, England) 20020301

Title: Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011101

Title: Spinal GABA(B)-receptor antagonism increases nociceptive transmission in vivo.

Journal: Neuroreport 20011029

Title: Evidence for a role for GABA(A) and NMDA receptors in ethanol inhibition of long-term potentiation.

Journal: Brain research. Molecular brain research 20011019

Title: Opioid and GABA receptors involved in mediation and modulation of tonic and stimulus-evoked inhibition of a spinal reflex in the decerebrated and spinalized rabbit.

Journal: Neuropharmacology 20010901

Title: Network and intrinsic contributions to carbachol-induced oscillations in the rat subiculum.

Journal: Journal of neurophysiology 20010901

Title: GABA(B) and NMDA receptors contribute to spindle-like oscillations in rat thalamus in vitro.

Journal: Journal of neurophysiology 20010901

Title: gamma-Hydroxybutyrate modulation of glutamate levels in the hippocampus: an in vivo and in vitro study.

Journal: Journal of neurochemistry 20010901

Title: GABA mechanisms and antinociception in mice with ligated sciatic nerve.

Journal: Pharmacology & toxicology 20010801

Title: Developmental characteristics of epileptiform activity in immature rat neocortex: a comparison of four in vitro seizure models.

Journal: Brain research. Developmental brain research 20010629

Title: GABA(A)-dependent chloride influx modulates reversal potential of GABA(B)-mediated IPSPs in hippocampal pyramidal cells.

Journal: Journal of neurophysiology 20010601

Title: Heterogeneous susceptibility of GABA(A) receptor-mediated IPSCs to depolarization-induced suppression of inhibition in rat hippocampus.

Journal: The Journal of physiology 20010501

Title: Gamma-vinyl GABA reduces paired pulse inhibition in the rat dentate gyrus in vivo and in vitro.

Journal: Epilepsy research 20010501

Title: Short-term plasticity at inhibitory synapses in rat striatum and its effects on striatal output.

Journal: Journal of neurophysiology 20010501

Title: Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons.

Journal: Neuroreport 20010212

Title: Multireceptor GABAergic regulation of synaptic communication in amphibian retina.

Journal: The Journal of physiology 20010101

Title: GABA(A) but not GABA(B) receptor stimulation induces antianxiety profile in rats.

Journal: Pharmacology, biochemistry, and behavior 20010101

Title: The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.

Journal: British journal of pharmacology 20001101

Title: Inhibition of catechol-O-methyltransferase (COMT) in the brain does not affect the action of dopamine and levodopa: an in vitro electrophysiological evidence from rat mesencephalic dopamine neurons.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 19990101

Title: Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

Journal: Nature 19970320

Title: CGP 35348 and CGP 55845A block the baclofen-induced depression of dorsal root evoked potentials in lumbar motoneurons of the neonatal rat.

Journal: Neuroscience letters 19960823

Title: Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.

Journal: The Journal of pharmacology and experimental therapeutics 19950901

Title: Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.

Journal: Journal of medicinal chemistry 19950818

Title: Antagonism of baclofen-induced depression of whole-cell synaptic currents in spinal dorsal horn neurones by the potent GABAB antagonist CGP55845.

Journal: Neuropharmacology 19931201

Title: Reversal of scopolamine-induced amnesia by the GABAB receptor antagonist CGP 35348 in the mouse.

Journal: Brain research. Cognitive brain research 19930401

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Tags:123690-79-9 Molecular Formula|123690-79-9 MDL|123690-79-9 SMILES|123690-79-9 Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
Catalog No.: AA000KVM
123690-79-9,MFCD00882736
123690-79-9 | Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
Pack Size: 10mg
Purity: ≥95%
in stock
$238.00 $166.00
Pack Size: 50mg
Purity: ≥95%
in stock
$1,056.00 $739.00
Quantity
- +
Add to Card
Order Now
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Technical Information
Catalog Number: AA000KVM
Chemical Name: Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
CAS Number: 123690-79-9
Molecular Formula: C8H20NO4P
Molecular Weight: 225.2225
MDL Number: MFCD00882736
SMILES: NCCCP(=O)(C(OCC)OCC)O
Properties
Complexity: 182  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 14  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -3.3  
Literature fold

Title: Reversal of inhibition of putative dopaminergic neurons of the ventral tegmental area: interaction of GABA(B) and D2 receptors.

