191611-89-9,MFCD04113118
Catalog No.:AA00ASV5

191611-89-9 | SIB 1553A hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$166.00   $116.00
- +
10mg
≥98%
in stock  
$262.00   $183.00
- +
50mg
≥98%
in stock  
$1,035.00   $724.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ASV5
Chemical Name:
SIB 1553A hydrochloride
CAS Number:
191611-89-9
Molecular Formula:
C13H20ClNOS
Molecular Weight:
273.8220
MDL Number:
MFCD04113118
SMILES:
CN1CCCC1CCSc1ccc(cc1)O.Cl
Properties
Computed Properties
 
Complexity:
204  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Interaction between nicotinic and dopaminergic therapies on cognition in a chronic Parkinson model.

Journal: Brain research 20090325

Title: Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for beta4 selective subtype nicotinic acetylcholine receptor.

Journal: Nuclear medicine and biology 20080401

Title: Effects of nicotinic therapies on attention and executive functions in chronic low-dose MPTP-treated monkeys.

Journal: The European journal of neuroscience 20061001

Title: In vivo pharmacological characterization of (+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies.

Journal: Brain research 20031003

Title: In vitro pharmacological characterization of (+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand.

Journal: Brain research 20030815

Title: Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701

Title: The subtype-selective nicotinic acetylcholine receptor agonist SIB-1553A improves both attention and memory components of a spatial working memory task in chronic low dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: Effects of (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a selective ligand for nicotinic acetylcholine receptors, in tests of visual attention and distractibility in rats and monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20020401

Title: A study of the nicotinic agonist SIB-1553A on locomotion and attention as measured by the five-choice serial reaction time task.

Journal: Pharmacology, biochemistry, and behavior 20011201

Title: SIB-1553A, (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride, a subtype-selective ligand for nicotinic acetylcholine receptors with putative cognitive-enhancing properties: effects on working and reference memory performances in aged rodents and nonhuman primates.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Vernier JM, et al. 4-[-(1-Methyl-2-pyrrolidinyl)ethylthiophenol hydrochloride (SIB-1553A): a novel cognitive enhancer with selectivity for neuronal nicotinic acetylcholine receptors. J Med Chem. 1999 May 20;42(10):1684-6.

Title: Rao TS, et al. In vitro pharmacological characterization of (+/-)-4--(1-methyl-2-pyrrolidinyl)ethylthiophenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand. Brain Res. 2003 Aug 15;981(1-2):85-98.

Title: Rao TS, et al. In vivo pharmacological characterization of (+/-)-4--(1-methyl-2-pyrrolidinyl)ethylthiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies. Brain Res. 2003 Oct 3;986(1-2):71-81.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 191611-89-9
Tags:191611-89-9 Molecular Formula|191611-89-9 MDL|191611-89-9 SMILES|191611-89-9 SIB 1553A hydrochloride
Catalog No.: AA00ASV5
191611-89-9,MFCD04113118
191611-89-9 | SIB 1553A hydrochloride
Pack Size: 1mg
Purity: ≥98%
in stock
$46.00 $32.00
Pack Size: 5mg
Purity: ≥98%
in stock
$166.00 $116.00
Pack Size: 10mg
Purity: ≥98%
in stock
$262.00 $183.00
Pack Size: 50mg
Purity: ≥98%
in stock
$1,035.00 $724.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00ASV5
Chemical Name: SIB 1553A hydrochloride
CAS Number: 191611-89-9
Molecular Formula: C13H20ClNOS
Molecular Weight: 273.8220
MDL Number: MFCD04113118
SMILES: CN1CCCC1CCSc1ccc(cc1)O.Cl
Properties
Complexity: 204  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 17  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Interaction between nicotinic and dopaminergic therapies on cognition in a chronic Parkinson model.

Journal: Brain research20090325

Title: Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for beta4 selective subtype nicotinic acetylcholine receptor.

Journal: Nuclear medicine and biology20080401

Title: Effects of nicotinic therapies on attention and executive functions in chronic low-dose MPTP-treated monkeys.

Journal: The European journal of neuroscience20061001

Title: In vivo pharmacological characterization of (+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies.

Journal: Brain research20031003

Title: In vitro pharmacological characterization of (+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand.

Journal: Brain research20030815

Title: Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20030701

Title: The subtype-selective nicotinic acetylcholine receptor agonist SIB-1553A improves both attention and memory components of a spatial working memory task in chronic low dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.

Journal: The Journal of pharmacology and experimental therapeutics20030701

Title: Effects of (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a selective ligand for nicotinic acetylcholine receptors, in tests of visual attention and distractibility in rats and monkeys.

Journal: The Journal of pharmacology and experimental therapeutics20020401

Title: A study of the nicotinic agonist SIB-1553A on locomotion and attention as measured by the five-choice serial reaction time task.

Journal: Pharmacology, biochemistry, and behavior20011201

Title: SIB-1553A, (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride, a subtype-selective ligand for nicotinic acetylcholine receptors with putative cognitive-enhancing properties: effects on working and reference memory performances in aged rodents and nonhuman primates.

Journal: The Journal of pharmacology and experimental therapeutics20011001

Title: Vernier JM, et al. 4-[-(1-Methyl-2-pyrrolidinyl)ethylthiophenol hydrochloride (SIB-1553A): a novel cognitive enhancer with selectivity for neuronal nicotinic acetylcholine receptors. J Med Chem. 1999 May 20;42(10):1684-6.

Title: Rao TS, et al. In vitro pharmacological characterization of (+/-)-4--(1-methyl-2-pyrrolidinyl)ethylthiophenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand. Brain Res. 2003 Aug 15;981(1-2):85-98.

Title: Rao TS, et al. In vivo pharmacological characterization of (+/-)-4--(1-methyl-2-pyrrolidinyl)ethylthiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies. Brain Res. 2003 Oct 3;986(1-2):71-81.

Building Blocks More >
148672-15-5
148672-15-5
2'-METHYL-4'-(5-METHYL-[1,3,4]OXADIAZOL-2-YL)-BIPHENYL-4-CARBOXYLIC ACID [4-METHOXY-3-(4-METHYL-PIPERAZIN-1-YL)-PHENYL]-AMIDE
AA00ATBS | MFCD00919101
168749-62-0
168749-62-0
Benzenemethanol, -alpha-,2,4-trimethyl-, (-alpha-S)- (9CI)
AA00AUKM | MFCD09863727
156695-44-2
156695-44-2
2-(5-Bromo-1h-indol-3-yl)-2-oxoacetic acid
AA00AX0S | MFCD09909340
15299-77-1
15299-77-1
13,14-Dihydro-2',14β-dihydroxy-4'',5''-dimethoxylythran-12-one
AA00AZQY
19115-30-1
19115-30-1
1'-hydroxy-2',3'-dehydroestragole
AA00B3AH | MFCD01732756
15286-98-3
15286-98-3
4-Acrylamidobenzoic acid
AA00B4YF | MFCD00584317
151389-59-2
151389-59-2
N1-(2-BROMOETHYL)-4-CHLOROBENZENE-1-SULFONAMIDE, TECH
AA00B89G | MFCD00828740
185692-04-0
185692-04-0
tert-Butyl methyl(morpholin-2-ylmethyl)carbamate
AA00BATB | MFCD14635766
26893-68-5
26893-68-5
6-Nitropyridine-2-carboxylic acid
AA00BBK0 | MFCD04114205
242138-07-4
242138-07-4
OMALIZUMAB
AA00BBQQ
Submit
© 2017 AA BLOCKS, INC. All rights reserved.