Title: Tolfenamic acid downregulates BACE1 and protects against lead-induced upregulation of Alzheimer's disease related biomarkers.
Journal: Neuropharmacology20140401
Title: Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.
Journal: Chemico-biological interactions20130225
Title: Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer.
Journal: The Prostate20121101
Title: Simultaneous determination of mefenamic and tolfenamic acids in real samples by terbium-sensitized luminescence.
Journal: Journal of fluorescence20121101
Title: Structure-activity relationship of fenamates as Slo2.1 channel activators.
Journal: Molecular pharmacology20121101
Title: Raman and IR spectroscopic studies of fenamates--conformational differences in polymorphs of flufenamic acid, mefenamic acid and tolfenamic acid.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20121001
Title: Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver.
Journal: Integrative biology : quantitative biosciences from nano to macro20120921
Title: Development and validation of two multiresidue liquid chromatography tandem mass spectrometry methods based on a versatile extraction procedure for isolating non-steroidal anti-inflammatory drugs from bovine milk and muscle tissue.
Journal: Analytical and bioanalytical chemistry20120901
Title: Determination of non-steroidal anti-inflammatory drugs and their metabolites in milk by liquid chromatography-tandem mass spectrometry.
Journal: Analytical and bioanalytical chemistry20120701
Title: Structural features of mono- and tri-nuclear Zn(II) complexes with a non-steroidal anti-inflammatory drug as ligand.
Journal: Dalton transactions (Cambridge, England : 2003)20120621
Title: Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.
Journal: Investigational new drugs20120601
Title: Italian guidelines for primary headaches: 2012 revised version.
Journal: The journal of headache and pain20120501
Title: Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis.
Journal: Journal of natural products20120427
Title: Evaluating the effects of 14-day oral vedaprofen and tolfenamic acid treatment on renal function, hematological and biochemical profiles in healthy cats.
Journal: Journal of veterinary pharmacology and therapeutics20120201
Title: Polymorph formation and nucleation mechanism of tolfenamic acid in solution: an investigation of pre-nucleation solute association.
Journal: Pharmaceutical research20120201
Title: Cobalt(II) complexes with non-steroidal anti-inflammatory drug tolfenamic acid: Structure and biological evaluation.
Journal: European journal of medicinal chemistry20120201
Title: Activating transcription factor 3 and the nervous system.
Journal: Frontiers in molecular neuroscience20120101
Title: Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: involvement of NAG-1 expression.
Journal: PloS one20120101
Title: Effect of tolfenamic acid on canine cancer cell proliferation, specificity protein (sp) transcription factors, and sp-regulated proteins in canine osteosarcoma, mammary carcinoma, and melanoma cells.
Journal: Journal of veterinary internal medicine20120101
Title: Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer.
Journal: PloS one20120101
Title: Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy.
Journal: Current medicinal chemistry20120101
Title: Anti-inflammatory drugs and prediction of new structures by comparative analysis.
Journal: Anti-inflammatory & anti-allergy agents in medicinal chemistry20120101
Title: 9,10-phenanthrenequinone induces monocytic differentiation of U937 cells through regulating expression of aldo-keto reductase 1C3.
Journal: Biological & pharmaceutical bulletin20120101
Title: The ability of tolfenamic acid to penetrate the brain: a model for testing the brain disposition of candidate Alzheimer's drugs using multiple platforms.
Journal: Current Alzheimer research20111201
Title: Interplay between molecular conformation and intermolecular interactions in conformational polymorphism: a molecular perspective from electronic calculations of tolfenamic acid.
Journal: International journal of pharmaceutics20111014
Title: Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase.
Journal: The Journal of pharmacology and experimental therapeutics20111001
Title: Development and validation of a confirmatory method for the determination of 12 non steroidal anti-inflammatory drugs in milk using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. A20110916
Title: Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in calves.
Journal: Journal of veterinary pharmacology and therapeutics20110801
Title: Optimization of the derivatization reaction and the solid-phase microextraction conditions using a D-optimal design and three-way calibration in the determination of non-steroidal anti-inflammatory drugs in bovine milk by gas chromatography-mass spectrometry.
