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1523406-39-4,MFCD28411361
Catalog No.:AA00ABQG

1523406-39-4 | SAR405

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$39.00   $27.00
- +
2mg
98+%
in stock  
$58.00   $41.00
- +
5mg
98+%
in stock  
$96.00   $68.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ABQG
Chemical Name:
SAR405
CAS Number:
1523406-39-4
Molecular Formula:
C19H21ClF3N5O2
Molecular Weight:
443.8505
MDL Number:
MFCD28411361
SMILES:
Clc1cncc(c1)CN1c2nc(cc(=O)n2CC[C@H]1C(F)(F)F)N1CCOC[C@H]1C
Properties
Computed Properties
 
Complexity:
731  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.2  

Literature

Title: A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.

Journal: Nature chemical biology 20141201

Title: The study of physician extenders in primary care.

Journal: Health services research 19750101

Title: Ronan B, et al. A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy. Nat Chem Biol. 2014 Dec;10(12):1013-9.

Title: Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6.

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SDS
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Tags:1523406-39-4 Molecular Formula|1523406-39-4 MDL|1523406-39-4 SMILES|1523406-39-4 SAR405
Catalog No.: AA00ABQG
1523406-39-4,MFCD28411361
1523406-39-4 | SAR405
Pack Size： 1mg
Purity： 98+%
in stock
$39.00 $27.00
Pack Size： 2mg
Purity： 98+%
in stock
$58.00 $41.00
Pack Size： 5mg
Purity： 98+%
in stock
$96.00 $68.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00ABQG
Chemical Name: SAR405
CAS Number: 1523406-39-4
Molecular Formula: C19H21ClF3N5O2
Molecular Weight: 443.8505
MDL Number: MFCD28411361
SMILES: Clc1cncc(c1)CN1c2nc(cc(=O)n2CC[C@H]1C(F)(F)F)N1CCOC[C@H]1C
Properties
Complexity: 731  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 30  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.2  
Literature fold

Title: A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.

Journal: Nature chemical biology20141201

Title: The study of physician extenders in primary care.

Journal: Health services research19750101

Title: Ronan B, et al. A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy. Nat Chem Biol. 2014 Dec;10(12):1013-9.

Title: Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6.

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