Name: Name:2-Amino-2-(2H-tetrazol-5-yl)acetic acid
Brand: AABLOCKS
SKU: AA00186R
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00186R

Chemical Name: 2-Amino-2-(2H-tetrazol-5-yl)acetic acid

CAS Number: 138199-51-6

Molecular Formula: C3H5N5O2

Molecular Weight: 143.1041

MDL Number: MFCD00233633

SMILES: OC(=O)C(c1n[nH]nn1)N

Properties

Storage: 2-8℃;

Complexity: 139

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 10

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 1

Undefined Bond Stereocenter Count: 0

XLogP3: -4.1

Literature fold

Title: Seizure responses and induction of Fos by the NMDA agonist (tetrazol-5-yl)glycine in a genetic model of NMDA receptor hypofunction.

Journal: Brain research20080724

Title: Pharmacological characterization of ligands at recombinant NMDA receptor subtypes by electrophysiological recordings and intracellular calcium measurements.

Journal: Combinatorial chemistry & high throughput screening20080501

Title: Assessment of NMDA receptor activation in vivo by Fos induction after challenge with the direct NMDA agonist (tetrazol-5-yl)glycine: effects of clozapine and haloperidol.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20070701

Title: Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist.

Journal: Bioorganic & medicinal chemistry20010201

Title: Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.

Journal: Neurochemistry international20010101

Title: Schoepp DD, et al. D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist. Eur J Pharmacol. 1991 Oct 15;203(2):237-43.

Title: Vance KM, et al. Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors. Nat Commun. 2011;2:294.

Title: Duncan GE, et al. Seizure responses and induction of Fos by the NMDA agonist (tetrazol-5-yl)glycine in a geneticmodel of NMDA receptor hypofunction. Brain Res. 2008 Jul 24;1221:41-8.

138199-51-6 | 2-Amino-2-(2H-tetrazol-5-yl)acetic acid