162641-16-9,MFCD00936179
Catalog No.:AA001T7B

162641-16-9 | Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$55.00   $38.00
- +
5mg
≥98%
in stock  
$172.00   $120.00
- +
10mg
≥98%
in stock  
$209.00   $146.00
- +
50mg
≥98%
in stock  
$782.00   $547.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001T7B
Chemical Name:
Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-
CAS Number:
162641-16-9
Molecular Formula:
C22H27N5O
Molecular Weight:
377.4827
MDL Number:
MFCD00936179
SMILES:
c1ccc(cc1)C(c1ccccc1)OC1CCN(CC1)CCCc1n[nH]nn1
Properties
Computed Properties
 
Complexity:
413  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.8  

Literature

Title: Hematopoetic prostaglandin D synthase: an ESR1-dependent oviductal epithelial cell synthase.

Journal: Endocrinology 20120401

Title: Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2.

Journal: The Journal of pharmacology and experimental therapeutics 20111101

Title: [Hematopoietic prostaglandin D synthase inhibitors for the treatment of duchenne muscular dystrophy].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20111101

Title: Selenium levels affect the IL-4-induced expression of alternative activation markers in murine macrophages.

Journal: The Journal of nutrition 20110901

Title: Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma.

Journal: The Journal of biological chemistry 20110805

Title: Oesophagostomum dentatum: effect of glutathione S-transferase (GST) inhibitors on GST activity and larval development.

Journal: Experimental parasitology 20110401

Title: Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury.

Journal: Glia 20110401

Title: Prostaglandin D(2) synthesis in Oesophagostomum dentatum is mediated by cytosolic glutathione S-transferase.

Journal: Experimental parasitology 20110201

Title: Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment.

Journal: Journal of synchrotron radiation 20110101

Title: Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology.

Journal: Journal of ovarian research 20110101

Title: Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

Journal: Journal of medicinal chemistry 20100812

Title: Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase.

Journal: European journal of medicinal chemistry 20100201

Title: Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice.

Journal: Neuroscience 20090929

Title: Inhibition of prostaglandin D synthase suppresses muscular necrosis.

Journal: The American journal of pathology 20090501

Title: Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.

Journal: Journal of leukocyte biology 20090101

Title: [Structure and function of prostaglandin D synthase].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20080301

Title: Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase.

Journal: The Journal of biological chemistry 20060602

Title: Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways.

Journal: Biochemical pharmacology 20060227

Title: Hematopoietic prostaglandin D synthase.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20030101

Title: Aritake K, et al. Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase. J Biol Chem. 2006 Jun 2;281(22):15277-86. Epub 2006 Mar 17.

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Related Products of 162641-16-9
Tags:162641-16-9 Molecular Formula|162641-16-9 MDL|162641-16-9 SMILES|162641-16-9 Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-
Catalog No.: AA001T7B
162641-16-9,MFCD00936179
162641-16-9 | Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-
Pack Size: 1mg
Purity: ≥98%
in stock
$55.00 $38.00
Pack Size: 5mg
Purity: ≥98%
in stock
$172.00 $120.00
Pack Size: 10mg
Purity: ≥98%
in stock
$209.00 $146.00
Pack Size: 50mg
Purity: ≥98%
in stock
$782.00 $547.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA001T7B
Chemical Name: Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-
CAS Number: 162641-16-9
Molecular Formula: C22H27N5O
Molecular Weight: 377.4827
MDL Number: MFCD00936179
SMILES: c1ccc(cc1)C(c1ccccc1)OC1CCN(CC1)CCCc1n[nH]nn1
Properties
Complexity: 413  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.8  
Literature fold

Title: Hematopoetic prostaglandin D synthase: an ESR1-dependent oviductal epithelial cell synthase.

Journal: Endocrinology20120401

Title: Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2.

Journal: The Journal of pharmacology and experimental therapeutics20111101

Title: [Hematopoietic prostaglandin D synthase inhibitors for the treatment of duchenne muscular dystrophy].

Journal: Brain and nerve = Shinkei kenkyu no shinpo20111101

Title: Selenium levels affect the IL-4-induced expression of alternative activation markers in murine macrophages.

Journal: The Journal of nutrition20110901

Title: Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma.

Journal: The Journal of biological chemistry20110805

Title: Oesophagostomum dentatum: effect of glutathione S-transferase (GST) inhibitors on GST activity and larval development.

Journal: Experimental parasitology20110401

Title: Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury.

Journal: Glia20110401

Title: Prostaglandin D(2) synthesis in Oesophagostomum dentatum is mediated by cytosolic glutathione S-transferase.

Journal: Experimental parasitology20110201

Title: Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment.

Journal: Journal of synchrotron radiation20110101

Title: Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology.

Journal: Journal of ovarian research20110101

Title: Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

Journal: Journal of medicinal chemistry20100812

Title: Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase.

Journal: European journal of medicinal chemistry20100201

Title: Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice.

Journal: Neuroscience20090929

Title: Inhibition of prostaglandin D synthase suppresses muscular necrosis.

Journal: The American journal of pathology20090501

Title: Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.

Journal: Journal of leukocyte biology20090101

Title: [Structure and function of prostaglandin D synthase].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme20080301

Title: Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase.

Journal: The Journal of biological chemistry20060602

Title: Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways.

Journal: Biochemical pharmacology20060227

Title: Hematopoietic prostaglandin D synthase.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20030101

Title: Aritake K, et al. Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase. J Biol Chem. 2006 Jun 2;281(22):15277-86. Epub 2006 Mar 17.

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