Journal: Journal of chromatography. A20110715
Title: Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma.
Journal: Oral diseases20110701
Title: Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors.
Journal: Gynecologic oncology20110701
Title: Tolfenamic acid interrupts the de novo synthesis of the β-amyloid precursor protein and lowers amyloid beta via a transcriptional pathway.
Journal: Current Alzheimer research20110601
Title: Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.
Journal: Chemico-biological interactions20110530
Title: Apoptotic effect of tolfenamic acid in androgen receptor-independent prostate cancer cell and xenograft tumor through specificity protein 1.
Journal: Cancer science20110401
Title: Combined treatment of pancreatic cancer with mithramycin a and tolfenamic Acid promotes sp1 degradation and synergistic antitumor activity--letter.
Journal: Cancer research20110401
Title: Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1.
Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)20110301
Title: Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice.
Journal: Investigational new drugs20110201
Title: Therapeutic applications of NSAIDS in cancer: special emphasis on tolfenamic acid.
Journal: Frontiers in bioscience (Scholar edition)20110101
Title: Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: case report.
Journal: Acta veterinaria Scandinavica20110101
Title: Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?
Journal: BMC neurology20110101
Title: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.
Journal: BMC cancer20110101
Title: Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.
Journal: PloS one20110101
Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
Journal: Healthcare informatics research20101201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters20101101
Title: Postoperative analgesic efficacy of meloxicam compared to tolfenamic acid in cats undergoing orthopaedic surgery.
Journal: The Journal of small animal practice20101001
Title: Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways.
Journal: Oncogene20100916
Title: Occurrence and risk assessment of acidic pharmaceuticals in the Yellow River, Hai River and Liao River of north China.
Journal: The Science of the total environment20100715
Title: Analytical strategy for the determination of non-steroidal anti-inflammatory drugs in plasma and improved analytical strategy for the determination of authorized and non-authorized non-steroidal anti-inflammatory drugs in milk by LC-MS/MS.
Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment20100701
Title: Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway.
Journal: Journal of clinical biochemistry and nutrition20100701
Title: Novel milk-based oral formulations: proof of concept.
Journal: International journal of pharmaceutics20100510
Title: Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in goats.
Journal: Veterinary journal (London, England : 1997)20100501
Title: Confirmatory analysis of non-steroidal anti-inflammatory drugs in bovine milk by high-performance liquid chromatography with fluorescence detection.
Journal: Journal of chromatography. A20100423
Title: Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.
Journal: Dalton transactions (Cambridge, England : 2003)20100321
Title: Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity.
Journal: Cancer research20100201
Title: Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial.
Journal: BMJ (Clinical research ed.)20100101
Title: Thermodynamic and structural study of tolfenamic acid polymorphs.
Journal: Journal of pharmaceutical and biomedical analysis20091205
Title: Development of a rapid, multi-class method for the confirmatory analysis of anti-inflammatory drugs in bovine milk using liquid chromatography tandem mass spectrometry.
Journal: Journal of chromatography. A20091113
Title: Eicosanoids influence insect susceptibility to nucleopolyhedroviruses.
Journal: Journal of invertebrate pathology20091101
Title: Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met.
Journal: Carcinogenesis20090701
Title: Anti-inflammatory, antiproliferative, and radical-scavenging activities of tolfenamic acid and its metal complexes.
Journal: Chemistry & biodiversity20090601
Title: The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression.
Journal: Molecular cancer therapeutics20090501
Title: The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury.
Journal: Toxicology letters20090425
Title: Polymer-induced heteronucleation of tolfenamic acid: structural investigation of a pentamorph.
Journal: Journal of the American Chemical Society20090408
Title: Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression.
Journal: Molecular cancer therapeutics20090301
Title: Thermodynamics of lipophilic drug binding to intestinal fatty acid binding protein and permeation across membranes.
Journal: Molecular pharmaceutics20090101
Title: Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification.
Journal: Breast cancer research : BCR20090101
Title: Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.