Journal: Neuroscience20121213

Title: The role of GABAergic signalling in stress-induced suppression of gonadotrophin-releasing hormone pulse generator frequency in female rats.

Journal: Journal of neuroendocrinology20120301

Title: Effects of the GABAB receptor agonist baclofen on primary drinking in rats.

Journal: European journal of pharmacology20120115

Title: GABAB receptor-positive modulators: brain region-dependent effects.

Journal: The Journal of pharmacology and experimental therapeutics20120101

Title: Activation of presynaptic GABAB receptors modulates GABAergic and glutamatergic inputs to the medial geniculate body.

Journal: Hearing research20111001

Title: Pyramidal neurons are 'neurogenic hubs' in the neurovascular coupling response to whisker stimulation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20110706

Title: GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.

Journal: The Journal of pharmacology and experimental therapeutics20101001

Title: Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit.

Journal: Brain research20100716

Title: Both GABAA and GABAB receptors mediate vagal inhibition in nucleus tractus solitarii neurones in anaesthetized rats.

Journal: Autonomic neuroscience : basic & clinical20100115

Title: Pain relief by spinal cord stimulation involves serotonergic mechanisms: an experimental study in a rat model of mononeuropathy.

Journal: Pain20091215

Title: Short-term synaptic plasticity at the main and vomeronasal olfactory receptor to mitral cell synapse in frog.

Journal: The European journal of neuroscience20091203

Title: Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.

Journal: American journal of physiology. Heart and circulatory physiology20091101

Title: Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348).

Journal: The Journal of pharmacology and experimental therapeutics20090901

Title: Pharmacological and autoradiographic studies on the pathophysiological role of GABA(B) receptors in the dystonic hamster: pronounced antidystonic effects of baclofen after striatal injections.

Journal: Neuroscience20090818

Title: Infantile spasms and Down syndrome: a new animal model.

Journal: Pediatric research20090501

Title: The physiological role of pre- and postsynaptic GABA(B) receptors in membrane excitability and synaptic transmission of neurons in the rat's dorsal cortex of the inferior colliculus.

Journal: Neuroscience20090421

Title: Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus.

Journal: Epilepsy research20090401

Title: GABA(B) presynaptic receptors modulate glycine exocytosis from mouse spinal cord and hippocampus glycinergic nerve endings.

Journal: Pharmacological research20090301

Title: GABA transporter GAT1 prevents spillover at proximal and distal GABA synapses onto primate prefrontal cortex neurons.

Journal: Journal of neurophysiology20090201

Title: Interaction between GABA and norepinephrine in interleukin-1beta-induced suppression of the luteinizing hormone surge.

Journal: Brain research20090112

Title: Attenuation of morphine withdrawal signs by a GABAB receptor agonist in the locus coeruleus of rats.

Journal: Behavioural brain research20090103

Title: GABAB receptors within the ventral tegmental area are involved in the expression and acquisition of morphine-induced place preference in morphine-sensitized rats.

Journal: Pharmacology, biochemistry, and behavior20090101

Title: SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons.

Journal: The European journal of neuroscience20080901

Title: Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem.

Journal: Neuron20080710

Title: Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20080701

Title: Differentiating the discriminative stimulus effects of gamma-hydroxybutyrate and ethanol in a three-choice drug discrimination procedure in rats.

Journal: Pharmacology, biochemistry, and behavior20080601

Title: Regulation of cardiac sympathetic afferent reflex by GABA(A) and GABA(B) receptors in paraventricular nucleus in rats.

Journal: The European journal of neuroscience20080601

Title: Attenuation of morphine withdrawal signs by muscimol in the locus coeruleus of rats.

Journal: Behavioural pharmacology20080501

Title: Comparative pharmacological activity of optical isomers of phenibut.

