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Title: Aldose reductase inhibitors in the treatment of diabetic peripheral neuropathy: a review.
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Title: Inventing and understanding catalytic, enantioselective reactions.
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Title: Ranirestat for the management of diabetic sensorimotor polyneuropathy.
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Title: Improvement of motor nerve conduction velocity in diabetic rats requires normalization of the polyol pathway metabolites flux.
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Title: An improved lanthanum catalyst system for asymmetric amination: toward a practical asymmetric synthesis of AS-3201 (Ranirestat).
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Title: Long-term treatment with ranirestat (AS-3201), a potent aldose reductase inhibitor, suppresses diabetic neuropathy and cataract formation in rats.
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Title: Ranirestat (AS-3201), a potent aldose reductase inhibitor, reduces sorbitol levels and improves motor nerve conduction velocity in streptozotocin-diabetic rats.
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Title: Stability and hydrolysis kinetics of spirosuccinimide type inhibitors of aldose reductase in aqueous solution and retardation of their hydrolysis by the target enzyme.
Journal: Journal of pharmaceutical sciences20080401
Title: Ranirestat as a therapeutic aldose reductase inhibitor for diabetic complications.
Journal: Expert opinion on investigational drugs20080401
Title: Stereospecific recognition of a spirosuccinimide type aldose reductase inhibitor (AS-3201) by plasma proteins: a significant role of specific binding by serum albumin in the improved potency and stability.
Journal: Biochemical pharmacology20060112
Title: Long-term effects of ranirestat (AS-3201) on peripheral nerve function in patients with diabetic sensorimotor polyneuropathy.
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Title: [Progress on the drug therapy for diabetic microangiopathies: aldose reductase inhibitor].
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Title: Aldose reductase inhibition by AS-3201 in sural nerve from patients with diabetic sensorimotor polyneuropathy.
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Title: Uridine diphosphate sugar-selective conjugation of an aldose reductase inhibitor (AS-3201) by UDP-glucuronosyltransferase 2B subfamily in human liver microsomes.
Journal: Biochemical pharmacology20040401
Title: Stereospecific interaction of a novel spirosuccinimide type aldose reductase inhibitor, AS-3201, with aldose reductase.
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