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125404-04-8,MFCD18642664
Catalog No.:AA009F99

125404-04-8 | TCN 238

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98% by HPLC
in stock  
$88.00   $61.00
- +
5mg
≥98%
in stock  
$139.00   $97.00
- +
10mg
≥98%
in stock  
$263.00   $184.00
- +
25mg
≥98%
in stock  
$619.00   $433.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA009F99
Chemical Name:
TCN 238
CAS Number:
125404-04-8
Molecular Formula:
C12H11N3
Molecular Weight:
197.2358
MDL Number:
MFCD18642664
SMILES:
Nc1nccc(n1)/C=C/c1ccccc1
Properties
Computed Properties
 
Complexity:
209  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.2  

Literature

Title: Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Journal: Journal of medicinal chemistry 20110728

Title: An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.

Journal: Bioorganic & medicinal chemistry letters 20100815

Title: East SP, et al. An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4901-5.

Title: Pershina EV, et al. Subacute activation of mGlu4 receptors causes the feedback inhibition of its gene expression in rat brain. Life Sci. 2016 May 15;153:50-4.

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SDS
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Tags:125404-04-8 Molecular Formula|125404-04-8 MDL|125404-04-8 SMILES|125404-04-8 TCN 238
Catalog No.: AA009F99
125404-04-8,MFCD18642664
125404-04-8 | TCN 238
Pack Size： 1mg
Purity： 98% by HPLC
in stock
$88.00 $61.00
Pack Size： 5mg
Purity： ≥98%
in stock
$139.00 $97.00
Pack Size： 10mg
Purity： ≥98%
in stock
$263.00 $184.00
Pack Size： 25mg
Purity： ≥98%
in stock
$619.00 $433.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA009F99
Chemical Name: TCN 238
CAS Number: 125404-04-8
Molecular Formula: C12H11N3
Molecular Weight: 197.2358
MDL Number: MFCD18642664
SMILES: Nc1nccc(n1)/C=C/c1ccccc1
Properties
Complexity: 209  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 15  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.2  
Literature fold

Title: Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Journal: Journal of medicinal chemistry20110728

Title: An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.

Journal: Bioorganic & medicinal chemistry letters20100815

Title: East SP, et al. An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4901-5.

Title: Pershina EV, et al. Subacute activation of mGlu4 receptors causes the feedback inhibition of its gene expression in rat brain. Life Sci. 2016 May 15;153:50-4.

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