Journal: European journal of pharmacology20080331

Title: Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone.

Journal: Journal of pharmacological sciences20080201

Title: Effect of GABAergic substances on firing rate and thermal coefficient of hypothalamic neurons in the juvenile chicken.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology20071001

Title: Understanding your inhibitions: modulation of brain cortical metabolism by GABA(B) receptors.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism20070801

Title: GABAergic mechanisms of the lateral parabrachial nucleus on sodium appetite.

Journal: Brain research bulletin20070712

Title: Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.

Journal: Psychopharmacology20070601

Title: Effect of GABAergic ligands on the anxiolytic-like activity of DOI (a 5-HT(2A/2C) agonist) in the four-plate test in mice.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20070101

Title: GABAB receptor blockade enhances theta and gamma rhythms in the hippocampus of behaving rats.

Journal: Hippocampus20070101

Title: RVLM glycine receptors mediate GABAA and GABAB)independent sympathoinhibition from CVLM in rats.

Journal: Brain research20061213

Title: Nucleus-specific abnormalities of GABAergic synaptic transmission in a genetic model of absence seizures.

Journal: Journal of neurophysiology20061201

Title: GABA-mediated neurotransmission in the nucleus of the solitary tract alters resting ventilation following exposure to chronic hypoxia in conscious rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20061101

Title: Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.

Journal: Brain research20061018

Title: A spatially structured network of inhibitory and excitatory connections directs impulse traffic within the lateral amygdala.

Journal: Neuroscience20060901

Title: On the mechanism of carbamazepine-induced antinociception in the formalin test.

Journal: The International journal of neuroscience20060901

Title: Effect of GABA receptor agonists or antagonists on morphine-induced Straub tail in mice.

Journal: The International journal of neuroscience20060801

Title: GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures.

Journal: European journal of pharmacology20060710

Title: Detection of gamma-aminobutyric acid-induced glutamate release in acute mouse hippocampal slices with a patch sensor.

Journal: Analytical biochemistry20060601

Title: Discriminative stimulus effects of GHB and GABA(B) agonists are differentially attenuated by CGP35348.

Journal: European journal of pharmacology20060524

Title: Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone.

Journal: Behavioural pharmacology20060501

Title: Discriminative stimulus effects of gamma-hydroxybutyrate: role of training dose.

Journal: The Journal of pharmacology and experimental therapeutics20060401

Title: Disinhibition of spinal responses to primary afferent input by antagonism at GABA receptors in urethane-anaesthetised rats is dependent on NMDA and metabotropic glutamate receptors.

Journal: Neuropharmacology20060401

Title: Dopamine-mediated actions of ephedrine in the rat substantia nigra.

Journal: Brain research20060119

Title: Effect of a selective GABA(B) receptor agonist baclofen on the mu-opioid receptor agonist-induced antinociceptive, emetic and rewarding effects.

Journal: Neuropharmacology20051201

Title: Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome.

Journal: Epilepsia20051201

Title: Different effects of GABAergic receptors located in the ventral tegmental area on the expression of morphine-induced conditioned place preference in rat.

Journal: European journal of pharmacology20051107

Title: Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro.

Journal: Brain research bulletin20051030

Title: Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) in rats discriminating GHB from baclofen and diazepam.

Journal: The Journal of pharmacology and experimental therapeutics20050701

Title: Gamma aminobutyric acid regulates glucosensitive neuropeptide Y neurons in arcuate nucleus via A/B receptors.

Journal: Neuroreport20050621

Title: Novel gamma-hydroxybutyric acid (GHB) analogs share some, but not all, of the behavioral effects of GHB and GABAB receptor agonists.

Journal: The Journal of pharmacology and experimental therapeutics20050601

Title: Evidence for a selective prefrontal cortical GABA(B) receptor-mediated inhibition of glutamate release in the ventral tegmental area: a dual probe microdialysis study in the awake rat.

Journal: Neuroscience20050101

Title: Mechanisms underlying the sympathomimetic cardiovascular responses elicited by gamma-hydroxybutyrate.

