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1797989-42-4,MFCD30489757
Catalog No.:AA00ABP8

1797989-42-4 | CHIR-99021 (monohydrochloride)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$8.00   $6.00
- +
2mg
98%
in stock  
$12.00   $8.00
- +
5mg
98%
in stock  
$20.00   $14.00
- +
10mg
98%
in stock  
$29.00   $20.00
- +
50mg
98%
in stock  
$82.00   $57.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ABP8
Chemical Name:
CHIR-99021 (monohydrochloride)
CAS Number:
1797989-42-4
Molecular Formula:
C22H19Cl3N8
Molecular Weight:
501.7989
MDL Number:
MFCD30489757
SMILES:
N#Cc1ccc(nc1)NCCNc1ncc(c(n1)c1ccc(cc1Cl)Cl)c1ncc([nH]1)C.Cl
Properties
Computed Properties
 
Complexity:
645  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Ring DB, et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.

Title: Naujok O, et al. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors.BMC Res Notes. 2014 Apr 29;7:273.

Title: Ye S, et al. Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PLoS One. 2012;7(4):e35892.

Title: Bennett CN, et al. Regulation of Wnt signaling during adipogenesis. J Biol Chem. 2002 Aug 23;277(34):30998-1004.

Title: Wang X, et al. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Sci Rep. 2015 Apr 10;5:8566.

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SDS
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Tags:1797989-42-4 Molecular Formula|1797989-42-4 MDL|1797989-42-4 SMILES|1797989-42-4 CHIR-99021 (monohydrochloride)
Catalog No.: AA00ABP8
1797989-42-4,MFCD30489757
1797989-42-4 | CHIR-99021 (monohydrochloride)
Pack Size： 1mg
Purity： 98%
in stock
$8.00 $6.00
Pack Size： 2mg
Purity： 98%
in stock
$12.00 $8.00
Pack Size： 5mg
Purity： 98%
in stock
$20.00 $14.00
Pack Size： 10mg
Purity： 98%
in stock
$29.00 $20.00
Pack Size： 50mg
Purity： 98%
in stock
$82.00 $57.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00ABP8
Chemical Name: CHIR-99021 (monohydrochloride)
CAS Number: 1797989-42-4
Molecular Formula: C22H19Cl3N8
Molecular Weight: 501.7989
MDL Number: MFCD30489757
SMILES: N#Cc1ccc(nc1)NCCNc1ncc(c(n1)c1ccc(cc1Cl)Cl)c1ncc([nH]1)C.Cl
Properties
Complexity: 645  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 33  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
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