Journal: Retrovirology20090101
Title: ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells.
Journal: Molecular cancer therapeutics20081201
Title: Current migraine management - patient acceptability and future approaches.
Journal: Neuropsychiatric disease and treatment20081201
Title: Efficacy of tolfenamic acid and meloxicam in the control of postoperative pain following ovariohysterectomy in the cat.
Journal: Veterinary anaesthesia and analgesia20081101
Title: Assessment of the duration of the pain response associated with lameness in dairy cows, and the influence of treatment.
Journal: New Zealand veterinary journal20081001
Title: Optimizing prophylactic treatment of migraine: Subtypes and patient matching.
Journal: Therapeutics and clinical risk management20081001
Title: Poloxamer 407 as a solubilising agent for tolfenamic acid and as a base for a gel formulation.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20080902
Title: Effects of meloxicam or tolfenamic acid administration on the pain and stress responses of Merino lambs to mulesing.
Journal: Australian veterinary journal20080801
Title: In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions.
Journal: Basic & clinical pharmacology & toxicology20080801
Title: Effects of fenamate on inhibitory postsynaptic currents in Purkinje's cells.
Journal: Bulletin of experimental biology and medicine20080501
Title: catena-Poly[[bis-[2-(2,3-dimethyl-anilino)benzoato-κO]cadmium(II)]-di-μ-3-pyridylmethanol-κN:O;κO:N].
Journal: Acta crystallographica. Section E, Structure reports online20080301
Title: The effect of suspended particles coated by humic acid on the toxicity of pharmaceuticals, estrogens, and phenolic compounds.
Journal: Environment international20080201
Title: Confirmatory identification of sixteen non-steroidal anti-inflammatory drug residues in raw milk by liquid chromatography coupled with ion trap mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20080101
Title: Field evaluation of the efficacy of tolfenamic acid administered in one single preoperative injection for the prevention of postoperative pain in the dog.
Journal: Journal of veterinary pharmacology and therapeutics20071201
Title: Inhibition of human thiopurine S-methyltransferase by various nonsteroidal anti-inflammatory drugs in vitro: a mechanism for possible drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals20070901
Title: Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation.
Journal: European journal of clinical pharmacology20070901
Title: Nonsteroidal anti-inflammatory drugs in cats: a review.
Journal: Veterinary anaesthesia and analgesia20070701
Title: Eicosanoid biosynthesis inhibitors increase the susceptibility of Lymantria dispar to nucleopolyhedrovirus LdMNPV.
Journal: Journal of invertebrate pathology20070601
Title: Acute migraine: Current treatment and emerging therapies.
Journal: Therapeutics and clinical risk management20070601
Title: Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.
Journal: Cancer research20070401
Title: Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
Journal: The Journal of biological chemistry20070316
Title: Rapid method for the determination of non-steroidal anti-inflammatory drugs in animal tissue by liquid chromatography-mass spectrometry with ion-trap detector.
Journal: Analytica chimica acta20070314
Title: Characterization and physical stability of tolfenamic acid-PVP K30 solid dispersions.
Journal: Pharmaceutical development and technology20070101
Title: The use of combination therapies in the acute management of migraine.
Journal: Neuropsychiatric disease and treatment20060901
Title: Nutraceutical inhibitors of urokinase: potential applications in prostate cancer prevention and treatment.
Journal: Oncology reports20060801
Title: Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation.
Journal: Journal of the National Cancer Institute20060621
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501
Title: Involvement of opioidergic and alpha2-adrenergic mechanisms in the central analgesic effects of non-steroidal anti-inflammatory drugs in sheep.
Journal: Research in veterinary science20060401
Title: Pharmacokinetic and pharmacodynamic interactions of tolfenamic acid and marbofloxacin in goats.
Journal: Research in veterinary science20060201
Title: Determination of fourteen non-steroidal anti-inflammatory drugs in animal serum and plasma by liquid chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20060101
Title: Multi-residue determination of non-steroidal anti-inflammatory drug residues in animal serum and plasma by HPLC and photo-diode array detection.
