123691-14-5,MFCD00910404
Catalog No.:AA000KVL

123691-14-5 | Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-

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  • Technical Information
  • Properties
  • Literature
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  • Download SDS
Technical Information
Catalog Number:
AA000KVL
Chemical Name:
Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-
CAS Number:
123691-14-5
Molecular Formula:
C10H22NO2P
Molecular Weight:
219.2609
MDL Number:
MFCD00910404
SMILES:
NCCCP(=O)(CC1CCCCC1)O
Properties
Computed Properties
 
Complexity:
202  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1.6  

Literature

Title: gamma-Aminobutyric acid-mediated regulation of the activity-dependent olfactory bulb dopaminergic phenotype.

Journal: Journal of neuroscience research 20090801

Title: Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures.

Journal: Molecular pharmacology 20090701

Title: Synaptic properties of the mammillary and cortical afferents to the anterodorsal thalamic nucleus in the mouse.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617

Title: Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation.

Journal: Journal of neurophysiology 20060901

Title: GABAB-receptor-mediated suppression of sympathetic outflow from the spinal cord of neonatal rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20051101

Title: Mapping by laser photostimulation of connections between the thalamic reticular and ventral posterior lateral nuclei in the rat.

Journal: Journal of neurophysiology 20051001

Title: Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord.

Journal: The Journal of pharmacology and experimental therapeutics 20050201

Title: GABA(B) receptor agonists reverse akinesia following intranigral or intracerebroventricular injection in the reserpine-treated rat.

Journal: British journal of pharmacology 20030802

Title: GABA(B) receptor inhibition causes locomotor stimulation in mice.

Journal: European journal of pharmacology 20011214

Title: Attenuation of morphine withdrawal signs by the GABA(B) receptor agonist baclofen.

Journal: Life sciences 20011214

Title: Repeated administration of CGP 46381, a gamma-aminobutyric acidB antagonist, and ethosuximide suppresses seizure-associated cyclic adenosine 3'5' monophosphate response element- and activator protein-1 DNA-binding activities in lethargic (lh/lh) mice.

Journal: Neuroscience letters 20010119

Title: The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.

Journal: British journal of pharmacology 20001101

Title: Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.

Journal: The Journal of pharmacology and experimental therapeutics 19950901

Title: Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.

Journal: Journal of medicinal chemistry 19950818

Title: The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro.

Journal: European journal of pharmacology 19930323

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SDS
Tags:123691-14-5 Molecular Formula|123691-14-5 MDL|123691-14-5 SMILES|123691-14-5 Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-
Catalog No.: AA000KVL
123691-14-5,MFCD00910404
123691-14-5 | Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-
This product is typically in stock,please click "Inquire" below or contact us at [email protected]for pricing and availability information.
Inquire
Technical Information
Catalog Number: AA000KVL
Chemical Name: Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-
CAS Number: 123691-14-5
Molecular Formula: C10H22NO2P
Molecular Weight: 219.2609
MDL Number: MFCD00910404
SMILES: NCCCP(=O)(CC1CCCCC1)O
Properties
Complexity: 202  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 14  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1.6  
Literature fold

Title: gamma-Aminobutyric acid-mediated regulation of the activity-dependent olfactory bulb dopaminergic phenotype.

Journal: Journal of neuroscience research20090801

Title: Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures.

Journal: Molecular pharmacology20090701

Title: Synaptic properties of the mammillary and cortical afferents to the anterodorsal thalamic nucleus in the mouse.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090617

Title: Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation.

Journal: Journal of neurophysiology20060901

Title: GABAB-receptor-mediated suppression of sympathetic outflow from the spinal cord of neonatal rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20051101

Title: Mapping by laser photostimulation of connections between the thalamic reticular and ventral posterior lateral nuclei in the rat.

Journal: Journal of neurophysiology20051001

Title: Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord.

Journal: The Journal of pharmacology and experimental therapeutics20050201

Title: GABA(B) receptor agonists reverse akinesia following intranigral or intracerebroventricular injection in the reserpine-treated rat.

Journal: British journal of pharmacology20030802

Title: GABA(B) receptor inhibition causes locomotor stimulation in mice.

Journal: European journal of pharmacology20011214

Title: Attenuation of morphine withdrawal signs by the GABA(B) receptor agonist baclofen.

Journal: Life sciences20011214

Title: Repeated administration of CGP 46381, a gamma-aminobutyric acidB antagonist, and ethosuximide suppresses seizure-associated cyclic adenosine 3'5' monophosphate response element- and activator protein-1 DNA-binding activities in lethargic (lh/lh) mice.

Journal: Neuroscience letters20010119

Title: The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.

Journal: British journal of pharmacology20001101

Title: Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.

Journal: The Journal of pharmacology and experimental therapeutics19950901

Title: Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.

Journal: Journal of medicinal chemistry19950818

Title: The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro.

Journal: European journal of pharmacology19930323

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