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1782235-14-6,MFCD29079432
Catalog No.:AA00ABP9

1782235-14-6 | CHIR 99021 trihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
1 week  
$87.00   $61.00
- +
250mg
98%
1 week  
$198.00   $139.00
- +
1g
98%
1 week  
$594.00   $416.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ABP9
Chemical Name:
CHIR 99021 trihydrochloride
CAS Number:
1782235-14-6
Molecular Formula:
C22H21Cl5N8
Molecular Weight:
574.7207
MDL Number:
MFCD29079432
SMILES:
N#Cc1ccc(nc1)NCCNc1ncc(c(n1)c1ccc(cc1Cl)Cl)c1ncc([nH]1)C.Cl.Cl.Cl
Properties
Computed Properties
 
Complexity:
645  
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Ring DB, et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.

Title: Naujok O, et al. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors.BMC Res Notes. 2014 Apr 29;7:273.

Title: Ye S, et al. Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PLoS One. 2012;7(4):e35892.

Title: Bennett CN, et al. Regulation of Wnt signaling during adipogenesis. J Biol Chem. 2002 Aug 23;277(34):30998-1004.

Title: Wang X, et al. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Sci Rep. 2015 Apr 10;5:8566.

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SDS
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Tags:1782235-14-6 Molecular Formula|1782235-14-6 MDL|1782235-14-6 SMILES|1782235-14-6 CHIR 99021 trihydrochloride
Catalog No.: AA00ABP9
1782235-14-6,MFCD29079432
1782235-14-6 | CHIR 99021 trihydrochloride
Pack Size： 100mg
Purity： 98%
1 week
$87.00 $61.00
Pack Size： 250mg
Purity： 98%
1 week
$198.00 $139.00
Pack Size： 1g
Purity： 98%
1 week
$594.00 $416.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00ABP9
Chemical Name: CHIR 99021 trihydrochloride
CAS Number: 1782235-14-6
Molecular Formula: C22H21Cl5N8
Molecular Weight: 574.7207
MDL Number: MFCD29079432
SMILES: N#Cc1ccc(nc1)NCCNc1ncc(c(n1)c1ccc(cc1Cl)Cl)c1ncc([nH]1)C.Cl.Cl.Cl
Properties
Complexity: 645  
Covalently-Bonded Unit Count: 4  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 35  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
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