Name: Name:Imidazo[1,2-a]pyrimidine
Brand: AABLOCKS
SKU: AA003QWT
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA003QWT

Chemical Name: Imidazo[1,2-a]pyrimidine

CAS Number: 274-95-3

Molecular Formula: C6H5N3

Molecular Weight: 119.1240

MDL Number: MFCD06245377

SMILES: c1ccn2c(n1)ncc2

Properties

Form: Solid

MP: 129-130°C

Storage: Keep in dry area;Room Temperature;

Complexity: 105

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 9

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.1

62:

Literature fold

Title: Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds.

Journal: Bioorganic & medicinal chemistry20120401

Title: Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes.

Journal: Psychopharmacology20120201

Title: Systematic structure modifications of imidazo[1,2-a]pyrimidine to reduce metabolism mediated by aldehyde oxidase (AO).

Journal: Journal of medicinal chemistry20111110

Title: Structure-activity relationship of 4(5)-aryl-2-amino-1H-imidazoles, N1-substituted 2-aminoimidazoles and imidazo[1,2-a]pyrimidinium salts as inhibitors of biofilm formation by Salmonella typhimurium and Pseudomonas aeruginosa.

Journal: Journal of medicinal chemistry20110127

Title: Post Groebke-Blackburn multicomponent protocol: synthesis of new polyfunctional imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives as potential antimicrobial agents.

Journal: European journal of medicinal chemistry20101201

Title: 5-HT1A receptor blockade reverses GABA(A) receptor alpha3 subunit-mediated anxiolytic effects on stress-induced hyperthermia.

Journal: Psychopharmacology20100801

Title: Efficient one-pot, two-step, microwave-assisted procedure for the synthesis of polysubstituted 2-aminoimidazoles.

Journal: Organic letters20061207

Title: 8-Fluoroimidazo[1,2-a]pyridine: synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABA A receptor.

Journal: Bioorganic & medicinal chemistry letters20060315

Title: Palladium-catalyzed regioselective arylation of imidazo[1,2-a]pyrimidine.

Journal: Organic letters20031211

Title: Effect of imidazo[1,2-a]pyrimidine derivatives on leukocyte function.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20010601

274-95-3 | Imidazo[1,2-a]pyrimidine