Name: Name:2-Chloro-1-methylpyridinium iodide
Brand: AABLOCKS
SKU: AA007YUD
Rating: 90 (10 reviews)

2-Chloro-1-methylpyridinium iodide, commonly known as the Mukaiyama reagent, is a versatile compound widely employed in organic synthesis due to its ability to activate hydroxy groups in alcohols and carboxylic acids. This reagent facilitates the synthesis of various derivatives including esters, lactones, amides, lactams, and ketenes from their corresponding carboxylic acids. Additionally, it serves as an efficient coupling reagent in peptide synthesis, offering advantages such as low toxicity, straightforward reaction conditions, and cost-effectiveness compared to alternatives like EDC. In applications beyond organic synthesis, 2-Chloro-1-methylpyridinium iodide finds utility as a dehydrating agent for converting aldoximes to nitriles and alcohols to alkyl thiocyanates. Moreover, it serves as a cross-linking agent for producing biodegradable cross-linked hyaluronic acid film and gelatin membranes, offering potential in biomedical applications. Furthermore, it acts as a condensing agent in the synthesis of various β-lactams from β-amino acids, showcasing its versatility in diverse chemical processes.

Catalog No.: AA007YUD

14338-32-0 | 2-Chloro-1-methylpyridinium iodide

Pack Size： 5g

Purity： 98%(HPLC)

in stock

$24.00 $17.00

Pack Size： 25g

Purity： 98%

in stock

$51.00 $36.00

Pack Size： 100g

Purity： 98%

in stock

$135.00 $95.00

Pack Size： 500g

Purity： 98%

in stock

$527.00 $369.00

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Technical Information

Catalog Number: AA007YUD

Chemical Name: 2-Chloro-1-methylpyridinium iodide

CAS Number: 14338-32-0

Molecular Formula: C6H7ClIN

Molecular Weight: 255.4839

MDL Number: MFCD00011984

SMILES: Clc1cccc[n+]1C.[I-]

NSC Number: 200739

Properties

Complexity: 74.9

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 9

Hydrogen Bond Acceptor Count: 1

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

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Application fold

2-Chloro-1-methylpyridinium iodide, commonly known as the Mukaiyama reagent, is a versatile compound widely employed in organic synthesis due to its ability to activate hydroxy groups in alcohols and carboxylic acids. This reagent facilitates the synthesis of various derivatives including esters, lactones, amides, lactams, and ketenes from their corresponding carboxylic acids. Additionally, it serves as an efficient coupling reagent in peptide synthesis, offering advantages such as low toxicity, straightforward reaction conditions, and cost-effectiveness compared to alternatives like EDC.

In applications beyond organic synthesis, 2-Chloro-1-methylpyridinium iodide finds utility as a dehydrating agent for converting aldoximes to nitriles and alcohols to alkyl thiocyanates. Moreover, it serves as a cross-linking agent for producing biodegradable cross-linked hyaluronic acid film and gelatin membranes, offering potential in biomedical applications. Furthermore, it acts as a condensing agent in the synthesis of various β-lactams from β-amino acids, showcasing its versatility in diverse chemical processes.

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