Journal: Journal of cardiovascular pharmacology20041201

Title: Pentobarbital induces thalamic oscillations in brain slices, modulated by GABA and glycine receptors.

Journal: Neuropharmacology20041201

Title: The effects of intraperitoneal and intracerebroventricular administration of the GABAB receptor antagonist CGP 35348 on food intake in rats.

Journal: European journal of pharmacology20041025

Title: Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats.

Journal: Brain research bulletin20040930

Title: Evidence for a differential medial prefrontal dopamine D1 and D2 receptor regulation of local and ventral tegmental glutamate and GABA release: a dual probe microdialysis study in the awake rat.

Journal: Brain research20040813

Title: Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons.

Journal: Neuron20040624

Title: Nigral GABAergic inhibition upon mesencephalic dopaminergic cell groups in rats.

Journal: The European journal of neuroscience20040501

Title: Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors.

Journal: The Journal of pharmacology and experimental therapeutics20040301

Title: Mechanisms and significance of reduced activity and responsiveness in resting frog tadpoles.

Journal: The Journal of experimental biology20040301

Title: Isoflurane facilitates hiccup-like reflex through gamma aminobutyric acid (GABA)A- and suppresses through GABAB-receptors in pentobarbital-anesthetized cats.

Journal: Anesthesia and analgesia20040201

Title: Effects of gamma-hydroxybutyrate (GHB) on schedule-controlled responding in rats: role of GHB and GABAB receptors.

Journal: The Journal of pharmacology and experimental therapeutics20040101

Title: GABA(B) receptor activation and limbic network ictogenesis.

Journal: Neuropharmacology20040101

Title: Does gabapentin act as an agonist at native GABA(B) receptors?

Journal: Journal of biomedical science20040101

Title: Contribution of GABA(B) receptor-mediated inhibition to the expression and termination of group I mGluR-induced ictaform bursts.

Journal: Epilepsy research20040101

Title: Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation.

Journal: The European journal of neuroscience20031201

Title: Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.

Journal: Journal of neurochemistry20031101

Title: Inhibitory effects of spinal baclofen on spinal dorsal horn neurones in inflamed and neuropathic rats in vivo.

Journal: Brain research20031010

Title: Baclofen inhibits guinea pig magnocellular neurones via activation of an inwardly rectifying K+ conductance.

Journal: The Journal of physiology20030815

Title: Treatment of spontaneous and chemically induced EEG paroxysms in the Fischer-344 rat with traditional antiepileptic drugs or AED+CGP 35348 polytherapy.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20030801

Title: Hindquarters vasoconstriction through central GABA(B) receptors in conscious rats.

Journal: Experimental physiology20030701

Title: The anaesthetic agent propofol interacts with GABA(B)-receptors: an electrophysiological study in rat.

Journal: Life sciences20030502

Title: Identified sources and targets of slow inhibition in the neocortex.

Journal: Science (New York, N.Y.)20030321

Title: The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic system.

Journal: Neuroscience20030101

Title: Action of GABA-B antagonist on cortical epileptic afterdischarges in rats is similar to that of GABA-A antagonist.

Journal: Physiological research20030101

Title: Modulation of the components of the rat dark-adapted electroretinogram by the three subtypes of GABA receptors.

Journal: Visual neuroscience20030101

Title: Epileptiform synchronization and GABA(B) receptor antagonism in the juvenile rat hippocampus.

Journal: The Journal of pharmacology and experimental therapeutics20021201

Title: Effects of intrahippocampal injection of GABAergic drugs on memory retention of passive avoidance learning in rats.

Journal: Journal of psychopharmacology (Oxford, England)20021201

Title: Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists.

Journal: Neuropharmacology20020901

Title: Gamma-aminobutyric acid circuits shape response properties of auditory cortex neurons.

Journal: Brain research20020719

Title: Synchronized oscillations caused by disinhibition in rodent neocortex are generated by recurrent synaptic activity mediated by AMPA receptors.

Journal: The Journal of physiology20020715

Title: Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria).

Journal: The Journal of pharmacology and experimental therapeutics20020701

Title: International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function.

