301326-22-7,MFCD00377884
Catalog No.:AA00BE8F

301326-22-7 | 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$77.00   $54.00
- +
25mg
≥95%
in stock  
$315.00   $220.00
- +
50mg
in stock  
$558.00   $390.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00BE8F
Chemical Name:
1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
CAS Number:
301326-22-7
Molecular Formula:
C19H19N5O
Molecular Weight:
333.3871
MDL Number:
MFCD00377884
SMILES:
Cc1cc(ccc1NC(=O)c1ccnn1C)N=Nc1ccccc1C
Properties
Computed Properties
 
Complexity:
482  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.9  

Literature

Title: Lymphocyte-Specific Protein Tyrosine Kinase (LCK) is Involved in the Aryl Hydrocarbon Receptor-Mediated Impairment of Immunoglobulin Secretion in Human Primary B Cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20181001

Title: In vitro toxicity and in silico docking analysis of two novel selective AH-receptor modulators.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20181001

Title: Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180901

Title: Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.

Journal: Toxicology letters 20180801

Title: Relative effective potencies of dioxin-like compounds in rodent and human lung cell models.

Journal: Toxicology 20180701

Title: Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells.

Journal: Toxicology letters 20180601

Title: Suppression of the IgM Response by Aryl Hydrocarbon Receptor Activation in Human Primary B Cells Involves Impairment of Immunoglobulin Secretory Processes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180501

Title: Diesel exhaust particulate associated chemicals attenuate expression of CXCL10 in human primary bronchial epithelial cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: Actein alleviates 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated cellular dysfunction in osteoblastic MC3T3-E1 cells.

Journal: Environmental toxicology 20171201

Title: Editor's Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20171101

Title: Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells.

Journal: Archives of toxicology 20170101

Title: SHP-1 is directly activated by the aryl hydrocarbon receptor and regulates BCL-6 in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Journal: Toxicology and applied pharmacology 20161101

Title: Activation of aryl hydrocarbon receptor reduces carbendazim-induced cell death.

Journal: Toxicology and applied pharmacology 20160901

Title: Aryl hydrocarbon receptor-ligand axis mediates pulmonary fibroblast migration and differentiation through increased arachidonic acid metabolism.

Journal: Toxicology 20160831

Title: Benzo[ghi]perylene activates the AHR pathway to exert biological effects on the NL-20 human bronchial cell line.

Journal: Toxicology letters 20160810

Title: Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Journal: Toxicology 20160810

Title: Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1.

Journal: Toxicology and applied pharmacology 20160601

Title: TCDD promoted EMT of hFPECs via AhR, which involved the activation of EGFR/ERK signaling.

Journal: Toxicology and applied pharmacology 20160501

Title: Crosstalk between AhR and wnt/β-catenin signal pathways in the cardiac developmental toxicity of PM2.5 in zebrafish embryos.

Journal: Toxicology 20160429

Title: Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.

Journal: Chemical research in toxicology 20160119

Title: PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160101

Title: Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells.

Journal: Toxicology and applied pharmacology 20160101

Title: Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator.

Journal: The Journal of toxicological sciences 20160101

Title: Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.

Journal: Archives of toxicology 20151201

Title: Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells.

Journal: The Journal of toxicological sciences 20151201

Title: Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes.

Journal: Toxicology 20151104

Title: Cytokine responses induced by diesel exhaust particles are suppressed by PAR-2 silencing and antioxidant treatment, and driven by polar and non-polar soluble constituents.

Journal: Toxicology letters 20151014

Title: Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151001

Title: Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.

Journal: Chemical research in toxicology 20150817

Title: Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.

Journal: Chemical research in toxicology 20150518

Title: Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital.

Journal: Toxicology 20150203

Title: PCB126 inhibits adipogenesis of human preadipocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150201

Title: Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation.

Journal: Toxicology and applied pharmacology 20141101

Title: The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway.

Journal: Toxicology and applied pharmacology 20141101

Title: The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines.

Journal: Molecular carcinogenesis 20141001

Title: Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line.

Journal: International journal of environmental research and public health 20140901

Title: Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesion molecule-1 (ICAM-1).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140701

Title: A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140401

Title: Differentiation of human placental BeWo cells by the environmental contaminant benzo(a)pyrene.

Journal: Chemico-biological interactions 20140305

Title: Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140301

Title: The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development.

Journal: PloS one 20140101

Title: Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells.

Journal: Toxicology letters 20131023

Title: Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130501

Title: AhR-mediated effects of dioxin on neuronal acetylcholinesterase expression in vitro.

