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190508-50-0,MFCD11040941
Catalog No.:AA00ASUK

190508-50-0 | AT 1015

This product is typically in stock,please click "Inquire" below or
contact us at [email protected] for pricing and availability information.
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ASUK
Chemical Name:
AT 1015
CAS Number:
190508-50-0
Molecular Formula:
C29H34ClN3O2
Molecular Weight:
492.0522
MDL Number:
MFCD11040941
SMILES:
O=CN1CCC(CC1)C(=O)NCCN1CCC(=C2c3ccccc3C=Cc3c2cccc3)CC1.Cl
Properties
Computed Properties
 
Complexity:
744  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: AT-1015, a novel serotonin2A receptor antagonist, improves resaturation of exercised ischemic muscle in hypercholesterolemic rabbits.

Journal: Journal of vascular surgery 20040301

Title: Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy.

Journal: Vascular medicine (London, England) 20040201

Title: Insurmountable antagonism of AT-1015, a 5-HT2 antagonist, on serotonin-induced endothelium-dependent relaxation in porcine coronary artery.

Journal: The Journal of pharmacy and pharmacology 20030601

Title: AT-1015, a newly synthesized 5-HT2 receptor antagonist, dissociates slowly from the 5-HT2 receptor sites in rabbit cerebral cortex membrane.

Journal: The Journal of pharmacy and pharmacology 20020801

Title: Antithrombotic activity of AT-1015, a potent 5-HT(2A) receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time.

Journal: European journal of pharmacology 20011221

Title: Assessment of affinity and dissociation ability of a newly synthesized 5-HT2 antagonist, AT-1015: comparison with other 5-HT2 antagonists.

Journal: Japanese journal of pharmacology 20011101

Title: Binding affinity of a newly synthesized 5-HT2 antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-piperidino]ethyl]-1-formyl-4-piperidinecarboxamide monohydrochloride monohydrate), in the rabbit platelet membrane.

Journal: Biological & pharmaceutical bulletin 20011001

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SDS
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Tags:190508-50-0 Molecular Formula|190508-50-0 MDL|190508-50-0 SMILES|190508-50-0 AT 1015
Catalog No.: AA00ASUK
190508-50-0,MFCD11040941
190508-50-0 | AT 1015
This product is typically in stock,please click "Inquire" below or contact us at [email protected]for pricing and availability information.
Inquire
Technical Information
Catalog Number: AA00ASUK
Chemical Name: AT 1015
CAS Number: 190508-50-0
Molecular Formula: C29H34ClN3O2
Molecular Weight: 492.0522
MDL Number: MFCD11040941
SMILES: O=CN1CCC(CC1)C(=O)NCCN1CCC(=C2c3ccccc3C=Cc3c2cccc3)CC1.Cl
Properties
Complexity: 744  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 35  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: AT-1015, a novel serotonin2A receptor antagonist, improves resaturation of exercised ischemic muscle in hypercholesterolemic rabbits.

Journal: Journal of vascular surgery20040301

Title: Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy.

Journal: Vascular medicine (London, England)20040201

Title: Insurmountable antagonism of AT-1015, a 5-HT2 antagonist, on serotonin-induced endothelium-dependent relaxation in porcine coronary artery.

Journal: The Journal of pharmacy and pharmacology20030601

Title: AT-1015, a newly synthesized 5-HT2 receptor antagonist, dissociates slowly from the 5-HT2 receptor sites in rabbit cerebral cortex membrane.

Journal: The Journal of pharmacy and pharmacology20020801

Title: Antithrombotic activity of AT-1015, a potent 5-HT(2A) receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time.

Journal: European journal of pharmacology20011221

Title: Assessment of affinity and dissociation ability of a newly synthesized 5-HT2 antagonist, AT-1015: comparison with other 5-HT2 antagonists.

Journal: Japanese journal of pharmacology20011101

Title: Binding affinity of a newly synthesized 5-HT2 antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-piperidino]ethyl]-1-formyl-4-piperidinecarboxamide monohydrochloride monohydrate), in the rabbit platelet membrane.

Journal: Biological & pharmaceutical bulletin20011001

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957-66-4
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1428352-71-9
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879936-95-5
879936-95-5
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1698597-68-0
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Submit
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