Journal: Pharmacological reviews20020601

Title: Long-term potentiation alters the modulator pharmacology of AMPA-type glutamate receptors.

Journal: Journal of neurophysiology20020601

Title: GABA-B-related activity in processing of transcallosal response in cat motor cortex.

Journal: Journal of neuroscience research20020515

Title: The effects of fruit essential oil of the Pimpinella anisum on acquisition and expression of morphine induced conditioned place preference in mice.

Journal: Journal of ethnopharmacology20020401

Title: GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20020301

Title: Effect of intracerebroventricular injection of GABA receptor agents on morphine-induced antinociception in the formalin test.

Journal: Journal of psychopharmacology (Oxford, England)20020301

Title: Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20011101

Title: Spinal GABA(B)-receptor antagonism increases nociceptive transmission in vivo.

Journal: Neuroreport20011029

Title: Evidence for a role for GABA(A) and NMDA receptors in ethanol inhibition of long-term potentiation.

Journal: Brain research. Molecular brain research20011019

Title: Opioid and GABA receptors involved in mediation and modulation of tonic and stimulus-evoked inhibition of a spinal reflex in the decerebrated and spinalized rabbit.

Journal: Neuropharmacology20010901

Title: Network and intrinsic contributions to carbachol-induced oscillations in the rat subiculum.

Journal: Journal of neurophysiology20010901

Title: GABA(B) and NMDA receptors contribute to spindle-like oscillations in rat thalamus in vitro.

Journal: Journal of neurophysiology20010901

Title: gamma-Hydroxybutyrate modulation of glutamate levels in the hippocampus: an in vivo and in vitro study.

Journal: Journal of neurochemistry20010901

Title: GABA mechanisms and antinociception in mice with ligated sciatic nerve.

Journal: Pharmacology & toxicology20010801

Title: Developmental characteristics of epileptiform activity in immature rat neocortex: a comparison of four in vitro seizure models.

Journal: Brain research. Developmental brain research20010629

Title: GABA(A)-dependent chloride influx modulates reversal potential of GABA(B)-mediated IPSPs in hippocampal pyramidal cells.

Journal: Journal of neurophysiology20010601

Title: Heterogeneous susceptibility of GABA(A) receptor-mediated IPSCs to depolarization-induced suppression of inhibition in rat hippocampus.

Journal: The Journal of physiology20010501

Title: Gamma-vinyl GABA reduces paired pulse inhibition in the rat dentate gyrus in vivo and in vitro.

Journal: Epilepsy research20010501

Title: Short-term plasticity at inhibitory synapses in rat striatum and its effects on striatal output.

Journal: Journal of neurophysiology20010501

Title: Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons.

Journal: Neuroreport20010212

Title: Multireceptor GABAergic regulation of synaptic communication in amphibian retina.

Journal: The Journal of physiology20010101

Title: GABA(A) but not GABA(B) receptor stimulation induces antianxiety profile in rats.

Journal: Pharmacology, biochemistry, and behavior20010101

Title: The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.

Journal: British journal of pharmacology20001101

Title: Inhibition of catechol-O-methyltransferase (COMT) in the brain does not affect the action of dopamine and levodopa: an in vitro electrophysiological evidence from rat mesencephalic dopamine neurons.

Journal: Journal of neural transmission (Vienna, Austria : 1996)19990101

Title: Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

Journal: Nature19970320

Title: CGP 35348 and CGP 55845A block the baclofen-induced depression of dorsal root evoked potentials in lumbar motoneurons of the neonatal rat.

Journal: Neuroscience letters19960823

Title: Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.

Journal: The Journal of pharmacology and experimental therapeutics19950901

Title: Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.

Journal: Journal of medicinal chemistry19950818

Title: Antagonism of baclofen-induced depression of whole-cell synaptic currents in spinal dorsal horn neurones by the potent GABAB antagonist CGP55845.

Journal: Neuropharmacology19931201

Title: Reversal of scopolamine-induced amnesia by the GABAB receptor antagonist CGP 35348 in the mouse.

Journal: Brain research. Cognitive brain research19930401

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