Journal: Environmental health perspectives 20130501

Title: AhR-mediated changes in global gene expression in rat liver progenitor cells.

Journal: Archives of toxicology 20130401

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130301

Title: Cyprodinil as an activator of aryl hydrocarbon receptor.

Journal: Toxicology 20130208

Title: Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis.

Journal: Environmental health perspectives 20130101

Title: Cigarette smoke condensate induces aryl hydrocarbon receptor-dependent changes in gene expression in spermatocytes.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20121201

Title: The androgenic anabolic steroid tetrahydrogestrinone produces dioxin-like effects via the aryl hydrocarbon receptor.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20121001

Title: Cardiosulfa induces heart deformation in zebrafish through the AhR-mediated, CYP1A-independent pathway.

Journal: Chembiochem : a European journal of chemical biology 20120709

Title: FOXA1 is essential for aryl hydrocarbon receptor-dependent regulation of cyclin G2.

Journal: Molecular cancer research : MCR 20120501

Title: Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells.

Journal: Biomedical research (Tokyo, Japan) 20120401

Title: Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor.

Journal: Molecular pharmacology 20120101

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin's suppression of 1-nitropyrene-induced p53 expression is mediated by cytochrome P450 1A1.

Journal: Chemical research in toxicology 20111219

Title: The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachloro-dibenzo-p-dioxin (TCDD) alters early embryonic development in a rat IVF exposure model.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20111101

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription.

Journal: American journal of respiratory cell and molecular biology 20110801

Title: Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells.

Journal: Toxicology 20110711

Title: Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism.

Journal: The Journal of pharmacology and experimental therapeutics 20110701

Title: Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels.

Journal: Fluids and barriers of the CNS 20110101

Title: CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101001

Title: Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells.

Journal: European journal of immunology 20100901

Title: Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans.

Journal: Environmental health perspectives 20100501

Title: Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium.

Journal: Toxicology 20091221

Title: Inhibition of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090901

Title: Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells.

Journal: The Journal of experimental medicine 20090119

Title: Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor.

Journal: Molecular pharmacology 20060601

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Tags:301326-22-7 Molecular Formula|301326-22-7 MDL|301326-22-7 SMILES|301326-22-7 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
Catalog No.: AA00BE8F
301326-22-7,MFCD00377884
301326-22-7 | 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
Pack Size: 5mg
Purity: 98%
in stock
$77.00 $54.00
Pack Size: 25mg
Purity: ≥95%
in stock
$315.00 $220.00
Pack Size: 50mg
Purity:
in stock
$558.00 $390.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00BE8F
Chemical Name: 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
CAS Number: 301326-22-7
Molecular Formula: C19H19N5O
Molecular Weight: 333.3871
MDL Number: MFCD00377884
SMILES: Cc1cc(ccc1NC(=O)c1ccnn1C)N=Nc1ccccc1C
Properties
Complexity: 482  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.9  
Literature fold

Title: Lymphocyte-Specific Protein Tyrosine Kinase (LCK) is Involved in the Aryl Hydrocarbon Receptor-Mediated Impairment of Immunoglobulin Secretion in Human Primary B Cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20181001

Title: In vitro toxicity and in silico docking analysis of two novel selective AH-receptor modulators.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20181001

Title: Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20180901

Title: Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.

Journal: Toxicology letters20180801

Title: Relative effective potencies of dioxin-like compounds in rodent and human lung cell models.

Journal: Toxicology20180701

Title: Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells.

Journal: Toxicology letters20180601

Title: Suppression of the IgM Response by Aryl Hydrocarbon Receptor Activation in Human Primary B Cells Involves Impairment of Immunoglobulin Secretory Processes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20180501

Title: Diesel exhaust particulate associated chemicals attenuate expression of CXCL10 in human primary bronchial epithelial cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20171201

Title: Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20171201

Title: Actein alleviates 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated cellular dysfunction in osteoblastic MC3T3-E1 cells.

Journal: Environmental toxicology20171201

Title: Editor's Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20171101

Title: Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells.

Journal: Archives of toxicology20170101

Title: SHP-1 is directly activated by the aryl hydrocarbon receptor and regulates BCL-6 in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Journal: Toxicology and applied pharmacology20161101

Title: Activation of aryl hydrocarbon receptor reduces carbendazim-induced cell death.

Journal: Toxicology and applied pharmacology20160901

Title: Aryl hydrocarbon receptor-ligand axis mediates pulmonary fibroblast migration and differentiation through increased arachidonic acid metabolism.

