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175414-77-4,MFCD13185156
Catalog No.:AA0020WE

175414-77-4 | Voreloxin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$70.00   $49.00
- +
5mg
≥98%
in stock  
$223.00   $156.00
- +
10mg
≥98%
in stock  
$409.00   $286.00
- +
25mg
95%
in stock  
$824.00   $577.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0020WE
Chemical Name:
Voreloxin
CAS Number:
175414-77-4
Molecular Formula:
C18H19N5O4S
Molecular Weight:
401.4396
MDL Number:
MFCD13185156
SMILES:
CN[C@H]1CN(C[C@@H]1OC)c1ccc2c(n1)n(cc(c2=O)C(=O)O)c1nccs1
Properties

Literature

Title: Hotinski AK, et al. Vosaroxin is a novel topoisomerase-II inhibitor with efficacy in relapsed and refractory acute myeloid leukaemia. Expert Opin Pharmacother. 2015 Jun;16(9):1395-402.

Title: Scatena CD, et al. Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo. Cancer Chemother Pharmacol. 2010 Oct;66(5):881-8.

Title: Walsby EJ, et al. The topoisomerase II inhibitor voreloxin causes cell cycle arrest and apoptosis in myeloid leukemia cells and acts in synergy with cytarabine. Haematologica. 2011 Mar;96(3):393-9.

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Tags:175414-77-4 Molecular Formula|175414-77-4 MDL|175414-77-4 SMILES|175414-77-4 Voreloxin
Catalog No.: AA0020WE
175414-77-4,MFCD13185156
175414-77-4 | Voreloxin
Pack Size： 1mg
Purity： ≥98%
in stock
$70.00 $49.00
Pack Size： 5mg
Purity： ≥98%
in stock
$223.00 $156.00
Pack Size： 10mg
Purity： ≥98%
in stock
$409.00 $286.00
Pack Size： 25mg
Purity： 95%
in stock
$824.00 $577.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA0020WE
Chemical Name: Voreloxin
CAS Number: 175414-77-4
Molecular Formula: C18H19N5O4S
Molecular Weight: 401.4396
MDL Number: MFCD13185156
SMILES: CN[C@H]1CN(C[C@@H]1OC)c1ccc2c(n1)n(cc(c2=O)C(=O)O)c1nccs1
Properties
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