145307-34-2,MFCD03107804
Catalog No.:AA001KPD

145307-34-2 | 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
≥98%
in stock  
$230.00   $161.00
- +
10mg
≥98%
in stock  
$336.00   $235.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001KPD
Chemical Name:
1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
CAS Number:
145307-34-2
Molecular Formula:
C20H28ClNO3
Molecular Weight:
365.8942
MDL Number:
MFCD03107804
SMILES:
NCC1OC(Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3.Cl
Properties
Computed Properties
 
Complexity:
454  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats.

Journal: The international journal of neuropsychopharmacology 20090801

Title: Neonatal tactile stimulation enhances spatial working memory, prefrontal long-term potentiation, and D1 receptor activation in adult rats.

Journal: Neurobiology of learning and memory 20080501

Title: Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors.

Journal: Neuropharmacology 20070201

Title: Effect of dopamine D1 receptor antagonist SCH23390 and D1 agonist A77636 on active allothetic place avoidance, a spatial cognition task.

Journal: Behavioural brain research 20060925

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats.

Journal: European journal of pharmacology 20060227

Title: Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists.

Journal: Molecular pharmacology 20051001

Title: Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions.

Journal: Biological psychiatry 20050601

Title: Negative feedback regulation of nigrostriatal dopamine release: mediation by striatal D1 receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020201

Title: Comparison of interactions of D1-like agonists, SKF 81297, SKF 82958 and A-77636, with cocaine: locomotor activity and drug discrimination studies in rodents.

Journal: Psychopharmacology 20020101

Title: Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats.

Journal: Psychopharmacology 20010401

Title: Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D(1) dopamine receptors in the rat.

Journal: Brain research 20010302

Title: Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys.

Journal: Neurology 19970801

Title: Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo.

Journal: Journal of medicinal chemistry 19970523

Title: Chronic L-DOPA administration induces dyskinesias in the 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-treated common marmoset (Callithrix Jacchus).

Journal: Movement disorders : official journal of the Movement Disorder Society 19951101

Title: Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 19931001

Title: Kebabian JW, et al. A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets. Eur J Pharmacol. 1992;229(2-3):203-209.

Title: Smith LA, et al. The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration. J Neural Transm (Vienna). 2002;109(2):123-140.

Title: Cooper SJ, et al. The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats. Eur J Pharmacol. 2006;532(3):253-257.

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Tags:145307-34-2 Molecular Formula|145307-34-2 MDL|145307-34-2 SMILES|145307-34-2 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
Catalog No.: AA001KPD
145307-34-2,MFCD03107804
145307-34-2 | 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
Pack Size: 1mg
Purity: ≥98%
in stock
$63.00 $44.00
Pack Size: 5mg
Purity: ≥98%
in stock
$230.00 $161.00
Pack Size: 10mg
Purity: ≥98%
in stock
$336.00 $235.00
Quantity
- +
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Technical Information
Catalog Number: AA001KPD
Chemical Name: 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
CAS Number: 145307-34-2
Molecular Formula: C20H28ClNO3
Molecular Weight: 365.8942
MDL Number: MFCD03107804
SMILES: NCC1OC(Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3.Cl
Properties
Complexity: 454  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats.

Journal: The international journal of neuropsychopharmacology20090801

Title: Neonatal tactile stimulation enhances spatial working memory, prefrontal long-term potentiation, and D1 receptor activation in adult rats.

Journal: Neurobiology of learning and memory20080501

Title: Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors.

Journal: Neuropharmacology20070201

Title: Effect of dopamine D1 receptor antagonist SCH23390 and D1 agonist A77636 on active allothetic place avoidance, a spatial cognition task.

Journal: Behavioural brain research20060925

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats.

Journal: European journal of pharmacology20060227

Title: Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists.

Journal: Molecular pharmacology20051001

Title: Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions.

Journal: Biological psychiatry20050601

Title: Negative feedback regulation of nigrostriatal dopamine release: mediation by striatal D1 receptors.

Journal: The Journal of pharmacology and experimental therapeutics20041001

Title: The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20020201

Title: Comparison of interactions of D1-like agonists, SKF 81297, SKF 82958 and A-77636, with cocaine: locomotor activity and drug discrimination studies in rodents.

Journal: Psychopharmacology20020101

Title: Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats.

Journal: Psychopharmacology20010401

Title: Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D(1) dopamine receptors in the rat.

Journal: Brain research20010302

Title: Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys.

Journal: Neurology19970801

Title: Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo.

Journal: Journal of medicinal chemistry19970523

Title: Chronic L-DOPA administration induces dyskinesias in the 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-treated common marmoset (Callithrix Jacchus).

Journal: Movement disorders : official journal of the Movement Disorder Society19951101

Title: Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys.

Journal: The Journal of pharmacology and experimental therapeutics19931001

Title: Kebabian JW, et al. A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets. Eur J Pharmacol. 1992;229(2-3):203-209.

Title: Smith LA, et al. The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration. J Neural Transm (Vienna). 2002;109(2):123-140.

Title: Cooper SJ, et al. The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats. Eur J Pharmacol. 2006;532(3):253-257.

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