Journal: Toxicology20160831

Title: Benzo[ghi]perylene activates the AHR pathway to exert biological effects on the NL-20 human bronchial cell line.

Journal: Toxicology letters20160810

Title: Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Journal: Toxicology20160810

Title: Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1.

Journal: Toxicology and applied pharmacology20160601

Title: TCDD promoted EMT of hFPECs via AhR, which involved the activation of EGFR/ERK signaling.

Journal: Toxicology and applied pharmacology20160501

Title: Crosstalk between AhR and wnt/β-catenin signal pathways in the cardiac developmental toxicity of PM2.5 in zebrafish embryos.

Journal: Toxicology20160429

Title: Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.

Journal: Chemical research in toxicology20160119

Title: PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20160101

Title: Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells.

Journal: Toxicology and applied pharmacology20160101

Title: Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator.

Journal: The Journal of toxicological sciences20160101

Title: Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.

Journal: Archives of toxicology20151201

Title: Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells.

Journal: The Journal of toxicological sciences20151201

Title: Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes.

Journal: Toxicology20151104

Title: Cytokine responses induced by diesel exhaust particles are suppressed by PAR-2 silencing and antioxidant treatment, and driven by polar and non-polar soluble constituents.

Journal: Toxicology letters20151014

Title: Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20151001

Title: Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.

Journal: Chemical research in toxicology20150817

Title: Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.

Journal: Chemical research in toxicology20150518

Title: Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital.

Journal: Toxicology20150203

Title: PCB126 inhibits adipogenesis of human preadipocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20150201

Title: Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation.

Journal: Toxicology and applied pharmacology20141101

Title: The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway.

Journal: Toxicology and applied pharmacology20141101

Title: The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines.

Journal: Molecular carcinogenesis20141001

Title: Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line.

Journal: International journal of environmental research and public health20140901

Title: Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesion molecule-1 (ICAM-1).

Journal: Toxicological sciences : an official journal of the Society of Toxicology20140701

Title: A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20140401

Title: Differentiation of human placental BeWo cells by the environmental contaminant benzo(a)pyrene.

Journal: Chemico-biological interactions20140305

Title: Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20140301

Title: The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development.

Journal: PloS one20140101

Title: Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells.

Journal: Toxicology letters20131023

Title: Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20130501

Title: AhR-mediated effects of dioxin on neuronal acetylcholinesterase expression in vitro.

Journal: Environmental health perspectives20130501

Title: AhR-mediated changes in global gene expression in rat liver progenitor cells.

Journal: Archives of toxicology20130401

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20130301

Title: Cyprodinil as an activator of aryl hydrocarbon receptor.

Journal: Toxicology20130208

Title: Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis.

Journal: Environmental health perspectives20130101

Title: Cigarette smoke condensate induces aryl hydrocarbon receptor-dependent changes in gene expression in spermatocytes.

Journal: Reproductive toxicology (Elmsford, N.Y.)20121201

Title: The androgenic anabolic steroid tetrahydrogestrinone produces dioxin-like effects via the aryl hydrocarbon receptor.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20121001

Title: Cardiosulfa induces heart deformation in zebrafish through the AhR-mediated, CYP1A-independent pathway.

Journal: Chembiochem : a European journal of chemical biology20120709

Title: FOXA1 is essential for aryl hydrocarbon receptor-dependent regulation of cyclin G2.

Journal: Molecular cancer research : MCR20120501

Title: Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells.

Journal: Biomedical research (Tokyo, Japan)20120401

Title: Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor.

Journal: Molecular pharmacology20120101

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin's suppression of 1-nitropyrene-induced p53 expression is mediated by cytochrome P450 1A1.

Journal: Chemical research in toxicology20111219

Title: The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachloro-dibenzo-p-dioxin (TCDD) alters early embryonic development in a rat IVF exposure model.

Journal: Reproductive toxicology (Elmsford, N.Y.)20111101

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription.

Journal: American journal of respiratory cell and molecular biology20110801

Title: Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells.

Journal: Toxicology20110711

Title: Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism.

Journal: The Journal of pharmacology and experimental therapeutics20110701

Title: Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels.

Journal: Fluids and barriers of the CNS20110101

Title: CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20101001

Title: Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells.

Journal: European journal of immunology20100901

Title: Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans.

Journal: Environmental health perspectives20100501

Title: Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium.

Journal: Toxicology20091221

Title: Inhibition of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20090901

Title: Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells.

Journal: The Journal of experimental medicine20090119

Title: Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor.

Journal: Molecular pharmacology20060601

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