18551-00-3,MFCD01315211
Catalog No.:AA00IQO0

18551-00-3 | (2E)-3-(Furan-2-yl)-1-(pyridin-2-yl)prop-2-en-1-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
>90%
1 week  
$299.00   $209.00
- +
5mg
>90%
1 week  
$319.00   $223.00
- +
10mg
>90%
1 week  
$358.00   $250.00
- +
500mg
>90%
1 week  
$1,087.00   $761.00
- +
1g
>90%
1 week  
$1,960.00   $1,372.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00IQO0
Chemical Name:
(2E)-3-(Furan-2-yl)-1-(pyridin-2-yl)prop-2-en-1-one
CAS Number:
18551-00-3
Molecular Formula:
C12H9NO2
Molecular Weight:
199.2054
MDL Number:
MFCD01315211
SMILES:
O=C(c1ccccn1)/C=C/c1ccco1
Properties
Computed Properties
 
Complexity:
250  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
1  
XLogP3:
2.1  

Literature

Title: The anti-angiogenic effects of 1-furan-2-yl-3-pyridin-2-yl-propenone are mediated through the suppression of both VEGF production and VEGF-induced signaling.

Journal: Vascular pharmacology 20090101

Title: Activation of the Nrf2-antioxidant system by a novel cyclooxygenase-2 inhibitor furan-2-yl-3-pyridin-2-yl-propenone: implication in anti-inflammatory function by Nrf2 activator.

Journal: The Journal of pharmacy and pharmacology 20080701

Title: In vitro characterization of the enzymes involved in the metabolism of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound.

Journal: Archives of pharmacal research 20080601

Title: Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity.

Journal: Toxicology and applied pharmacology 20080501

Title: 1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.

Journal: European journal of pharmacology 20070719

Title: The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of warfarin.

Journal: Archives of pharmacal research 20070701

Title: Metabolism of FPP-3, an anti-inflammatory propenone compound, in rat by liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin 20070501

Title: Identification of 1-furan-2-yl-3-pyridin-2-yl-propenone, an antiinflammatory agent, and its metabolites in rat liver subcellular fractions.

Journal: Archives of pharmacal research 20061101

Title: Determination of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound, by high performance liquid chromatography with ultraviolet spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606

Title: The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of theophylline.

Journal: Biological & pharmaceutical bulletin 20060601

Title: Potent analgesic and anti-inflammatory activities of 1-furan-2-yl-3-pyridin-2-yl-propenone with gastric ulcer sparing effect.

Journal: Biological & pharmaceutical bulletin 20060201

Title: Inhibition of nitric oxide and tumor necrosis factor-alpha (TNF-alpha) production by propenone compound through blockade of nuclear factor (NF)-kappa B activation in cultured murine macrophages.

Journal: Biological & pharmaceutical bulletin 20040501

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Related Products of 18551-00-3
Tags:18551-00-3 Molecular Formula|18551-00-3 MDL|18551-00-3 SMILES|18551-00-3 (2E)-3-(Furan-2-yl)-1-(pyridin-2-yl)prop-2-en-1-one
Catalog No.: AA00IQO0
18551-00-3,MFCD01315211
18551-00-3 | (2E)-3-(Furan-2-yl)-1-(pyridin-2-yl)prop-2-en-1-one
Pack Size: 1mg
Purity: >90%
1 week
$299.00 $209.00
Pack Size: 5mg
Purity: >90%
1 week
$319.00 $223.00
Pack Size: 10mg
Purity: >90%
1 week
$358.00 $250.00
Pack Size: 500mg
Purity: >90%
1 week
$1,087.00 $761.00
Pack Size: 1g
Purity: >90%
1 week
$1,960.00 $1,372.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00IQO0
Chemical Name: (2E)-3-(Furan-2-yl)-1-(pyridin-2-yl)prop-2-en-1-one
CAS Number: 18551-00-3
Molecular Formula: C12H9NO2
Molecular Weight: 199.2054
MDL Number: MFCD01315211
SMILES: O=C(c1ccccn1)/C=C/c1ccco1
Properties
Complexity: 250  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 15  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 1  
XLogP3: 2.1  
Literature fold

Title: The anti-angiogenic effects of 1-furan-2-yl-3-pyridin-2-yl-propenone are mediated through the suppression of both VEGF production and VEGF-induced signaling.

Journal: Vascular pharmacology20090101

Title: Activation of the Nrf2-antioxidant system by a novel cyclooxygenase-2 inhibitor furan-2-yl-3-pyridin-2-yl-propenone: implication in anti-inflammatory function by Nrf2 activator.

Journal: The Journal of pharmacy and pharmacology20080701

Title: In vitro characterization of the enzymes involved in the metabolism of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound.

Journal: Archives of pharmacal research20080601

Title: Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity.

Journal: Toxicology and applied pharmacology20080501

Title: 1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.

Journal: European journal of pharmacology20070719

Title: The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of warfarin.

Journal: Archives of pharmacal research20070701

Title: Metabolism of FPP-3, an anti-inflammatory propenone compound, in rat by liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin20070501

Title: Identification of 1-furan-2-yl-3-pyridin-2-yl-propenone, an antiinflammatory agent, and its metabolites in rat liver subcellular fractions.

Journal: Archives of pharmacal research20061101

Title: Determination of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound, by high performance liquid chromatography with ultraviolet spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20060606

Title: The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of theophylline.

Journal: Biological & pharmaceutical bulletin20060601

Title: Potent analgesic and anti-inflammatory activities of 1-furan-2-yl-3-pyridin-2-yl-propenone with gastric ulcer sparing effect.

Journal: Biological & pharmaceutical bulletin20060201

Title: Inhibition of nitric oxide and tumor necrosis factor-alpha (TNF-alpha) production by propenone compound through blockade of nuclear factor (NF)-kappa B activation in cultured murine macrophages.

Journal: Biological & pharmaceutical bulletin20040501

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