Journal: Journal of chromatographic science20060101
Title: Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials.
Journal: BMJ (Clinical research ed.)20051224
Title: Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile.
Journal: Bioorganic & medicinal chemistry20051201
Title: Study of structural features and thermodynamic parameters, determining the chromatographic behaviour of drug-cyclodextrin complexes.
Journal: Journal of chromatography. A20050916
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology20050601
Title: Geriatric pharmacology.
Journal: The Veterinary clinics of North America. Small animal practice20050501
Title: Infrared studies of the polymorphic states of the fenamates.
Journal: Journal of pharmaceutical and biomedical analysis20050309
Title: Influence of marbofloxacin on the pharmacokinetics and pharmacodynamics of tolfenamic acid in calves.
Journal: Journal of veterinary pharmacology and therapeutics20050201
Title: PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology.
Journal: Journal of veterinary pharmacology and therapeutics20041201
Title: Compounds exhibiting selective efficacy for different beta subunits of human recombinant gamma-aminobutyric acid A receptors.
Journal: The Journal of pharmacology and experimental therapeutics20041101
Title: Pain management in cats--past, present and future. Part 2. Treatment of pain--clinical pharmacology.
Journal: Journal of feline medicine and surgery20041001
Title: Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Journal: Bioorganic & medicinal chemistry letters20040716
Title: Attitudes and concerns of French veterinarians towards pain and analgesia in dogs and cats.
Journal: Veterinary anaesthesia and analgesia20040701
Title: Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs.
Journal: American journal of veterinary research20040601
Title: Migraine headache.
Journal: Clinical evidence20040601
Title: Binuclear copper(II) complexes of tolfenamic: synthesis, crystal structure, spectroscopy and superoxide dismutase activity.
Journal: Journal of inorganic biochemistry20040201
Title: Acute treatment of migraine. Breaking the paradigm of monotherapy.
Journal: BMC neurology20040101
Title: Rizatriptan versus rizatriptan plus rofecoxib versus rizatriptan plus tolfenamic acid in the acute treatment of migraine.
Journal: BMC neurology20040101
Title: Multi-residue liquid chromatography/tandem mass spectrometry method for the detection of non-steroidal anti-inflammatory drugs in bovine muscle: optimisation of ion trap parameters.
Journal: Rapid communications in mass spectrometry : RCM20040101
Title: Migraine headache.
Journal: Clinical evidence20031201
Title: Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study.
Journal: British journal of cancer20030602
Title: Determination of acidic drugs in sewage water by gas chromatography-mass spectrometry as tert.-butyldimethylsilyl derivatives.
Journal: Journal of chromatography. A20030124
Title: [Neurotransmitter mechanism of the tropoxin effect in comparison with other antimigraine preparations].
Journal: Eksperimental'naia i klinicheskaia farmakologiia20030101
Title: [Effectiveness of tolfenamic acid in the prevention of migraine].
Journal: Medicina (Kaunas, Lithuania)20020101
Title: Search of antimicrobial activity of selected non-antibiotic drugs.
Journal: Acta poloniae pharmaceutica20020101
Title: Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Journal: Chemical communications (Cambridge, England)20011121
Title: Fenamates stimulate BKCa channel osteoblast-like MG-63 cells activity in the human.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research20011101
Title: Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug.
Journal: Arquivos de neuro-psiquiatria20010901
Title: Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.
Journal: Journal of analytical toxicology20010101
Title: A nonsteroidal anti-inflammatory drug, flufenamic acid, inhibits the expression of the androgen receptor in LNCaP cells.
Journal: Endocrinology19991101
Title: Human pharmacokinetics of tolfenamic acid, a new anti-inflammatory agent.
Journal: European journal of clinical pharmacology19810101
Title: Kay-Mugford P, et al. In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs. Am J Vet Res. 2000 Jul;61(7):802-10.
Title: Maliakal P, et al. Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats. Invest New Drugs. 2012 Jun;30(3):853-61.
Title: Sankpal UT, et al. Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells. Oncotarget. 2017 Feb 28;8(9):14593-14603
