Name: Name:2-Oxo-1,2-dihydro-quinoline-3-carboxylic acid
Brand: AABLOCKS
SKU: AA002CL7
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA002CL7

Chemical Name: 2-Oxo-1,2-dihydro-quinoline-3-carboxylic acid

CAS Number: 2003-79-4

Molecular Formula: C10H7NO3

Molecular Weight: 189.1675

MDL Number: MFCD01550054

SMILES: OC(=O)c1cc2ccccc2[nH]c1=O

NSC Number: 329342

Properties

Complexity: 309

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 14

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.6

Literature fold

Title: 6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.

Journal: Bioorganic & medicinal chemistry letters20110115

Title: Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets.

Journal: Scientia pharmaceutica20110101

Title: RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets.

Journal: Indian journal of pharmaceutical sciences20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: The mechanism of metal cation binding in two nalidixate calixarene conjugates. A langmuir film and molecular modeling study.

Journal: The journal of physical chemistry. B20100819

Title: N-heterocyclic derived M1 positive allosteric modulators.

Journal: Bioorganic & medicinal chemistry letters20100215

Title: Pyridine containing M(1) positive allosteric modulators with reduced plasma protein binding.

Journal: Bioorganic & medicinal chemistry letters20100115

Title: Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulators.

Journal: Bioorganic & medicinal chemistry letters20100115

Title: Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.

Journal: PloS one20100101

Title: Synthesis, characterization, antibacterial and anti-inflammatory activities of enoxacin metal complexes.

Journal: Bioinorganic chemistry and applications20090101

Title: In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin.

Journal: Journal of veterinary science20061201

Title: Sorption of veterinary pharmaceuticals in soils: a review.

Journal: Environmental science & technology20010901

Title: Evaluation of cardiac subacute toxicity of ciprofloxacin in rats using serum biochemical parameters.

Journal: Arzneimittel-Forschung20010101

2003-79-4 | 2-Oxo-1,2-dihydro-quinoline-3-carboxylic acid