Name: Name:7H-Dibenzo[c,g]carbazole
Brand: AABLOCKS
SKU: AA003NCN
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA003NCN

Chemical Name: 7H-Dibenzo[c,g]carbazole

CAS Number: 194-59-2

Molecular Formula: C20H13N

Molecular Weight: 267.3239

MDL Number: MFCD00215941

SMILES: c1ccc2c(c1)ccc1c2c2c([nH]1)ccc1c2cccc1

NSC Number: 87519

UN Number: 2811

Properties

BP: 544.1°C at 760 mmHg

Form: Solid

MP: 152-154°C

Refractive Index: 1.8610 (estimate)

Storage: Keep in dry area;2-8℃;

Complexity: 355

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 21

Hydrogen Bond Acceptor Count: 0

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 5.9

Literature fold

Title: Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation.

Journal: Toxicology and applied pharmacology20130815

Title: Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.

Journal: Report on carcinogens : carcinogen profiles20110101

Title: 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.

Journal: Carcinogenesis20070601

Title: Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies.

Journal: Toxicology letters20060410

Title: DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes.

Journal: Environmental and molecular mutagenesis20040101

Title: A metabolic activation mechanism of 7H-dibenzo[c,g]carbazole via o-quinone. Part 2: covalent adducts of 7H-dibenzo[c,g]carbazole-3,4-dione with nucleic acid bases and nucleosides.

Journal: Chemical research in toxicology20020701

Title: Mutagenicity of 7H-dibenzo[c,g]carbazole and its tissue specific derivatives in genetically engineered Chinese hamster V79 cell lines stably expressing cytochrome P450.

Journal: Mutation research20020527

Title: Comparison of Ha-ras mutational spectra of N-methyldibenzo[c,g]carbazole and 7H-dibenzo[c,g]carbazole-induced mouse skin tumors.

Journal: Molecular carcinogenesis20011001

Title: The effects of a binary mixture of benzo(a)pyrene and 7H-dibenzo(c,g)carbazole on lung tumors and K-ras oncogene mutations in strain A/J mice.

Journal: Experimental lung research20010101

Title: Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytes.

Journal: Environmental and molecular mutagenesis19950101