Name: Name:4-(4-methylcyclohexyl)-4-oxobutanoic acid
Brand: AABLOCKS
SKU: AA01C3VK
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01C3VK

Chemical Name: 4-(4-methylcyclohexyl)-4-oxobutanoic acid

CAS Number: 220203-23-6

Molecular Formula: C11H18O3

Molecular Weight: 198.2588

MDL Number: MFCD21296520

SMILES: CC1CCC(CC1)C(=O)CCC(=O)O

Properties

Complexity: 215

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 14

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.7

Literature fold

Title: Daily inhibition of postprandial hyperglycaemia with JTT-608, a novel oral antidiabetic agent, ameliorates pancreatic function in neonatally streptozotocin-treated rats.

Journal: Diabetes, obesity & metabolism20050901

Title: Antidiabetic effect of chronic administration of JTT-608, a new hypoglycemic agent, in diabetic Goto-Kakizaki rats.

Journal: European journal of pharmacology20030822

Title: A novel enhancer of insulinotrophic action by high glucose (JTT-608) stimulates insulin secretion from pancreatic beta-cells via a new cellular mechanism.

Journal: The Journal of pharmacology and experimental therapeutics20010601

Title: A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate cyclase-activating polypeptide.

Journal: The Journal of pharmacology and experimental therapeutics20010101

220203-23-6 | 4-(4-methylcyclohexyl)-4-oxobutanoic acid