Name: Name:glisoxepide
Brand: AABLOCKS
SKU: AA00C2VA
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00C2VA

Chemical Name: glisoxepide

CAS Number: 25046-79-1

Molecular Formula: C20H27N5O5S

Molecular Weight: 449.5239

MDL Number: MFCD00865498

SMILES: Cc1onc(c1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NN1CCCCCC1

Properties

Complexity: 697

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 31

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 7

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.9

Literature fold

Title: Simultaneous identification and validated quantification of 11 oral hypoglycaemic drugs in plasma by electrospray ionisation liquid chromatography-mass spectrometry.

Journal: Analytical and bioanalytical chemistry20110401

Title: Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection.

Journal: The Journal of pharmacology and experimental therapeutics20060101

Title: Identification and quantification of 8 sulfonylureas with clinical toxicology interest by liquid chromatography-ion-trap tandem mass spectrometry and library searching.

Journal: Clinical chemistry20050901

Title: Antidiabetic sulphonylureas activate mitochondrial permeability transition in rat skeletal muscle.

Journal: British journal of pharmacology20050701

Title: Screening, library-assisted identification and validated quantification of oral antidiabetics of the sulfonylurea-type in plasma by atmospheric pressure chemical ionization liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20020615

Title: Sato T, et al. Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. J Pharmacol Exp Ther. 2006 Jan;316(1):182-8. Epub 2005 Sep 20.

Title: Selvaag E. Photohemolytic potency of oral antidiabetic drugs in vitro: effects of antioxidants and a nitrogen atmosphere. Photodermatol Photoimmunol Photomed. 1996 Aug;12(4):166-70.

Title: Fückel D, et al. Interaction of sulfonylureas with the transport of bile acids into hepatocytes. Eur J Pharmacol. 1992 Mar 31;213(3):393-404.

25046-79-1 | glisoxepide